| Full name: syntaxin 1B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 112755 | HGNC ID: HGNC:18539 | Ensembl Gene: ENSG00000099365 | OMIM ID: 601485 |
| Drug and gene relationship at DGIdb | |||
Expression of STX1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STX1B | 112755 | 230691_at | -0.2014 | 0.4549 | |
| GSE26886 | STX1B | 112755 | 230691_at | -0.1315 | 0.1600 | |
| GSE45670 | STX1B | 112755 | 230691_at | 0.0615 | 0.5361 | |
| GSE53622 | STX1B | 112755 | 54984 | 0.2223 | 0.0000 | |
| GSE53624 | STX1B | 112755 | 54984 | 0.2292 | 0.2072 | |
| GSE63941 | STX1B | 112755 | 230691_at | -0.0068 | 0.9774 | |
| GSE77861 | STX1B | 112755 | 230691_at | -0.0907 | 0.6521 | |
| GSE97050 | STX1B | 112755 | A_23_P152462 | 0.2030 | 0.3384 | |
| SRP064894 | STX1B | 112755 | RNAseq | -0.4255 | 0.1680 | |
| SRP133303 | STX1B | 112755 | RNAseq | -0.6723 | 0.0035 | |
| SRP159526 | STX1B | 112755 | RNAseq | -0.8218 | 0.1348 | |
| SRP193095 | STX1B | 112755 | RNAseq | -0.8300 | 0.0000 | |
| SRP219564 | STX1B | 112755 | RNAseq | -0.8402 | 0.0626 | |
| TCGA | STX1B | 112755 | RNAseq | -0.0232 | 0.9200 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STX1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STX1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STX1B | 112755 | 5 | 5 | 20 | |
| GSE20123 | STX1B | 112755 | 5 | 4 | 21 | |
| GSE43470 | STX1B | 112755 | 3 | 3 | 37 | |
| GSE46452 | STX1B | 112755 | 38 | 1 | 20 | |
| GSE47630 | STX1B | 112755 | 11 | 7 | 22 | |
| GSE54993 | STX1B | 112755 | 2 | 5 | 63 | |
| GSE54994 | STX1B | 112755 | 5 | 9 | 39 | |
| GSE60625 | STX1B | 112755 | 4 | 0 | 7 | |
| GSE74703 | STX1B | 112755 | 3 | 2 | 31 | |
| GSE74704 | STX1B | 112755 | 3 | 2 | 15 | |
| TCGA | STX1B | 112755 | 20 | 10 | 66 |
Total number of gains: 99; Total number of losses: 48; Total Number of normals: 341.
Somatic mutations of STX1B:
Generating mutation plots.
Highly correlated genes for STX1B:
Showing top 20/222 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STX1B | ACBD4 | 0.817 | 3 | 0 | 3 |
| STX1B | SLC6A13 | 0.804174 | 3 | 0 | 3 |
| STX1B | ATP2B2 | 0.766347 | 3 | 0 | 3 |
| STX1B | C10orf90 | 0.76536 | 3 | 0 | 3 |
| STX1B | SLC16A11 | 0.762896 | 3 | 0 | 3 |
| STX1B | KIFC2 | 0.759092 | 4 | 0 | 4 |
| STX1B | PAX2 | 0.757292 | 3 | 0 | 3 |
| STX1B | ASRGL1 | 0.751733 | 3 | 0 | 3 |
| STX1B | TSPAN11 | 0.751416 | 4 | 0 | 4 |
| STX1B | ARHGDIG | 0.746174 | 3 | 0 | 3 |
| STX1B | GNB3 | 0.740681 | 4 | 0 | 4 |
| STX1B | SNED1 | 0.734966 | 4 | 0 | 4 |
| STX1B | MUC2 | 0.732179 | 4 | 0 | 3 |
| STX1B | SHISA8 | 0.725351 | 3 | 0 | 3 |
| STX1B | KRTAP3-1 | 0.723341 | 3 | 0 | 3 |
| STX1B | ADM2 | 0.722469 | 4 | 0 | 3 |
| STX1B | LGALS12 | 0.721868 | 3 | 0 | 3 |
| STX1B | RXFP3 | 0.720538 | 3 | 0 | 3 |
| STX1B | ZFPM1 | 0.720171 | 3 | 0 | 3 |
| STX1B | C10orf91 | 0.714404 | 3 | 0 | 3 |
For details and further investigation, click here
