| Full name: syntaxin 16 | Alias Symbol: hsyn16|SYN16 | ||
| Type: protein-coding gene | Cytoband: 20q13.32 | ||
| Entrez ID: 8675 | HGNC ID: HGNC:11431 | Ensembl Gene: ENSG00000124222 | OMIM ID: 603666 |
| Drug and gene relationship at DGIdb | |||
Expression of STX16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STX16 | 8675 | 221500_s_at | 0.4081 | 0.1726 | |
| GSE20347 | STX16 | 8675 | 221500_s_at | 0.2950 | 0.0090 | |
| GSE23400 | STX16 | 8675 | 221500_s_at | 0.5023 | 0.0000 | |
| GSE26886 | STX16 | 8675 | 221500_s_at | 0.1446 | 0.5267 | |
| GSE29001 | STX16 | 8675 | 221500_s_at | 0.5550 | 0.0170 | |
| GSE38129 | STX16 | 8675 | 221500_s_at | 0.2592 | 0.0105 | |
| GSE45670 | STX16 | 8675 | 221500_s_at | 0.1883 | 0.2141 | |
| GSE53622 | STX16 | 8675 | 134628 | 0.3564 | 0.0000 | |
| GSE53624 | STX16 | 8675 | 20135 | 0.2406 | 0.0000 | |
| GSE63941 | STX16 | 8675 | 221500_s_at | -0.0606 | 0.8947 | |
| GSE77861 | STX16 | 8675 | 221500_s_at | 0.7076 | 0.0159 | |
| GSE97050 | STX16 | 8675 | A_33_P3332860 | 0.3024 | 0.5099 | |
| SRP007169 | STX16 | 8675 | RNAseq | 0.3307 | 0.2784 | |
| SRP008496 | STX16 | 8675 | RNAseq | 0.2467 | 0.1436 | |
| SRP064894 | STX16 | 8675 | RNAseq | 0.3972 | 0.0247 | |
| SRP133303 | STX16 | 8675 | RNAseq | 0.2998 | 0.0038 | |
| SRP159526 | STX16 | 8675 | RNAseq | 0.3560 | 0.3724 | |
| SRP193095 | STX16 | 8675 | RNAseq | 0.3960 | 0.0055 | |
| SRP219564 | STX16 | 8675 | RNAseq | 0.1948 | 0.3733 | |
| TCGA | STX16 | 8675 | RNAseq | 0.0472 | 0.2990 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STX16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STX16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STX16 | 8675 | 14 | 2 | 14 | |
| GSE20123 | STX16 | 8675 | 14 | 2 | 14 | |
| GSE43470 | STX16 | 8675 | 13 | 0 | 30 | |
| GSE46452 | STX16 | 8675 | 29 | 0 | 30 | |
| GSE47630 | STX16 | 8675 | 24 | 1 | 15 | |
| GSE54993 | STX16 | 8675 | 0 | 17 | 53 | |
| GSE54994 | STX16 | 8675 | 29 | 0 | 24 | |
| GSE60625 | STX16 | 8675 | 0 | 0 | 11 | |
| GSE74703 | STX16 | 8675 | 11 | 0 | 25 | |
| GSE74704 | STX16 | 8675 | 11 | 0 | 9 | |
| TCGA | STX16 | 8675 | 43 | 4 | 49 |
Total number of gains: 188; Total number of losses: 26; Total Number of normals: 274.
Somatic mutations of STX16:
Generating mutation plots.
Highly correlated genes for STX16:
Showing top 20/929 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STX16 | CPNE8 | 0.853317 | 3 | 0 | 3 |
| STX16 | ALS2 | 0.847334 | 3 | 0 | 3 |
| STX16 | PDP1 | 0.807324 | 3 | 0 | 3 |
| STX16 | NUDCD1 | 0.796269 | 3 | 0 | 3 |
| STX16 | SLC7A6OS | 0.790542 | 3 | 0 | 3 |
| STX16 | SLC41A1 | 0.787635 | 3 | 0 | 3 |
| STX16 | SLC25A32 | 0.782394 | 4 | 0 | 4 |
| STX16 | BCORL1 | 0.77589 | 3 | 0 | 3 |
| STX16 | CMTM4 | 0.775291 | 3 | 0 | 3 |
| STX16 | UXS1 | 0.771209 | 3 | 0 | 3 |
| STX16 | RIOK1 | 0.765571 | 3 | 0 | 3 |
| STX16 | SMARCA5 | 0.765157 | 3 | 0 | 3 |
| STX16 | NUF2 | 0.764835 | 3 | 0 | 3 |
| STX16 | PDCD2L | 0.762698 | 3 | 0 | 3 |
| STX16 | LYAR | 0.756611 | 4 | 0 | 3 |
| STX16 | FAM86C1 | 0.750841 | 3 | 0 | 3 |
| STX16 | USP21 | 0.742944 | 3 | 0 | 3 |
| STX16 | ZNF791 | 0.741662 | 3 | 0 | 3 |
| STX16 | MZT1 | 0.739736 | 3 | 0 | 3 |
| STX16 | CCDC127 | 0.733404 | 3 | 0 | 3 |
For details and further investigation, click here
