| Full name: SH3 and SYLF domain containing 1 | Alias Symbol: Ray|DKFZP586F1318 | ||
| Type: protein-coding gene | Cytoband: 2p25.3 | ||
| Entrez ID: 26751 | HGNC ID: HGNC:29546 | Ensembl Gene: ENSG00000035115 | OMIM ID: 617314 |
| Drug and gene relationship at DGIdb | |||
Expression of SH3YL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SH3YL1 | 26751 | 204019_s_at | -0.4354 | 0.5396 | |
| GSE20347 | SH3YL1 | 26751 | 204019_s_at | -1.1672 | 0.0005 | |
| GSE23400 | SH3YL1 | 26751 | 204019_s_at | -0.8718 | 0.0000 | |
| GSE26886 | SH3YL1 | 26751 | 204019_s_at | -0.5509 | 0.1044 | |
| GSE29001 | SH3YL1 | 26751 | 204019_s_at | -0.8668 | 0.0395 | |
| GSE38129 | SH3YL1 | 26751 | 204019_s_at | -0.7161 | 0.0382 | |
| GSE45670 | SH3YL1 | 26751 | 204019_s_at | -0.3889 | 0.2140 | |
| GSE53622 | SH3YL1 | 26751 | 29276 | -0.9968 | 0.0000 | |
| GSE53624 | SH3YL1 | 26751 | 29276 | -1.3696 | 0.0000 | |
| GSE63941 | SH3YL1 | 26751 | 204019_s_at | -0.2370 | 0.9204 | |
| GSE77861 | SH3YL1 | 26751 | 204019_s_at | -0.8646 | 0.0032 | |
| GSE97050 | SH3YL1 | 26751 | A_33_P3379456 | -0.3425 | 0.3437 | |
| SRP007169 | SH3YL1 | 26751 | RNAseq | -2.7474 | 0.0000 | |
| SRP008496 | SH3YL1 | 26751 | RNAseq | -1.9841 | 0.0000 | |
| SRP064894 | SH3YL1 | 26751 | RNAseq | -1.3091 | 0.0000 | |
| SRP133303 | SH3YL1 | 26751 | RNAseq | -1.0021 | 0.0000 | |
| SRP159526 | SH3YL1 | 26751 | RNAseq | -1.0709 | 0.0012 | |
| SRP193095 | SH3YL1 | 26751 | RNAseq | -1.2837 | 0.0000 | |
| SRP219564 | SH3YL1 | 26751 | RNAseq | -0.7549 | 0.2890 | |
| TCGA | SH3YL1 | 26751 | RNAseq | -0.3393 | 0.0010 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by SH3YL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SH3YL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SH3YL1 | 26751 | 8 | 2 | 20 | |
| GSE20123 | SH3YL1 | 26751 | 8 | 2 | 20 | |
| GSE43470 | SH3YL1 | 26751 | 2 | 2 | 39 | |
| GSE46452 | SH3YL1 | 26751 | 3 | 4 | 52 | |
| GSE47630 | SH3YL1 | 26751 | 7 | 0 | 33 | |
| GSE54993 | SH3YL1 | 26751 | 1 | 7 | 62 | |
| GSE54994 | SH3YL1 | 26751 | 13 | 0 | 40 | |
| GSE60625 | SH3YL1 | 26751 | 0 | 3 | 8 | |
| GSE74703 | SH3YL1 | 26751 | 2 | 0 | 34 | |
| GSE74704 | SH3YL1 | 26751 | 8 | 1 | 11 | |
| TCGA | SH3YL1 | 26751 | 32 | 5 | 59 |
Total number of gains: 84; Total number of losses: 26; Total Number of normals: 378.
Somatic mutations of SH3YL1:
Generating mutation plots.
Highly correlated genes for SH3YL1:
Showing top 20/1035 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SH3YL1 | ING2 | 0.740786 | 3 | 0 | 3 |
| SH3YL1 | MPZL3 | 0.711978 | 4 | 0 | 4 |
| SH3YL1 | NIPAL1 | 0.706443 | 3 | 0 | 3 |
| SH3YL1 | SLC10A5 | 0.69256 | 3 | 0 | 3 |
| SH3YL1 | CCDC7 | 0.686617 | 3 | 0 | 3 |
| SH3YL1 | DDI2 | 0.68176 | 3 | 0 | 3 |
| SH3YL1 | LTA4H | 0.681745 | 3 | 0 | 3 |
| SH3YL1 | ANKRD31 | 0.678101 | 4 | 0 | 4 |
| SH3YL1 | BRWD1 | 0.675627 | 4 | 0 | 3 |
| SH3YL1 | CA13 | 0.673164 | 3 | 0 | 3 |
| SH3YL1 | NPAS2 | 0.668415 | 6 | 0 | 6 |
| SH3YL1 | TRAPPC13 | 0.66189 | 5 | 0 | 4 |
| SH3YL1 | ATP6V1G1 | 0.659242 | 4 | 0 | 3 |
| SH3YL1 | GOLGA5 | 0.658152 | 3 | 0 | 3 |
| SH3YL1 | TC2N | 0.656297 | 5 | 0 | 3 |
| SH3YL1 | TRNAU1AP | 0.652266 | 4 | 0 | 4 |
| SH3YL1 | SLMAP | 0.650336 | 3 | 0 | 3 |
| SH3YL1 | TRIM5 | 0.646482 | 4 | 0 | 3 |
| SH3YL1 | NUAK2 | 0.646441 | 3 | 0 | 3 |
| SH3YL1 | SS18 | 0.645639 | 4 | 0 | 3 |
For details and further investigation, click here
