| Full name: synaptonemal complex central element protein 1 | Alias Symbol: bA108K14.6|CT76 | ||
| Type: protein-coding gene | Cytoband: 10q26.3 | ||
| Entrez ID: 93426 | HGNC ID: HGNC:28852 | Ensembl Gene: ENSG00000171772 | OMIM ID: 611486 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SYCE1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYCE1 | 93426 | 1554675_a_at | -0.0358 | 0.8897 | |
| GSE26886 | SYCE1 | 93426 | 1554675_a_at | 0.3710 | 0.0420 | |
| GSE45670 | SYCE1 | 93426 | 1554675_a_at | 0.0546 | 0.5886 | |
| GSE53622 | SYCE1 | 93426 | 5315 | -0.0719 | 0.3689 | |
| GSE53624 | SYCE1 | 93426 | 5315 | -0.4621 | 0.0000 | |
| GSE63941 | SYCE1 | 93426 | 1554675_a_at | 0.1203 | 0.4026 | |
| GSE77861 | SYCE1 | 93426 | 1554675_a_at | -0.0750 | 0.4351 | |
| TCGA | SYCE1 | 93426 | RNAseq | -1.5835 | 0.1101 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SYCE1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYCE1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYCE1 | 93426 | 4 | 5 | 21 | |
| GSE20123 | SYCE1 | 93426 | 4 | 6 | 20 | |
| GSE43470 | SYCE1 | 93426 | 0 | 9 | 34 | |
| GSE46452 | SYCE1 | 93426 | 1 | 11 | 47 | |
| GSE47630 | SYCE1 | 93426 | 4 | 13 | 23 | |
| GSE54993 | SYCE1 | 93426 | 8 | 2 | 60 | |
| GSE54994 | SYCE1 | 93426 | 1 | 9 | 43 | |
| GSE60625 | SYCE1 | 93426 | 0 | 0 | 11 | |
| GSE74703 | SYCE1 | 93426 | 0 | 7 | 29 | |
| GSE74704 | SYCE1 | 93426 | 3 | 3 | 14 | |
| TCGA | SYCE1 | 93426 | 7 | 28 | 61 |
Total number of gains: 32; Total number of losses: 93; Total Number of normals: 363.
Somatic mutations of SYCE1:
Generating mutation plots.
Highly correlated genes for SYCE1:
Showing top 20/204 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYCE1 | MOG | 0.766721 | 3 | 0 | 3 |
| SYCE1 | ACRBP | 0.75505 | 3 | 0 | 3 |
| SYCE1 | GRIK4 | 0.720605 | 3 | 0 | 3 |
| SYCE1 | C2orf73 | 0.715647 | 3 | 0 | 3 |
| SYCE1 | FAM120C | 0.687243 | 3 | 0 | 3 |
| SYCE1 | JAZF1-AS1 | 0.685885 | 3 | 0 | 3 |
| SYCE1 | RFPL1S | 0.685789 | 3 | 0 | 3 |
| SYCE1 | TCTA | 0.684478 | 3 | 0 | 3 |
| SYCE1 | PTH2 | 0.682717 | 4 | 0 | 4 |
| SYCE1 | KCNJ9 | 0.682397 | 3 | 0 | 3 |
| SYCE1 | LINC00620 | 0.676972 | 3 | 0 | 3 |
| SYCE1 | ZNF169 | 0.674212 | 3 | 0 | 3 |
| SYCE1 | SAMD4A | 0.668621 | 3 | 0 | 3 |
| SYCE1 | LINC00163 | 0.667455 | 4 | 0 | 3 |
| SYCE1 | KCNH3 | 0.666949 | 4 | 0 | 3 |
| SYCE1 | GPHB5 | 0.66664 | 3 | 0 | 3 |
| SYCE1 | DNAAF1 | 0.665693 | 3 | 0 | 3 |
| SYCE1 | RSPH9 | 0.659338 | 4 | 0 | 3 |
| SYCE1 | KRTAP3-1 | 0.652308 | 4 | 0 | 4 |
| SYCE1 | F2RL3 | 0.652288 | 3 | 0 | 3 |
For details and further investigation, click here
