| Full name: shisa family member 4 | Alias Symbol: hShisa4 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 149345 | HGNC ID: HGNC:27139 | Ensembl Gene: ENSG00000198892 | OMIM ID: 617326 |
| Drug and gene relationship at DGIdb | |||
Expression of SHISA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SHISA4 | 149345 | 226674_at | -0.0069 | 0.9882 | |
| GSE26886 | SHISA4 | 149345 | 226674_at | 0.7321 | 0.0001 | |
| GSE45670 | SHISA4 | 149345 | 226674_at | -0.0211 | 0.8935 | |
| GSE53622 | SHISA4 | 149345 | 106378 | -0.1124 | 0.1810 | |
| GSE53624 | SHISA4 | 149345 | 106378 | -0.4107 | 0.0000 | |
| GSE63941 | SHISA4 | 149345 | 226674_at | -0.6888 | 0.0826 | |
| GSE77861 | SHISA4 | 149345 | 226674_at | 0.1289 | 0.4572 | |
| GSE97050 | SHISA4 | 149345 | A_23_P115573 | -0.4300 | 0.1636 | |
| SRP007169 | SHISA4 | 149345 | RNAseq | 1.7534 | 0.0696 | |
| SRP064894 | SHISA4 | 149345 | RNAseq | 0.8739 | 0.0289 | |
| SRP133303 | SHISA4 | 149345 | RNAseq | 0.4001 | 0.1696 | |
| SRP159526 | SHISA4 | 149345 | RNAseq | 1.0838 | 0.0041 | |
| SRP219564 | SHISA4 | 149345 | RNAseq | 0.3621 | 0.6093 | |
| TCGA | SHISA4 | 149345 | RNAseq | -0.1015 | 0.5169 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SHISA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SHISA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SHISA4 | 149345 | 11 | 0 | 19 | |
| GSE20123 | SHISA4 | 149345 | 11 | 0 | 19 | |
| GSE43470 | SHISA4 | 149345 | 6 | 0 | 37 | |
| GSE46452 | SHISA4 | 149345 | 3 | 1 | 55 | |
| GSE47630 | SHISA4 | 149345 | 14 | 0 | 26 | |
| GSE54993 | SHISA4 | 149345 | 0 | 6 | 64 | |
| GSE54994 | SHISA4 | 149345 | 15 | 0 | 38 | |
| GSE60625 | SHISA4 | 149345 | 0 | 0 | 11 | |
| GSE74703 | SHISA4 | 149345 | 6 | 0 | 30 | |
| GSE74704 | SHISA4 | 149345 | 5 | 0 | 15 | |
| TCGA | SHISA4 | 149345 | 43 | 5 | 48 |
Total number of gains: 114; Total number of losses: 12; Total Number of normals: 362.
Somatic mutations of SHISA4:
Generating mutation plots.
Highly correlated genes for SHISA4:
Showing top 20/313 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SHISA4 | PHF1 | 0.791433 | 3 | 0 | 3 |
| SHISA4 | HSD17B14 | 0.783742 | 3 | 0 | 3 |
| SHISA4 | MAPK8IP2 | 0.780631 | 3 | 0 | 3 |
| SHISA4 | PSPN | 0.753718 | 3 | 0 | 3 |
| SHISA4 | EBF4 | 0.752219 | 3 | 0 | 3 |
| SHISA4 | FAM181B | 0.748949 | 3 | 0 | 3 |
| SHISA4 | SHC2 | 0.748447 | 4 | 0 | 4 |
| SHISA4 | TRIM17 | 0.733314 | 3 | 0 | 3 |
| SHISA4 | MGAT5B | 0.731729 | 4 | 0 | 4 |
| SHISA4 | CDH23 | 0.730417 | 3 | 0 | 3 |
| SHISA4 | KIRREL2 | 0.730199 | 5 | 0 | 5 |
| SHISA4 | DUSP9 | 0.728727 | 3 | 0 | 3 |
| SHISA4 | SLC22A31 | 0.727757 | 3 | 0 | 3 |
| SHISA4 | ZNF428 | 0.727189 | 5 | 0 | 4 |
| SHISA4 | PRRT2 | 0.723004 | 4 | 0 | 4 |
| SHISA4 | SLC29A4 | 0.72139 | 3 | 0 | 3 |
| SHISA4 | VCX2 | 0.720059 | 3 | 0 | 3 |
| SHISA4 | NRXN1 | 0.716974 | 3 | 0 | 3 |
| SHISA4 | RASL10B | 0.71599 | 5 | 0 | 5 |
| SHISA4 | LTB4R2 | 0.707312 | 3 | 0 | 3 |
For details and further investigation, click here
