| Full name: UTP3 small subunit processome component | Alias Symbol: FLJ23256|DKFZp761F222|SAS10|CRLZ1 | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 57050 | HGNC ID: HGNC:24477 | Ensembl Gene: ENSG00000132467 | OMIM ID: 611614 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UTP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UTP3 | 57050 | 209486_at | 0.1890 | 0.6051 | |
| GSE20347 | UTP3 | 57050 | 209486_at | -0.4317 | 0.0035 | |
| GSE23400 | UTP3 | 57050 | 209486_at | 0.1161 | 0.2043 | |
| GSE26886 | UTP3 | 57050 | 209486_at | -0.0678 | 0.7562 | |
| GSE29001 | UTP3 | 57050 | 209486_at | -0.2391 | 0.6659 | |
| GSE38129 | UTP3 | 57050 | 209486_at | -0.1508 | 0.3054 | |
| GSE45670 | UTP3 | 57050 | 209486_at | -0.1934 | 0.1802 | |
| GSE53622 | UTP3 | 57050 | 15474 | -0.3289 | 0.0000 | |
| GSE53624 | UTP3 | 57050 | 15474 | -0.3200 | 0.0000 | |
| GSE63941 | UTP3 | 57050 | 209486_at | -1.0255 | 0.0225 | |
| GSE77861 | UTP3 | 57050 | 209486_at | -0.1018 | 0.7201 | |
| GSE97050 | UTP3 | 57050 | A_23_P92424 | -0.2378 | 0.3384 | |
| SRP007169 | UTP3 | 57050 | RNAseq | 0.0295 | 0.9431 | |
| SRP008496 | UTP3 | 57050 | RNAseq | -0.0035 | 0.9918 | |
| SRP064894 | UTP3 | 57050 | RNAseq | -0.3073 | 0.0428 | |
| SRP133303 | UTP3 | 57050 | RNAseq | -0.1396 | 0.3325 | |
| SRP159526 | UTP3 | 57050 | RNAseq | -0.4293 | 0.0507 | |
| SRP193095 | UTP3 | 57050 | RNAseq | -0.3084 | 0.0014 | |
| SRP219564 | UTP3 | 57050 | RNAseq | -0.7178 | 0.0008 | |
| TCGA | UTP3 | 57050 | RNAseq | -0.0189 | 0.7287 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UTP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UTP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UTP3 | 57050 | 0 | 11 | 19 | |
| GSE20123 | UTP3 | 57050 | 0 | 11 | 19 | |
| GSE43470 | UTP3 | 57050 | 0 | 13 | 30 | |
| GSE46452 | UTP3 | 57050 | 2 | 35 | 22 | |
| GSE47630 | UTP3 | 57050 | 1 | 19 | 20 | |
| GSE54993 | UTP3 | 57050 | 7 | 0 | 63 | |
| GSE54994 | UTP3 | 57050 | 1 | 9 | 43 | |
| GSE60625 | UTP3 | 57050 | 0 | 0 | 11 | |
| GSE74703 | UTP3 | 57050 | 0 | 11 | 25 | |
| GSE74704 | UTP3 | 57050 | 0 | 6 | 14 | |
| TCGA | UTP3 | 57050 | 16 | 28 | 52 |
Total number of gains: 27; Total number of losses: 143; Total Number of normals: 318.
Somatic mutations of UTP3:
Generating mutation plots.
Highly correlated genes for UTP3:
Showing top 20/380 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UTP3 | CDC73 | 0.799656 | 3 | 0 | 3 |
| UTP3 | MRPL1 | 0.795486 | 4 | 0 | 4 |
| UTP3 | KDM2B | 0.778265 | 3 | 0 | 3 |
| UTP3 | RB1CC1 | 0.768731 | 3 | 0 | 3 |
| UTP3 | PAK1IP1 | 0.762187 | 3 | 0 | 3 |
| UTP3 | UBE2W | 0.760739 | 4 | 0 | 4 |
| UTP3 | TBC1D22B | 0.753567 | 3 | 0 | 3 |
| UTP3 | DYRK2 | 0.751675 | 3 | 0 | 3 |
| UTP3 | TFIP11 | 0.748879 | 3 | 0 | 3 |
| UTP3 | AHCY | 0.737438 | 3 | 0 | 3 |
| UTP3 | ATP11B | 0.730512 | 3 | 0 | 3 |
| UTP3 | YY1 | 0.729165 | 3 | 0 | 3 |
| UTP3 | ZFAND1 | 0.727147 | 3 | 0 | 3 |
| UTP3 | RASA2 | 0.722663 | 3 | 0 | 3 |
| UTP3 | THUMPD1 | 0.705876 | 4 | 0 | 4 |
| UTP3 | DOK1 | 0.704654 | 3 | 0 | 3 |
| UTP3 | MGAT5 | 0.702767 | 3 | 0 | 3 |
| UTP3 | ZNF276 | 0.699873 | 3 | 0 | 3 |
| UTP3 | LY75 | 0.698895 | 4 | 0 | 3 |
| UTP3 | EIF3M | 0.698472 | 4 | 0 | 4 |
For details and further investigation, click here
