| Full name: Dexi homolog | Alias Symbol: MYLE | ||
| Type: protein-coding gene | Cytoband: 16p13.13 | ||
| Entrez ID: 28955 | HGNC ID: HGNC:13267 | Ensembl Gene: ENSG00000182108 | OMIM ID: 617901 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DEXI:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DEXI | 28955 | 203733_at | 0.1433 | 0.8348 | |
| GSE20347 | DEXI | 28955 | 203733_at | 0.1438 | 0.2474 | |
| GSE23400 | DEXI | 28955 | 203733_at | 0.1424 | 0.0400 | |
| GSE26886 | DEXI | 28955 | 203733_at | 0.5834 | 0.0019 | |
| GSE29001 | DEXI | 28955 | 203733_at | 0.6321 | 0.0011 | |
| GSE38129 | DEXI | 28955 | 203733_at | 0.0480 | 0.8332 | |
| GSE45670 | DEXI | 28955 | 203733_at | -0.0920 | 0.5804 | |
| GSE63941 | DEXI | 28955 | 203733_at | -1.1314 | 0.0036 | |
| GSE77861 | DEXI | 28955 | 203733_at | 0.0934 | 0.6004 | |
| GSE97050 | DEXI | 28955 | A_24_P144377 | -0.1298 | 0.5207 | |
| SRP007169 | DEXI | 28955 | RNAseq | -0.0603 | 0.8761 | |
| SRP008496 | DEXI | 28955 | RNAseq | 0.3227 | 0.2011 | |
| SRP064894 | DEXI | 28955 | RNAseq | 0.3524 | 0.2566 | |
| SRP133303 | DEXI | 28955 | RNAseq | 0.3280 | 0.0413 | |
| SRP159526 | DEXI | 28955 | RNAseq | -0.1026 | 0.5930 | |
| SRP193095 | DEXI | 28955 | RNAseq | 0.3192 | 0.0091 | |
| SRP219564 | DEXI | 28955 | RNAseq | 0.0925 | 0.8501 | |
| TCGA | DEXI | 28955 | RNAseq | -0.1515 | 0.0047 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DEXI expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of DEXI:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DEXI | 28955 | 5 | 4 | 21 | |
| GSE20123 | DEXI | 28955 | 5 | 3 | 22 | |
| GSE43470 | DEXI | 28955 | 3 | 3 | 37 | |
| GSE46452 | DEXI | 28955 | 38 | 1 | 20 | |
| GSE47630 | DEXI | 28955 | 14 | 6 | 20 | |
| GSE54993 | DEXI | 28955 | 3 | 5 | 62 | |
| GSE54994 | DEXI | 28955 | 5 | 9 | 39 | |
| GSE60625 | DEXI | 28955 | 4 | 0 | 7 | |
| GSE74703 | DEXI | 28955 | 3 | 2 | 31 | |
| GSE74704 | DEXI | 28955 | 2 | 1 | 17 | |
| TCGA | DEXI | 28955 | 20 | 12 | 64 |
Total number of gains: 102; Total number of losses: 46; Total Number of normals: 340.
Somatic mutations of DEXI:
Generating mutation plots.
Highly correlated genes for DEXI:
Showing top 20/912 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DEXI | VSTM4 | 0.810484 | 3 | 0 | 3 |
| DEXI | RBM33 | 0.80641 | 3 | 0 | 3 |
| DEXI | MS4A4A | 0.795299 | 3 | 0 | 3 |
| DEXI | BBS9 | 0.79482 | 3 | 0 | 3 |
| DEXI | PLXNA1 | 0.784138 | 3 | 0 | 3 |
| DEXI | KCTD2 | 0.784062 | 3 | 0 | 3 |
| DEXI | CDC14B | 0.783792 | 3 | 0 | 3 |
| DEXI | SLC25A36 | 0.775532 | 3 | 0 | 3 |
| DEXI | CHCHD6 | 0.771819 | 3 | 0 | 3 |
| DEXI | TATDN2 | 0.771457 | 3 | 0 | 3 |
| DEXI | DTYMK | 0.770129 | 3 | 0 | 3 |
| DEXI | NTPCR | 0.769696 | 3 | 0 | 3 |
| DEXI | PRMT6 | 0.762138 | 3 | 0 | 3 |
| DEXI | SVEP1 | 0.762123 | 3 | 0 | 3 |
| DEXI | GPKOW | 0.753047 | 3 | 0 | 3 |
| DEXI | FAU | 0.750438 | 3 | 0 | 3 |
| DEXI | PRADC1 | 0.742368 | 3 | 0 | 3 |
| DEXI | FGL2 | 0.741783 | 3 | 0 | 3 |
| DEXI | YLPM1 | 0.733594 | 5 | 0 | 5 |
| DEXI | ATL1 | 0.733591 | 3 | 0 | 3 |
For details and further investigation, click here
