| Full name: zinc finger protein 175 | Alias Symbol: OTK18 | ||
| Type: protein-coding gene | Cytoband: 19q13.41 | ||
| Entrez ID: 7728 | HGNC ID: HGNC:12964 | Ensembl Gene: ENSG00000105497 | OMIM ID: 601139 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF175:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF175 | 7728 | 205497_at | -0.3015 | 0.5562 | |
| GSE20347 | ZNF175 | 7728 | 205497_at | 0.0060 | 0.9448 | |
| GSE23400 | ZNF175 | 7728 | 205497_at | 0.0581 | 0.2173 | |
| GSE26886 | ZNF175 | 7728 | 205497_at | -0.9121 | 0.0002 | |
| GSE29001 | ZNF175 | 7728 | 205497_at | -0.0480 | 0.8873 | |
| GSE38129 | ZNF175 | 7728 | 205497_at | -0.0445 | 0.6948 | |
| GSE45670 | ZNF175 | 7728 | 205497_at | -0.1284 | 0.4337 | |
| GSE53622 | ZNF175 | 7728 | 55539 | -0.1777 | 0.0266 | |
| GSE53624 | ZNF175 | 7728 | 55539 | 0.0291 | 0.6923 | |
| GSE63941 | ZNF175 | 7728 | 205497_at | -0.7074 | 0.1629 | |
| GSE77861 | ZNF175 | 7728 | 205497_at | -0.2035 | 0.0877 | |
| GSE97050 | ZNF175 | 7728 | A_23_P332374 | -0.0906 | 0.6431 | |
| SRP007169 | ZNF175 | 7728 | RNAseq | 0.1003 | 0.8841 | |
| SRP008496 | ZNF175 | 7728 | RNAseq | 0.1634 | 0.6964 | |
| SRP064894 | ZNF175 | 7728 | RNAseq | 0.0059 | 0.9750 | |
| SRP133303 | ZNF175 | 7728 | RNAseq | -0.3389 | 0.0959 | |
| SRP159526 | ZNF175 | 7728 | RNAseq | -0.1020 | 0.7786 | |
| SRP193095 | ZNF175 | 7728 | RNAseq | -0.2860 | 0.0993 | |
| SRP219564 | ZNF175 | 7728 | RNAseq | -0.5120 | 0.0801 | |
| TCGA | ZNF175 | 7728 | RNAseq | -0.4387 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF175 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF175:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF175 | 7728 | 3 | 4 | 23 | |
| GSE20123 | ZNF175 | 7728 | 3 | 3 | 24 | |
| GSE43470 | ZNF175 | 7728 | 3 | 12 | 28 | |
| GSE46452 | ZNF175 | 7728 | 45 | 1 | 13 | |
| GSE47630 | ZNF175 | 7728 | 10 | 6 | 24 | |
| GSE54993 | ZNF175 | 7728 | 17 | 4 | 49 | |
| GSE54994 | ZNF175 | 7728 | 4 | 14 | 35 | |
| GSE60625 | ZNF175 | 7728 | 9 | 0 | 2 | |
| GSE74703 | ZNF175 | 7728 | 3 | 8 | 25 | |
| GSE74704 | ZNF175 | 7728 | 3 | 1 | 16 | |
| TCGA | ZNF175 | 7728 | 14 | 19 | 63 |
Total number of gains: 114; Total number of losses: 72; Total Number of normals: 302.
Somatic mutations of ZNF175:
Generating mutation plots.
Highly correlated genes for ZNF175:
Showing top 20/482 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF175 | TRIM6 | 0.81081 | 3 | 0 | 3 |
| ZNF175 | WASF2 | 0.809468 | 3 | 0 | 3 |
| ZNF175 | SLC12A6 | 0.788726 | 3 | 0 | 3 |
| ZNF175 | CPEB4 | 0.77965 | 3 | 0 | 3 |
| ZNF175 | MFSD5 | 0.778461 | 3 | 0 | 3 |
| ZNF175 | TBC1D22B | 0.777519 | 3 | 0 | 3 |
| ZNF175 | PEX11B | 0.775625 | 3 | 0 | 3 |
| ZNF175 | RABGAP1 | 0.766558 | 3 | 0 | 3 |
| ZNF175 | MTMR3 | 0.766264 | 3 | 0 | 3 |
| ZNF175 | FAM174A | 0.759284 | 3 | 0 | 3 |
| ZNF175 | ACVR1B | 0.755999 | 3 | 0 | 3 |
| ZNF175 | CCL28 | 0.754542 | 3 | 0 | 3 |
| ZNF175 | TLE2 | 0.751044 | 3 | 0 | 3 |
| ZNF175 | RORA | 0.746278 | 3 | 0 | 3 |
| ZNF175 | RHBDF1 | 0.744451 | 3 | 0 | 3 |
| ZNF175 | EMP2 | 0.743354 | 3 | 0 | 3 |
| ZNF175 | PRADC1 | 0.739861 | 3 | 0 | 3 |
| ZNF175 | APEH | 0.739534 | 3 | 0 | 3 |
| ZNF175 | TOM1 | 0.738494 | 3 | 0 | 3 |
| ZNF175 | KLF3 | 0.732128 | 3 | 0 | 3 |
For details and further investigation, click here
