| Full name: programmed cell death 2 like | Alias Symbol: MGC13096 | ||
| Type: protein-coding gene | Cytoband: 19q13.11 | ||
| Entrez ID: 84306 | HGNC ID: HGNC:28194 | Ensembl Gene: ENSG00000126249 | OMIM ID: 615661 |
| Drug and gene relationship at DGIdb | |||
Expression of PDCD2L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDCD2L | 84306 | 224467_s_at | 1.0780 | 0.0137 | |
| GSE26886 | PDCD2L | 84306 | 224467_s_at | 0.6544 | 0.0296 | |
| GSE45670 | PDCD2L | 84306 | 224467_s_at | 0.7623 | 0.0047 | |
| GSE53622 | PDCD2L | 84306 | 111387 | 0.6526 | 0.0000 | |
| GSE53624 | PDCD2L | 84306 | 111387 | 0.9714 | 0.0000 | |
| GSE63941 | PDCD2L | 84306 | 224467_s_at | 0.9024 | 0.2962 | |
| GSE77861 | PDCD2L | 84306 | 224467_s_at | 0.6928 | 0.0341 | |
| GSE97050 | PDCD2L | 84306 | A_23_P27947 | 0.3943 | 0.2423 | |
| SRP007169 | PDCD2L | 84306 | RNAseq | 1.0773 | 0.0428 | |
| SRP008496 | PDCD2L | 84306 | RNAseq | 1.2074 | 0.0071 | |
| SRP064894 | PDCD2L | 84306 | RNAseq | 1.0616 | 0.0005 | |
| SRP133303 | PDCD2L | 84306 | RNAseq | 1.0638 | 0.0036 | |
| SRP159526 | PDCD2L | 84306 | RNAseq | 1.1675 | 0.0012 | |
| SRP193095 | PDCD2L | 84306 | RNAseq | 0.5409 | 0.0002 | |
| SRP219564 | PDCD2L | 84306 | RNAseq | 0.9913 | 0.0747 | |
| TCGA | PDCD2L | 84306 | RNAseq | 0.3015 | 0.0015 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by PDCD2L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDCD2L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDCD2L | 84306 | 6 | 5 | 19 | |
| GSE20123 | PDCD2L | 84306 | 6 | 4 | 20 | |
| GSE43470 | PDCD2L | 84306 | 5 | 7 | 31 | |
| GSE46452 | PDCD2L | 84306 | 48 | 1 | 10 | |
| GSE47630 | PDCD2L | 84306 | 9 | 5 | 26 | |
| GSE54993 | PDCD2L | 84306 | 17 | 3 | 50 | |
| GSE54994 | PDCD2L | 84306 | 9 | 9 | 35 | |
| GSE60625 | PDCD2L | 84306 | 9 | 0 | 2 | |
| GSE74703 | PDCD2L | 84306 | 5 | 4 | 27 | |
| GSE74704 | PDCD2L | 84306 | 6 | 2 | 12 | |
| TCGA | PDCD2L | 84306 | 18 | 12 | 66 |
Total number of gains: 138; Total number of losses: 52; Total Number of normals: 298.
Somatic mutations of PDCD2L:
Generating mutation plots.
Highly correlated genes for PDCD2L:
Showing top 20/1623 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDCD2L | NUP43 | 0.832046 | 3 | 0 | 3 |
| PDCD2L | BRD9 | 0.795819 | 3 | 0 | 3 |
| PDCD2L | ZNF496 | 0.794708 | 4 | 0 | 4 |
| PDCD2L | CPSF7 | 0.792973 | 3 | 0 | 3 |
| PDCD2L | SETDB1 | 0.791853 | 4 | 0 | 4 |
| PDCD2L | RNF4 | 0.774172 | 3 | 0 | 3 |
| PDCD2L | TMTC4 | 0.773844 | 4 | 0 | 3 |
| PDCD2L | OPLAH | 0.773643 | 3 | 0 | 3 |
| PDCD2L | SS18L1 | 0.772726 | 3 | 0 | 3 |
| PDCD2L | FAM86C1 | 0.772723 | 3 | 0 | 3 |
| PDCD2L | TRIO | 0.767119 | 3 | 0 | 3 |
| PDCD2L | CDCA2 | 0.764956 | 4 | 0 | 4 |
| PDCD2L | PTDSS1 | 0.762726 | 7 | 0 | 7 |
| PDCD2L | STX16 | 0.762698 | 3 | 0 | 3 |
| PDCD2L | ZNF584 | 0.756855 | 3 | 0 | 3 |
| PDCD2L | C1orf115 | 0.755167 | 3 | 0 | 3 |
| PDCD2L | DGKH | 0.755042 | 3 | 0 | 3 |
| PDCD2L | PACS1 | 0.754823 | 3 | 0 | 3 |
| PDCD2L | DONSON | 0.753246 | 5 | 0 | 5 |
| PDCD2L | ZNRF3 | 0.752564 | 3 | 0 | 3 |
For details and further investigation, click here
