| Full name: membrane palmitoylated protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 4356 | HGNC ID: HGNC:7221 | Ensembl Gene: ENSG00000161647 | OMIM ID: 601114 |
| Drug and gene relationship at DGIdb | |||
Expression of MPP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPP3 | 4356 | 206186_at | 0.1558 | 0.5283 | |
| GSE20347 | MPP3 | 4356 | 206186_at | 0.3249 | 0.0020 | |
| GSE23400 | MPP3 | 4356 | 206186_at | -0.0564 | 0.3753 | |
| GSE26886 | MPP3 | 4356 | 206186_at | 0.4432 | 0.0838 | |
| GSE29001 | MPP3 | 4356 | 206186_at | 0.2003 | 0.4868 | |
| GSE38129 | MPP3 | 4356 | 206186_at | 0.4489 | 0.0003 | |
| GSE45670 | MPP3 | 4356 | 206186_at | 0.1745 | 0.4858 | |
| GSE53622 | MPP3 | 4356 | 943 | 0.2590 | 0.1586 | |
| GSE53624 | MPP3 | 4356 | 943 | 0.6057 | 0.0000 | |
| GSE63941 | MPP3 | 4356 | 206186_at | -0.1164 | 0.7225 | |
| GSE77861 | MPP3 | 4356 | 206186_at | 0.1587 | 0.1340 | |
| GSE97050 | MPP3 | 4356 | A_23_P141345 | 0.1621 | 0.4522 | |
| SRP007169 | MPP3 | 4356 | RNAseq | 1.8721 | 0.0033 | |
| SRP064894 | MPP3 | 4356 | RNAseq | 0.2709 | 0.0962 | |
| SRP133303 | MPP3 | 4356 | RNAseq | 0.6554 | 0.0296 | |
| SRP159526 | MPP3 | 4356 | RNAseq | 0.8135 | 0.0999 | |
| SRP193095 | MPP3 | 4356 | RNAseq | 0.6752 | 0.0004 | |
| SRP219564 | MPP3 | 4356 | RNAseq | 0.1332 | 0.7438 | |
| TCGA | MPP3 | 4356 | RNAseq | 0.2735 | 0.0331 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MPP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPP3 | 4356 | 5 | 2 | 23 | |
| GSE20123 | MPP3 | 4356 | 5 | 2 | 23 | |
| GSE43470 | MPP3 | 4356 | 1 | 2 | 40 | |
| GSE46452 | MPP3 | 4356 | 32 | 0 | 27 | |
| GSE47630 | MPP3 | 4356 | 8 | 1 | 31 | |
| GSE54993 | MPP3 | 4356 | 3 | 4 | 63 | |
| GSE54994 | MPP3 | 4356 | 8 | 6 | 39 | |
| GSE60625 | MPP3 | 4356 | 4 | 0 | 7 | |
| GSE74703 | MPP3 | 4356 | 1 | 1 | 34 | |
| GSE74704 | MPP3 | 4356 | 3 | 1 | 16 | |
| TCGA | MPP3 | 4356 | 23 | 7 | 66 |
Total number of gains: 93; Total number of losses: 26; Total Number of normals: 369.
Somatic mutations of MPP3:
Generating mutation plots.
Highly correlated genes for MPP3:
Showing top 20/154 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPP3 | ORM1 | 0.820282 | 3 | 0 | 3 |
| MPP3 | TBX21 | 0.758282 | 3 | 0 | 3 |
| MPP3 | IL15RA | 0.750307 | 3 | 0 | 3 |
| MPP3 | SLC27A1 | 0.720578 | 3 | 0 | 3 |
| MPP3 | PGPEP1 | 0.716208 | 3 | 0 | 3 |
| MPP3 | GYPE | 0.709519 | 3 | 0 | 3 |
| MPP3 | DLX6-AS1 | 0.703928 | 4 | 0 | 4 |
| MPP3 | VWDE | 0.702178 | 4 | 0 | 3 |
| MPP3 | FASLG | 0.701388 | 3 | 0 | 3 |
| MPP3 | AICDA | 0.688291 | 3 | 0 | 3 |
| MPP3 | HTRA4 | 0.682979 | 4 | 0 | 4 |
| MPP3 | AGAP2 | 0.682352 | 4 | 0 | 3 |
| MPP3 | U2AF1L4 | 0.680802 | 3 | 0 | 3 |
| MPP3 | KIR3DL3 | 0.678432 | 4 | 0 | 3 |
| MPP3 | LYPD6 | 0.677269 | 4 | 0 | 3 |
| MPP3 | PRAME | 0.66455 | 4 | 0 | 4 |
| MPP3 | ZNF236 | 0.664068 | 5 | 0 | 5 |
| MPP3 | MEPE | 0.663841 | 4 | 0 | 3 |
| MPP3 | JAKMIP3 | 0.659807 | 5 | 0 | 4 |
| MPP3 | SYCP1 | 0.652627 | 3 | 0 | 3 |
For details and further investigation, click here
