| Full name: glyoxylate and hydroxypyruvate reductase | Alias Symbol: PH2 | ||
| Type: protein-coding gene | Cytoband: 9p13.2 | ||
| Entrez ID: 9380 | HGNC ID: HGNC:4570 | Ensembl Gene: ENSG00000137106 | OMIM ID: 604296 |
Expression of GRHPR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRHPR | 9380 | 214864_s_at | -0.4874 | 0.0545 | |
| GSE20347 | GRHPR | 9380 | 214864_s_at | -0.6013 | 0.0001 | |
| GSE23400 | GRHPR | 9380 | 201347_x_at | -0.1717 | 0.0073 | |
| GSE26886 | GRHPR | 9380 | 214864_s_at | -0.2803 | 0.1505 | |
| GSE29001 | GRHPR | 9380 | 214864_s_at | -0.2953 | 0.3195 | |
| GSE38129 | GRHPR | 9380 | 201347_x_at | -0.4791 | 0.0000 | |
| GSE45670 | GRHPR | 9380 | 214864_s_at | -0.2100 | 0.1302 | |
| GSE63941 | GRHPR | 9380 | 201347_x_at | 0.1471 | 0.7379 | |
| GSE77861 | GRHPR | 9380 | 214864_s_at | -0.5584 | 0.0137 | |
| GSE97050 | GRHPR | 9380 | A_23_P60225 | -0.3856 | 0.1417 | |
| SRP007169 | GRHPR | 9380 | RNAseq | -1.0400 | 0.0045 | |
| SRP008496 | GRHPR | 9380 | RNAseq | -0.6056 | 0.0088 | |
| SRP064894 | GRHPR | 9380 | RNAseq | -0.0584 | 0.7816 | |
| SRP133303 | GRHPR | 9380 | RNAseq | -0.5913 | 0.0010 | |
| SRP159526 | GRHPR | 9380 | RNAseq | -0.8644 | 0.0000 | |
| SRP193095 | GRHPR | 9380 | RNAseq | -0.6415 | 0.0000 | |
| SRP219564 | GRHPR | 9380 | RNAseq | -0.2390 | 0.5471 | |
| TCGA | GRHPR | 9380 | RNAseq | -0.1038 | 0.0729 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GRHPR expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GRHPR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRHPR | 9380 | 3 | 13 | 14 | |
| GSE20123 | GRHPR | 9380 | 3 | 13 | 14 | |
| GSE43470 | GRHPR | 9380 | 1 | 12 | 30 | |
| GSE46452 | GRHPR | 9380 | 6 | 15 | 38 | |
| GSE47630 | GRHPR | 9380 | 1 | 20 | 19 | |
| GSE54993 | GRHPR | 9380 | 6 | 0 | 64 | |
| GSE54994 | GRHPR | 9380 | 5 | 13 | 35 | |
| GSE60625 | GRHPR | 9380 | 0 | 0 | 11 | |
| GSE74703 | GRHPR | 9380 | 1 | 8 | 27 | |
| GSE74704 | GRHPR | 9380 | 0 | 10 | 10 | |
| TCGA | GRHPR | 9380 | 14 | 44 | 38 |
Total number of gains: 40; Total number of losses: 148; Total Number of normals: 300.
Somatic mutations of GRHPR:
Generating mutation plots.
Highly correlated genes for GRHPR:
Showing top 20/749 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRHPR | ENSA | 0.831287 | 3 | 0 | 3 |
| GRHPR | HDHD2 | 0.826441 | 3 | 0 | 3 |
| GRHPR | MSRB3 | 0.816927 | 3 | 0 | 3 |
| GRHPR | PDCD4 | 0.815527 | 3 | 0 | 3 |
| GRHPR | NFIA | 0.813771 | 3 | 0 | 3 |
| GRHPR | SYNE1 | 0.806231 | 3 | 0 | 3 |
| GRHPR | ARRB1 | 0.803262 | 3 | 0 | 3 |
| GRHPR | CCDC154 | 0.796968 | 3 | 0 | 3 |
| GRHPR | ST6GALNAC6 | 0.791838 | 3 | 0 | 3 |
| GRHPR | LDB3 | 0.791558 | 3 | 0 | 3 |
| GRHPR | SPAG8 | 0.779907 | 3 | 0 | 3 |
| GRHPR | TLE2 | 0.779697 | 3 | 0 | 3 |
| GRHPR | MAGEC1 | 0.777704 | 3 | 0 | 3 |
| GRHPR | PLAC9 | 0.775558 | 3 | 0 | 3 |
| GRHPR | DOCK8 | 0.774289 | 3 | 0 | 3 |
| GRHPR | SLTM | 0.771221 | 3 | 0 | 3 |
| GRHPR | PODN | 0.769299 | 3 | 0 | 3 |
| GRHPR | WNT5B | 0.769037 | 4 | 0 | 4 |
| GRHPR | COPZ1 | 0.767661 | 3 | 0 | 3 |
| GRHPR | ALKBH7 | 0.763359 | 3 | 0 | 3 |
For details and further investigation, click here
