| Full name: carnitine palmitoyltransferase 2 | Alias Symbol: CPTASE | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 1376 | HGNC ID: HGNC:2330 | Ensembl Gene: ENSG00000157184 | OMIM ID: 600650 |
| Drug and gene relationship at DGIdb | |||
CPT2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03320 | PPAR signaling pathway |
Expression of CPT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPT2 | 1376 | 204263_s_at | -0.6636 | 0.2385 | |
| GSE20347 | CPT2 | 1376 | 204264_at | -0.7305 | 0.0000 | |
| GSE23400 | CPT2 | 1376 | 204263_s_at | -0.2638 | 0.0000 | |
| GSE26886 | CPT2 | 1376 | 204264_at | -1.1656 | 0.0001 | |
| GSE29001 | CPT2 | 1376 | 204264_at | -0.8430 | 0.0184 | |
| GSE38129 | CPT2 | 1376 | 204264_at | -0.4622 | 0.0029 | |
| GSE45670 | CPT2 | 1376 | 204264_at | -0.2233 | 0.2713 | |
| GSE63941 | CPT2 | 1376 | 204263_s_at | 0.6763 | 0.0311 | |
| GSE77861 | CPT2 | 1376 | 204264_at | -0.5587 | 0.0477 | |
| GSE97050 | CPT2 | 1376 | A_23_P148919 | 0.0449 | 0.8336 | |
| SRP007169 | CPT2 | 1376 | RNAseq | -0.7971 | 0.0585 | |
| SRP008496 | CPT2 | 1376 | RNAseq | -0.9690 | 0.0000 | |
| SRP064894 | CPT2 | 1376 | RNAseq | -0.4550 | 0.0013 | |
| SRP133303 | CPT2 | 1376 | RNAseq | -0.3638 | 0.0510 | |
| SRP159526 | CPT2 | 1376 | RNAseq | -0.7115 | 0.0175 | |
| SRP193095 | CPT2 | 1376 | RNAseq | -0.7814 | 0.0000 | |
| SRP219564 | CPT2 | 1376 | RNAseq | -0.5837 | 0.0707 | |
| TCGA | CPT2 | 1376 | RNAseq | -0.2553 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CPT2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CPT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPT2 | 1376 | 3 | 4 | 23 | |
| GSE20123 | CPT2 | 1376 | 3 | 3 | 24 | |
| GSE43470 | CPT2 | 1376 | 6 | 2 | 35 | |
| GSE46452 | CPT2 | 1376 | 2 | 1 | 56 | |
| GSE47630 | CPT2 | 1376 | 8 | 4 | 28 | |
| GSE54993 | CPT2 | 1376 | 0 | 1 | 69 | |
| GSE54994 | CPT2 | 1376 | 11 | 2 | 40 | |
| GSE60625 | CPT2 | 1376 | 0 | 0 | 11 | |
| GSE74703 | CPT2 | 1376 | 4 | 1 | 31 | |
| GSE74704 | CPT2 | 1376 | 2 | 0 | 18 | |
| TCGA | CPT2 | 1376 | 10 | 19 | 67 |
Total number of gains: 49; Total number of losses: 37; Total Number of normals: 402.
Somatic mutations of CPT2:
Generating mutation plots.
Highly correlated genes for CPT2:
Showing top 20/1272 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPT2 | IMPACT | 0.859448 | 3 | 0 | 3 |
| CPT2 | VPS25 | 0.798289 | 3 | 0 | 3 |
| CPT2 | HDHD2 | 0.795785 | 3 | 0 | 3 |
| CPT2 | FAM122A | 0.78116 | 3 | 0 | 3 |
| CPT2 | FGD4 | 0.770556 | 3 | 0 | 3 |
| CPT2 | KDM3B | 0.762373 | 3 | 0 | 3 |
| CPT2 | FAR1 | 0.757698 | 4 | 0 | 4 |
| CPT2 | ARRDC3 | 0.754919 | 5 | 0 | 5 |
| CPT2 | SUPT4H1 | 0.752769 | 3 | 0 | 3 |
| CPT2 | ZNF823 | 0.751271 | 5 | 0 | 5 |
| CPT2 | FAM174A | 0.740914 | 4 | 0 | 4 |
| CPT2 | TET2 | 0.739921 | 4 | 0 | 3 |
| CPT2 | KAT7 | 0.739482 | 3 | 0 | 3 |
| CPT2 | PRELID1 | 0.735341 | 3 | 0 | 3 |
| CPT2 | ATF1 | 0.734969 | 3 | 0 | 3 |
| CPT2 | WDR11 | 0.733738 | 3 | 0 | 3 |
| CPT2 | ZNF70 | 0.733709 | 3 | 0 | 3 |
| CPT2 | RASSF5 | 0.731893 | 5 | 0 | 5 |
| CPT2 | TMEM161B | 0.729367 | 4 | 0 | 4 |
| CPT2 | FBXW5 | 0.726972 | 3 | 0 | 3 |
For details and further investigation, click here
