| Full name: trinucleotide repeat containing adaptor 6C | Alias Symbol: KIAA1582|FLJ20015 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 57690 | HGNC ID: HGNC:29318 | Ensembl Gene: ENSG00000078687 | OMIM ID: 610741 |
| Drug and gene relationship at DGIdb | |||
Expression of TNRC6C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNRC6C | 57690 | 222820_at | -0.3912 | 0.6630 | |
| GSE26886 | TNRC6C | 57690 | 242314_at | 0.2510 | 0.0045 | |
| GSE45670 | TNRC6C | 57690 | 222820_at | -0.7144 | 0.0053 | |
| GSE53622 | TNRC6C | 57690 | 52281 | -0.0461 | 0.6932 | |
| GSE53624 | TNRC6C | 57690 | 52281 | 0.3379 | 0.0025 | |
| GSE63941 | TNRC6C | 57690 | 222820_at | -0.6406 | 0.3590 | |
| GSE77861 | TNRC6C | 57690 | 242314_at | -0.1182 | 0.4137 | |
| GSE97050 | TNRC6C | 57690 | A_33_P3302428 | -0.2854 | 0.3835 | |
| SRP007169 | TNRC6C | 57690 | RNAseq | 1.0770 | 0.0099 | |
| SRP008496 | TNRC6C | 57690 | RNAseq | 0.7200 | 0.0268 | |
| SRP064894 | TNRC6C | 57690 | RNAseq | 0.1033 | 0.5744 | |
| SRP133303 | TNRC6C | 57690 | RNAseq | -0.2437 | 0.2291 | |
| SRP159526 | TNRC6C | 57690 | RNAseq | 0.3577 | 0.4007 | |
| SRP193095 | TNRC6C | 57690 | RNAseq | 0.1768 | 0.2380 | |
| SRP219564 | TNRC6C | 57690 | RNAseq | 0.1320 | 0.7813 | |
| TCGA | TNRC6C | 57690 | RNAseq | -0.2667 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TNRC6C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNRC6C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNRC6C | 57690 | 5 | 4 | 21 | |
| GSE20123 | TNRC6C | 57690 | 5 | 4 | 21 | |
| GSE43470 | TNRC6C | 57690 | 3 | 4 | 36 | |
| GSE46452 | TNRC6C | 57690 | 33 | 0 | 26 | |
| GSE47630 | TNRC6C | 57690 | 8 | 1 | 31 | |
| GSE54993 | TNRC6C | 57690 | 2 | 5 | 63 | |
| GSE54994 | TNRC6C | 57690 | 10 | 4 | 39 | |
| GSE60625 | TNRC6C | 57690 | 6 | 0 | 5 | |
| GSE74703 | TNRC6C | 57690 | 3 | 2 | 31 | |
| GSE74704 | TNRC6C | 57690 | 4 | 3 | 13 | |
| TCGA | TNRC6C | 57690 | 31 | 8 | 57 |
Total number of gains: 110; Total number of losses: 35; Total Number of normals: 343.
Somatic mutations of TNRC6C:
Generating mutation plots.
Highly correlated genes for TNRC6C:
Showing top 20/409 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNRC6C | TSHZ1 | 0.755553 | 3 | 0 | 3 |
| TNRC6C | KCNT2 | 0.728229 | 3 | 0 | 3 |
| TNRC6C | MEOX2 | 0.72498 | 3 | 0 | 3 |
| TNRC6C | NFASC | 0.724074 | 3 | 0 | 3 |
| TNRC6C | TNS1 | 0.722525 | 3 | 0 | 3 |
| TNRC6C | PDE5A | 0.714983 | 3 | 0 | 3 |
| TNRC6C | FOXF1 | 0.714009 | 3 | 0 | 3 |
| TNRC6C | CLIP3 | 0.712323 | 3 | 0 | 3 |
| TNRC6C | EPS8 | 0.710677 | 3 | 0 | 3 |
| TNRC6C | TCF15 | 0.705396 | 3 | 0 | 3 |
| TNRC6C | ADARB1 | 0.704976 | 5 | 0 | 5 |
| TNRC6C | LIFR | 0.702836 | 3 | 0 | 3 |
| TNRC6C | DTNA | 0.702484 | 3 | 0 | 3 |
| TNRC6C | PGM5 | 0.70215 | 4 | 0 | 4 |
| TNRC6C | FBLN1 | 0.699878 | 3 | 0 | 3 |
| TNRC6C | ITGA9 | 0.697767 | 3 | 0 | 3 |
| TNRC6C | OLFM1 | 0.696927 | 4 | 0 | 3 |
| TNRC6C | LDB3 | 0.696509 | 3 | 0 | 3 |
| TNRC6C | CHADL | 0.69415 | 3 | 0 | 3 |
| TNRC6C | BMX | 0.694107 | 3 | 0 | 3 |
For details and further investigation, click here
