| Full name: synaptonemal complex protein 1 | Alias Symbol: HOM-TES-14|SCP1|CT8 | ||
| Type: protein-coding gene | Cytoband: 1p13.2 | ||
| Entrez ID: 6847 | HGNC ID: HGNC:11487 | Ensembl Gene: ENSG00000198765 | OMIM ID: 602162 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SYCP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYCP1 | 6847 | 206740_x_at | 0.0712 | 0.7770 | |
| GSE20347 | SYCP1 | 6847 | 206740_x_at | 0.1028 | 0.1794 | |
| GSE23400 | SYCP1 | 6847 | 206740_x_at | 0.0275 | 0.2984 | |
| GSE26886 | SYCP1 | 6847 | 206740_x_at | 0.0927 | 0.3352 | |
| GSE29001 | SYCP1 | 6847 | 206740_x_at | 0.1556 | 0.5018 | |
| GSE38129 | SYCP1 | 6847 | 206740_x_at | 0.0102 | 0.9181 | |
| GSE45670 | SYCP1 | 6847 | 216917_s_at | -0.0297 | 0.7368 | |
| GSE53622 | SYCP1 | 6847 | 60407 | 0.1336 | 0.0360 | |
| GSE53624 | SYCP1 | 6847 | 60407 | 0.4417 | 0.0000 | |
| GSE63941 | SYCP1 | 6847 | 206740_x_at | -0.0804 | 0.6815 | |
| GSE77861 | SYCP1 | 6847 | 206740_x_at | 0.0340 | 0.6988 | |
| GSE97050 | SYCP1 | 6847 | A_23_P722 | 0.0068 | 0.9801 | |
| TCGA | SYCP1 | 6847 | RNAseq | 0.9237 | 0.5965 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SYCP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYCP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYCP1 | 6847 | 0 | 9 | 21 | |
| GSE20123 | SYCP1 | 6847 | 0 | 9 | 21 | |
| GSE43470 | SYCP1 | 6847 | 0 | 8 | 35 | |
| GSE46452 | SYCP1 | 6847 | 2 | 1 | 56 | |
| GSE47630 | SYCP1 | 6847 | 9 | 5 | 26 | |
| GSE54993 | SYCP1 | 6847 | 0 | 1 | 69 | |
| GSE54994 | SYCP1 | 6847 | 7 | 3 | 43 | |
| GSE60625 | SYCP1 | 6847 | 0 | 0 | 11 | |
| GSE74703 | SYCP1 | 6847 | 0 | 7 | 29 | |
| GSE74704 | SYCP1 | 6847 | 0 | 5 | 15 | |
| TCGA | SYCP1 | 6847 | 12 | 29 | 55 |
Total number of gains: 30; Total number of losses: 77; Total Number of normals: 381.
Somatic mutations of SYCP1:
Generating mutation plots.
Highly correlated genes for SYCP1:
Showing top 20/175 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYCP1 | C16orf95 | 0.727495 | 3 | 0 | 3 |
| SYCP1 | SLC2A8 | 0.701323 | 3 | 0 | 3 |
| SYCP1 | PNMA6A | 0.69209 | 3 | 0 | 3 |
| SYCP1 | TRIM17 | 0.682184 | 3 | 0 | 3 |
| SYCP1 | OR2A5 | 0.675426 | 3 | 0 | 3 |
| SYCP1 | RNF215 | 0.654542 | 3 | 0 | 3 |
| SYCP1 | MPP3 | 0.652627 | 3 | 0 | 3 |
| SYCP1 | HECW1 | 0.650161 | 6 | 0 | 5 |
| SYCP1 | GPR88 | 0.643447 | 4 | 0 | 3 |
| SYCP1 | INSC | 0.640918 | 4 | 0 | 3 |
| SYCP1 | FOXN3-AS2 | 0.637542 | 4 | 0 | 4 |
| SYCP1 | FABP7 | 0.637355 | 3 | 0 | 3 |
| SYCP1 | FFAR1 | 0.633709 | 4 | 0 | 3 |
| SYCP1 | IFNA10 | 0.631079 | 3 | 0 | 3 |
| SYCP1 | LY6G5C | 0.626115 | 4 | 0 | 3 |
| SYCP1 | S100A5 | 0.619524 | 5 | 0 | 3 |
| SYCP1 | ISLR2 | 0.619239 | 5 | 0 | 3 |
| SYCP1 | MAG | 0.617617 | 4 | 0 | 3 |
| SYCP1 | ASPHD1 | 0.611878 | 4 | 0 | 3 |
| SYCP1 | PRODH2 | 0.611647 | 7 | 0 | 3 |
For details and further investigation, click here
