| Full name: transmembrane protein 140 | Alias Symbol: FLJ11000 | ||
| Type: protein-coding gene | Cytoband: 7q33 | ||
| Entrez ID: 55281 | HGNC ID: HGNC:21870 | Ensembl Gene: ENSG00000146859 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM140:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM140 | 55281 | 218999_at | 0.0799 | 0.9466 | |
| GSE20347 | TMEM140 | 55281 | 218999_at | 0.3415 | 0.0325 | |
| GSE23400 | TMEM140 | 55281 | 218999_at | 0.0065 | 0.9144 | |
| GSE26886 | TMEM140 | 55281 | 218999_at | 0.4884 | 0.0296 | |
| GSE29001 | TMEM140 | 55281 | 218999_at | 0.5556 | 0.0229 | |
| GSE38129 | TMEM140 | 55281 | 218999_at | 0.0437 | 0.8675 | |
| GSE45670 | TMEM140 | 55281 | 218999_at | -0.0958 | 0.8076 | |
| GSE53622 | TMEM140 | 55281 | 64320 | 0.4186 | 0.0002 | |
| GSE53624 | TMEM140 | 55281 | 64320 | 0.4928 | 0.0000 | |
| GSE63941 | TMEM140 | 55281 | 218999_at | -3.1814 | 0.0000 | |
| GSE77861 | TMEM140 | 55281 | 218999_at | 0.0716 | 0.4994 | |
| GSE97050 | TMEM140 | 55281 | A_24_P372134 | 0.0478 | 0.8736 | |
| SRP007169 | TMEM140 | 55281 | RNAseq | 1.6506 | 0.0004 | |
| SRP008496 | TMEM140 | 55281 | RNAseq | 2.0828 | 0.0000 | |
| SRP064894 | TMEM140 | 55281 | RNAseq | 0.8064 | 0.0003 | |
| SRP133303 | TMEM140 | 55281 | RNAseq | 0.5885 | 0.0000 | |
| SRP159526 | TMEM140 | 55281 | RNAseq | 0.4381 | 0.3373 | |
| SRP193095 | TMEM140 | 55281 | RNAseq | 0.7574 | 0.0000 | |
| SRP219564 | TMEM140 | 55281 | RNAseq | 0.6886 | 0.1228 | |
| TCGA | TMEM140 | 55281 | RNAseq | -0.0063 | 0.9211 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by TMEM140 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM140:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM140 | 55281 | 5 | 2 | 23 | |
| GSE20123 | TMEM140 | 55281 | 5 | 2 | 23 | |
| GSE43470 | TMEM140 | 55281 | 2 | 3 | 38 | |
| GSE46452 | TMEM140 | 55281 | 7 | 2 | 50 | |
| GSE47630 | TMEM140 | 55281 | 7 | 4 | 29 | |
| GSE54993 | TMEM140 | 55281 | 3 | 5 | 62 | |
| GSE54994 | TMEM140 | 55281 | 6 | 8 | 39 | |
| GSE60625 | TMEM140 | 55281 | 0 | 0 | 11 | |
| GSE74703 | TMEM140 | 55281 | 2 | 3 | 31 | |
| GSE74704 | TMEM140 | 55281 | 2 | 2 | 16 | |
| TCGA | TMEM140 | 55281 | 28 | 23 | 45 |
Total number of gains: 67; Total number of losses: 54; Total Number of normals: 367.
Somatic mutations of TMEM140:
Generating mutation plots.
Highly correlated genes for TMEM140:
Showing top 20/975 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM140 | HAVCR2 | 0.795593 | 3 | 0 | 3 |
| TMEM140 | NAP1L1 | 0.792633 | 3 | 0 | 3 |
| TMEM140 | ST6GALNAC6 | 0.766981 | 3 | 0 | 3 |
| TMEM140 | TAB1 | 0.763492 | 3 | 0 | 3 |
| TMEM140 | ZNF382 | 0.760512 | 3 | 0 | 3 |
| TMEM140 | PRPH2 | 0.753056 | 3 | 0 | 3 |
| TMEM140 | PRICKLE2 | 0.751579 | 3 | 0 | 3 |
| TMEM140 | PTGFR | 0.740541 | 3 | 0 | 3 |
| TMEM140 | RASSF4 | 0.737275 | 6 | 0 | 6 |
| TMEM140 | RAB7B | 0.726111 | 3 | 0 | 3 |
| TMEM140 | CXCL5 | 0.725149 | 4 | 0 | 3 |
| TMEM140 | C1QC | 0.724131 | 6 | 0 | 6 |
| TMEM140 | C19orf18 | 0.721174 | 3 | 0 | 3 |
| TMEM140 | ANK2 | 0.718058 | 4 | 0 | 4 |
| TMEM140 | USP9Y | 0.715271 | 3 | 0 | 3 |
| TMEM140 | C19orf38 | 0.714226 | 3 | 0 | 3 |
| TMEM140 | DHRSX | 0.713094 | 3 | 0 | 3 |
| TMEM140 | MSRB3 | 0.709985 | 3 | 0 | 3 |
| TMEM140 | ZNF334 | 0.708352 | 3 | 0 | 3 |
| TMEM140 | AIDA | 0.705415 | 4 | 0 | 3 |
For details and further investigation, click here
