| Full name: tandem C2 domains, nuclear | Alias Symbol: FLJ36557|Tac2-N|C2CD1 | ||
| Type: protein-coding gene | Cytoband: 14q32.12 | ||
| Entrez ID: 123036 | HGNC ID: HGNC:19859 | Ensembl Gene: ENSG00000165929 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TC2N:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TC2N | 123036 | 1553132_a_at | -0.2377 | 0.8159 | |
| GSE26886 | TC2N | 123036 | 234970_at | -0.7669 | 0.0042 | |
| GSE45670 | TC2N | 123036 | 1553132_a_at | 0.0068 | 0.9866 | |
| GSE53622 | TC2N | 123036 | 60147 | -1.1026 | 0.0000 | |
| GSE53624 | TC2N | 123036 | 60147 | -1.1289 | 0.0000 | |
| GSE63941 | TC2N | 123036 | 1553132_a_at | 2.9139 | 0.0139 | |
| GSE77861 | TC2N | 123036 | 234970_at | -0.4029 | 0.0660 | |
| GSE97050 | TC2N | 123036 | A_33_P3378665 | -0.3390 | 0.5560 | |
| SRP007169 | TC2N | 123036 | RNAseq | -2.8776 | 0.0000 | |
| SRP008496 | TC2N | 123036 | RNAseq | -1.9866 | 0.0000 | |
| SRP064894 | TC2N | 123036 | RNAseq | -1.4075 | 0.0004 | |
| SRP133303 | TC2N | 123036 | RNAseq | -0.6934 | 0.0020 | |
| SRP159526 | TC2N | 123036 | RNAseq | -1.1520 | 0.0000 | |
| SRP193095 | TC2N | 123036 | RNAseq | -0.9345 | 0.0000 | |
| SRP219564 | TC2N | 123036 | RNAseq | -0.2371 | 0.7500 | |
| TCGA | TC2N | 123036 | RNAseq | -0.2588 | 0.0182 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by TC2N expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TC2N:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TC2N | 123036 | 9 | 5 | 16 | |
| GSE20123 | TC2N | 123036 | 9 | 4 | 17 | |
| GSE43470 | TC2N | 123036 | 7 | 3 | 33 | |
| GSE46452 | TC2N | 123036 | 16 | 3 | 40 | |
| GSE47630 | TC2N | 123036 | 11 | 8 | 21 | |
| GSE54993 | TC2N | 123036 | 3 | 8 | 59 | |
| GSE54994 | TC2N | 123036 | 20 | 4 | 29 | |
| GSE60625 | TC2N | 123036 | 0 | 2 | 9 | |
| GSE74703 | TC2N | 123036 | 6 | 3 | 27 | |
| GSE74704 | TC2N | 123036 | 4 | 3 | 13 | |
| TCGA | TC2N | 123036 | 30 | 21 | 45 |
Total number of gains: 115; Total number of losses: 64; Total Number of normals: 309.
Somatic mutations of TC2N:
Generating mutation plots.
Highly correlated genes for TC2N:
Showing top 20/474 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TC2N | MAP4K5 | 0.735122 | 3 | 0 | 3 |
| TC2N | ZNF165 | 0.704095 | 4 | 0 | 4 |
| TC2N | CPT2 | 0.696773 | 4 | 0 | 4 |
| TC2N | UBE2V2 | 0.69371 | 3 | 0 | 3 |
| TC2N | ZFYVE26 | 0.692453 | 3 | 0 | 3 |
| TC2N | ACSL3 | 0.691654 | 4 | 0 | 3 |
| TC2N | ZNF570 | 0.691633 | 3 | 0 | 3 |
| TC2N | ZNF675 | 0.684311 | 3 | 0 | 3 |
| TC2N | EPB41L5 | 0.683991 | 5 | 0 | 5 |
| TC2N | TSEN2 | 0.682738 | 3 | 0 | 3 |
| TC2N | RBM27 | 0.681429 | 3 | 0 | 3 |
| TC2N | AK4 | 0.675527 | 5 | 0 | 5 |
| TC2N | CREB1 | 0.674088 | 3 | 0 | 3 |
| TC2N | B4GALT5 | 0.671998 | 3 | 0 | 3 |
| TC2N | SNW1 | 0.671443 | 4 | 0 | 3 |
| TC2N | UBE2E2 | 0.670352 | 4 | 0 | 4 |
| TC2N | ST3GAL6 | 0.670083 | 3 | 0 | 3 |
| TC2N | C1orf56 | 0.663816 | 3 | 0 | 3 |
| TC2N | GTF3C6 | 0.660761 | 3 | 0 | 3 |
| TC2N | SH3YL1 | 0.656297 | 5 | 0 | 3 |
For details and further investigation, click here
