| Full name: synaptonemal complex protein 2 | Alias Symbol: SCP2 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 10388 | HGNC ID: HGNC:11490 | Ensembl Gene: ENSG00000196074 | OMIM ID: 604105 |
| Drug and gene relationship at DGIdb | |||
Expression of SYCP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYCP2 | 10388 | 206546_at | 1.1474 | 0.1963 | |
| GSE20347 | SYCP2 | 10388 | 206546_at | 0.4940 | 0.0074 | |
| GSE23400 | SYCP2 | 10388 | 206546_at | 0.0919 | 0.0005 | |
| GSE26886 | SYCP2 | 10388 | 206546_at | 0.2038 | 0.0368 | |
| GSE29001 | SYCP2 | 10388 | 206546_at | 0.9346 | 0.0637 | |
| GSE38129 | SYCP2 | 10388 | 206546_at | 0.7149 | 0.0002 | |
| GSE45670 | SYCP2 | 10388 | 206546_at | 0.6881 | 0.1348 | |
| GSE53622 | SYCP2 | 10388 | 30362 | 0.9899 | 0.0007 | |
| GSE53624 | SYCP2 | 10388 | 30362 | 0.9942 | 0.0000 | |
| GSE63941 | SYCP2 | 10388 | 206546_at | 0.7605 | 0.5236 | |
| GSE77861 | SYCP2 | 10388 | 206546_at | 0.2146 | 0.1692 | |
| GSE97050 | SYCP2 | 10388 | A_23_P210675 | 0.2988 | 0.2729 | |
| SRP007169 | SYCP2 | 10388 | RNAseq | 1.3641 | 0.1165 | |
| SRP064894 | SYCP2 | 10388 | RNAseq | 1.4575 | 0.0007 | |
| SRP133303 | SYCP2 | 10388 | RNAseq | 2.0641 | 0.0000 | |
| SRP159526 | SYCP2 | 10388 | RNAseq | 2.4817 | 0.0071 | |
| SRP193095 | SYCP2 | 10388 | RNAseq | 0.8419 | 0.0091 | |
| SRP219564 | SYCP2 | 10388 | RNAseq | 1.8911 | 0.0022 | |
| TCGA | SYCP2 | 10388 | RNAseq | -0.2807 | 0.3340 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by SYCP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYCP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYCP2 | 10388 | 13 | 2 | 15 | |
| GSE20123 | SYCP2 | 10388 | 13 | 2 | 15 | |
| GSE43470 | SYCP2 | 10388 | 13 | 0 | 30 | |
| GSE46452 | SYCP2 | 10388 | 29 | 0 | 30 | |
| GSE47630 | SYCP2 | 10388 | 24 | 1 | 15 | |
| GSE54993 | SYCP2 | 10388 | 0 | 17 | 53 | |
| GSE54994 | SYCP2 | 10388 | 29 | 0 | 24 | |
| GSE60625 | SYCP2 | 10388 | 0 | 0 | 11 | |
| GSE74703 | SYCP2 | 10388 | 11 | 0 | 25 | |
| GSE74704 | SYCP2 | 10388 | 10 | 0 | 10 | |
| TCGA | SYCP2 | 10388 | 43 | 4 | 49 |
Total number of gains: 185; Total number of losses: 26; Total Number of normals: 277.
Somatic mutations of SYCP2:
Generating mutation plots.
Highly correlated genes for SYCP2:
Showing top 20/504 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYCP2 | SEC61A2 | 0.75327 | 3 | 0 | 3 |
| SYCP2 | CHST1 | 0.750403 | 3 | 0 | 3 |
| SYCP2 | TAF4B | 0.736524 | 3 | 0 | 3 |
| SYCP2 | ZFYVE26 | 0.725312 | 3 | 0 | 3 |
| SYCP2 | CCDC127 | 0.710192 | 3 | 0 | 3 |
| SYCP2 | TGFBRAP1 | 0.706869 | 3 | 0 | 3 |
| SYCP2 | LYAR | 0.701624 | 3 | 0 | 3 |
| SYCP2 | GRAMD4 | 0.701217 | 3 | 0 | 3 |
| SYCP2 | HOXD8 | 0.699812 | 3 | 0 | 3 |
| SYCP2 | ZNF830 | 0.697319 | 3 | 0 | 3 |
| SYCP2 | PDRG1 | 0.69356 | 3 | 0 | 3 |
| SYCP2 | SLC2A4RG | 0.688331 | 3 | 0 | 3 |
| SYCP2 | ABCA12 | 0.687555 | 3 | 0 | 3 |
| SYCP2 | PDP1 | 0.686973 | 3 | 0 | 3 |
| SYCP2 | WDR5 | 0.686728 | 4 | 0 | 3 |
| SYCP2 | NSUN2 | 0.685654 | 3 | 0 | 3 |
| SYCP2 | PNLDC1 | 0.683351 | 3 | 0 | 3 |
| SYCP2 | ACVR1C | 0.679271 | 4 | 0 | 3 |
| SYCP2 | UTP23 | 0.676069 | 4 | 0 | 3 |
| SYCP2 | DDX55 | 0.674299 | 5 | 0 | 4 |
For details and further investigation, click here
