| Full name: transmembrane protein 120A | Alias Symbol: TMPIT|NET29 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 83862 | HGNC ID: HGNC:21697 | Ensembl Gene: ENSG00000189077 | OMIM ID: 616550 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM120A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM120A | 83862 | 223482_at | -0.1782 | 0.7541 | |
| GSE26886 | TMEM120A | 83862 | 223482_at | -0.6453 | 0.0000 | |
| GSE45670 | TMEM120A | 83862 | 223482_at | -0.3853 | 0.0043 | |
| GSE53622 | TMEM120A | 83862 | 22740 | -0.9121 | 0.0000 | |
| GSE53624 | TMEM120A | 83862 | 22740 | -0.9595 | 0.0000 | |
| GSE63941 | TMEM120A | 83862 | 223482_at | -1.1903 | 0.0178 | |
| GSE77861 | TMEM120A | 83862 | 223482_at | -0.7470 | 0.0087 | |
| GSE97050 | TMEM120A | 83862 | A_23_P259632 | -0.1834 | 0.3989 | |
| SRP007169 | TMEM120A | 83862 | RNAseq | -2.5976 | 0.0000 | |
| SRP008496 | TMEM120A | 83862 | RNAseq | -2.0567 | 0.0000 | |
| SRP064894 | TMEM120A | 83862 | RNAseq | -0.4181 | 0.1550 | |
| SRP133303 | TMEM120A | 83862 | RNAseq | -0.8546 | 0.0000 | |
| SRP159526 | TMEM120A | 83862 | RNAseq | -1.1633 | 0.0000 | |
| SRP193095 | TMEM120A | 83862 | RNAseq | -0.9434 | 0.0000 | |
| SRP219564 | TMEM120A | 83862 | RNAseq | -0.4280 | 0.1926 | |
| TCGA | TMEM120A | 83862 | RNAseq | -0.2602 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TMEM120A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM120A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM120A | 83862 | 14 | 1 | 15 | |
| GSE20123 | TMEM120A | 83862 | 14 | 1 | 15 | |
| GSE43470 | TMEM120A | 83862 | 3 | 2 | 38 | |
| GSE46452 | TMEM120A | 83862 | 12 | 0 | 47 | |
| GSE47630 | TMEM120A | 83862 | 7 | 2 | 31 | |
| GSE54993 | TMEM120A | 83862 | 2 | 7 | 61 | |
| GSE54994 | TMEM120A | 83862 | 14 | 3 | 36 | |
| GSE60625 | TMEM120A | 83862 | 0 | 0 | 11 | |
| GSE74703 | TMEM120A | 83862 | 3 | 1 | 32 | |
| GSE74704 | TMEM120A | 83862 | 8 | 1 | 11 | |
| TCGA | TMEM120A | 83862 | 44 | 5 | 47 |
Total number of gains: 121; Total number of losses: 23; Total Number of normals: 344.
Somatic mutations of TMEM120A:
Generating mutation plots.
Highly correlated genes for TMEM120A:
Showing top 20/1369 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM120A | PIK3CB | 0.807836 | 3 | 0 | 3 |
| TMEM120A | OSBPL8 | 0.778199 | 3 | 0 | 3 |
| TMEM120A | MTF1 | 0.772341 | 6 | 0 | 6 |
| TMEM120A | DUSP22 | 0.771069 | 6 | 0 | 6 |
| TMEM120A | GPR108 | 0.76652 | 3 | 0 | 3 |
| TMEM120A | HBP1 | 0.758756 | 4 | 0 | 4 |
| TMEM120A | CCNDBP1 | 0.758001 | 5 | 0 | 5 |
| TMEM120A | RABEP2 | 0.757669 | 4 | 0 | 4 |
| TMEM120A | TBC1D22B | 0.755702 | 6 | 0 | 5 |
| TMEM120A | GGA3 | 0.752348 | 5 | 0 | 5 |
| TMEM120A | BLVRB | 0.750708 | 5 | 0 | 5 |
| TMEM120A | PLEKHA7 | 0.750591 | 7 | 0 | 7 |
| TMEM120A | APEH | 0.747048 | 5 | 0 | 5 |
| TMEM120A | CHCHD1 | 0.746645 | 4 | 0 | 4 |
| TMEM120A | ZFAND2B | 0.746249 | 8 | 0 | 7 |
| TMEM120A | ARHGEF6 | 0.741487 | 3 | 0 | 3 |
| TMEM120A | RAB5B | 0.738501 | 7 | 0 | 6 |
| TMEM120A | SETD4 | 0.737991 | 3 | 0 | 3 |
| TMEM120A | MFSD6 | 0.736825 | 6 | 0 | 6 |
| TMEM120A | ZNF93 | 0.73485 | 3 | 0 | 3 |
For details and further investigation, click here
