| Full name: parathyroid hormone 2 | Alias Symbol: TIP39 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 113091 | HGNC ID: HGNC:30828 | Ensembl Gene: ENSG00000142538 | OMIM ID: 608386 |
| Drug and gene relationship at DGIdb | |||
Expression of PTH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTH2 | 113091 | 1555238_at | -0.0442 | 0.9065 | |
| GSE26886 | PTH2 | 113091 | 1555238_at | -0.0365 | 0.8341 | |
| GSE45670 | PTH2 | 113091 | 1555238_at | 0.0803 | 0.2863 | |
| GSE53622 | PTH2 | 113091 | 103499 | -0.1927 | 0.0221 | |
| GSE53624 | PTH2 | 113091 | 103499 | -0.5192 | 0.0000 | |
| GSE63941 | PTH2 | 113091 | 1555238_at | 0.3142 | 0.0455 | |
| GSE77861 | PTH2 | 113091 | 1555238_at | -0.0125 | 0.9126 | |
| GSE97050 | PTH2 | 113091 | A_23_P357374 | 0.3681 | 0.3399 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PTH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTH2 | 113091 | 4 | 4 | 22 | |
| GSE20123 | PTH2 | 113091 | 4 | 3 | 23 | |
| GSE43470 | PTH2 | 113091 | 4 | 11 | 28 | |
| GSE46452 | PTH2 | 113091 | 45 | 1 | 13 | |
| GSE47630 | PTH2 | 113091 | 10 | 6 | 24 | |
| GSE54993 | PTH2 | 113091 | 17 | 4 | 49 | |
| GSE54994 | PTH2 | 113091 | 4 | 14 | 35 | |
| GSE60625 | PTH2 | 113091 | 9 | 0 | 2 | |
| GSE74703 | PTH2 | 113091 | 4 | 7 | 25 | |
| GSE74704 | PTH2 | 113091 | 4 | 1 | 15 | |
| TCGA | PTH2 | 113091 | 14 | 19 | 63 |
Total number of gains: 119; Total number of losses: 70; Total Number of normals: 299.
Somatic mutations of PTH2:
Generating mutation plots.
Highly correlated genes for PTH2:
Showing top 20/170 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTH2 | OR10H3 | 0.69366 | 3 | 0 | 3 |
| PTH2 | BANF2 | 0.68553 | 3 | 0 | 3 |
| PTH2 | SYCE1 | 0.682717 | 4 | 0 | 4 |
| PTH2 | ACRBP | 0.652309 | 3 | 0 | 3 |
| PTH2 | ERICH4 | 0.647042 | 3 | 0 | 3 |
| PTH2 | LINC00689 | 0.643488 | 4 | 0 | 3 |
| PTH2 | ANKRD63 | 0.640145 | 3 | 0 | 3 |
| PTH2 | PRR29 | 0.6358 | 4 | 0 | 4 |
| PTH2 | OSM | 0.634363 | 4 | 0 | 3 |
| PTH2 | TPBGL | 0.63358 | 6 | 0 | 5 |
| PTH2 | TBXA2R | 0.633434 | 3 | 0 | 3 |
| PTH2 | GPSM1 | 0.627947 | 3 | 0 | 3 |
| PTH2 | DNAH1 | 0.627036 | 3 | 0 | 3 |
| PTH2 | PLK5 | 0.626356 | 3 | 0 | 3 |
| PTH2 | C8B | 0.62375 | 3 | 0 | 3 |
| PTH2 | LIMD1-AS1 | 0.621869 | 3 | 0 | 3 |
| PTH2 | CDH22 | 0.620397 | 4 | 0 | 3 |
| PTH2 | BPIFA3 | 0.605968 | 3 | 0 | 3 |
| PTH2 | LINC01343 | 0.598966 | 5 | 0 | 4 |
| PTH2 | CA14 | 0.598942 | 4 | 0 | 3 |
For details and further investigation, click here
