| Full name: transcription factor 15 | Alias Symbol: EC2|PARAXIS|bHLHa40 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 6939 | HGNC ID: HGNC:11627 | Ensembl Gene: ENSG00000125878 | OMIM ID: 601010 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TCF15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TCF15 | 6939 | 207306_at | 0.2123 | 0.4436 | |
| GSE20347 | TCF15 | 6939 | 207306_at | 0.0731 | 0.6421 | |
| GSE23400 | TCF15 | 6939 | 207306_at | -0.1121 | 0.0153 | |
| GSE26886 | TCF15 | 6939 | 207306_at | 0.9569 | 0.0001 | |
| GSE29001 | TCF15 | 6939 | 207306_at | -0.1438 | 0.2981 | |
| GSE38129 | TCF15 | 6939 | 207306_at | 0.0353 | 0.8554 | |
| GSE45670 | TCF15 | 6939 | 207306_at | -0.0597 | 0.7390 | |
| GSE63941 | TCF15 | 6939 | 207306_at | 0.9128 | 0.0085 | |
| GSE77861 | TCF15 | 6939 | 207306_at | -0.0940 | 0.7542 | |
| GSE97050 | TCF15 | 6939 | A_23_P254816 | -0.1898 | 0.5244 | |
| SRP219564 | TCF15 | 6939 | RNAseq | 1.3641 | 0.0793 | |
| TCGA | TCF15 | 6939 | RNAseq | 1.9981 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TCF15 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TCF15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TCF15 | 6939 | 12 | 4 | 14 | |
| GSE20123 | TCF15 | 6939 | 13 | 4 | 13 | |
| GSE43470 | TCF15 | 6939 | 11 | 1 | 31 | |
| GSE46452 | TCF15 | 6939 | 26 | 1 | 32 | |
| GSE47630 | TCF15 | 6939 | 19 | 4 | 17 | |
| GSE54993 | TCF15 | 6939 | 2 | 15 | 53 | |
| GSE54994 | TCF15 | 6939 | 24 | 2 | 27 | |
| GSE60625 | TCF15 | 6939 | 0 | 0 | 11 | |
| GSE74703 | TCF15 | 6939 | 10 | 1 | 25 | |
| GSE74704 | TCF15 | 6939 | 8 | 2 | 10 | |
| TCGA | TCF15 | 6939 | 41 | 11 | 44 |
Total number of gains: 166; Total number of losses: 45; Total Number of normals: 277.
Somatic mutations of TCF15:
Generating mutation plots.
Highly correlated genes for TCF15:
Showing top 20/370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TCF15 | GAS6-AS1 | 0.788757 | 3 | 0 | 3 |
| TCF15 | ACAP1 | 0.734542 | 3 | 0 | 3 |
| TCF15 | BLOC1S3 | 0.730324 | 3 | 0 | 3 |
| TCF15 | ZNF628 | 0.726158 | 3 | 0 | 3 |
| TCF15 | TBC1D25 | 0.717215 | 3 | 0 | 3 |
| TCF15 | MYPOP | 0.711461 | 3 | 0 | 3 |
| TCF15 | TNRC6C | 0.705396 | 3 | 0 | 3 |
| TCF15 | SCUBE1 | 0.700783 | 3 | 0 | 3 |
| TCF15 | SLC13A2 | 0.694452 | 4 | 0 | 4 |
| TCF15 | IL34 | 0.690469 | 4 | 0 | 4 |
| TCF15 | GOSR1 | 0.689889 | 3 | 0 | 3 |
| TCF15 | ELAVL3 | 0.685706 | 9 | 0 | 9 |
| TCF15 | ZNF683 | 0.684034 | 4 | 0 | 4 |
| TCF15 | TEAD3 | 0.673945 | 3 | 0 | 3 |
| TCF15 | PGM5 | 0.673729 | 3 | 0 | 3 |
| TCF15 | PRR12 | 0.670255 | 4 | 0 | 4 |
| TCF15 | FOXC1 | 0.669197 | 3 | 0 | 3 |
| TCF15 | SHISA4 | 0.666798 | 3 | 0 | 3 |
| TCF15 | GLDN | 0.666529 | 3 | 0 | 3 |
| TCF15 | TMEM151A | 0.665825 | 3 | 0 | 3 |
For details and further investigation, click here
