| Full name: golgi SNAP receptor complex member 1 | Alias Symbol: GOS28|P28|GS28|GOS-28|GOLIM2 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 9527 | HGNC ID: HGNC:4430 | Ensembl Gene: ENSG00000108587 | OMIM ID: 604026 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GOSR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GOSR1 | 9527 | 204630_s_at | 0.2602 | 0.2903 | |
| GSE20347 | GOSR1 | 9527 | 204630_s_at | 0.2798 | 0.0410 | |
| GSE23400 | GOSR1 | 9527 | 204630_s_at | 0.3251 | 0.0002 | |
| GSE26886 | GOSR1 | 9527 | 204630_s_at | 0.3626 | 0.0515 | |
| GSE29001 | GOSR1 | 9527 | 204630_s_at | 0.0882 | 0.7379 | |
| GSE38129 | GOSR1 | 9527 | 204630_s_at | 0.1805 | 0.1737 | |
| GSE45670 | GOSR1 | 9527 | 204630_s_at | 0.3288 | 0.0066 | |
| GSE53622 | GOSR1 | 9527 | 157749 | -0.4172 | 0.0000 | |
| GSE53624 | GOSR1 | 9527 | 157749 | -0.1968 | 0.0019 | |
| GSE63941 | GOSR1 | 9527 | 204630_s_at | 1.0496 | 0.0178 | |
| GSE77861 | GOSR1 | 9527 | 204630_s_at | 0.6616 | 0.0387 | |
| GSE97050 | GOSR1 | 9527 | A_33_P3279431 | -0.2121 | 0.3686 | |
| SRP007169 | GOSR1 | 9527 | RNAseq | 0.4053 | 0.1848 | |
| SRP008496 | GOSR1 | 9527 | RNAseq | 0.4334 | 0.0203 | |
| SRP064894 | GOSR1 | 9527 | RNAseq | 0.0858 | 0.3740 | |
| SRP133303 | GOSR1 | 9527 | RNAseq | 0.0238 | 0.8032 | |
| SRP159526 | GOSR1 | 9527 | RNAseq | 0.2146 | 0.2652 | |
| SRP193095 | GOSR1 | 9527 | RNAseq | 0.0702 | 0.3046 | |
| SRP219564 | GOSR1 | 9527 | RNAseq | 0.0910 | 0.7095 | |
| TCGA | GOSR1 | 9527 | RNAseq | -0.1215 | 0.0075 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GOSR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GOSR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GOSR1 | 9527 | 7 | 2 | 21 | |
| GSE20123 | GOSR1 | 9527 | 8 | 2 | 20 | |
| GSE43470 | GOSR1 | 9527 | 0 | 1 | 42 | |
| GSE46452 | GOSR1 | 9527 | 33 | 1 | 25 | |
| GSE47630 | GOSR1 | 9527 | 7 | 1 | 32 | |
| GSE54993 | GOSR1 | 9527 | 2 | 3 | 65 | |
| GSE54994 | GOSR1 | 9527 | 7 | 6 | 40 | |
| GSE60625 | GOSR1 | 9527 | 4 | 0 | 7 | |
| GSE74703 | GOSR1 | 9527 | 0 | 1 | 35 | |
| GSE74704 | GOSR1 | 9527 | 5 | 2 | 13 | |
| TCGA | GOSR1 | 9527 | 19 | 11 | 66 |
Total number of gains: 92; Total number of losses: 30; Total Number of normals: 366.
Somatic mutations of GOSR1:
Generating mutation plots.
Highly correlated genes for GOSR1:
Showing top 20/699 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GOSR1 | MSI2 | 0.836326 | 3 | 0 | 3 |
| GOSR1 | POGK | 0.811969 | 3 | 0 | 3 |
| GOSR1 | ZNF280C | 0.798039 | 4 | 0 | 4 |
| GOSR1 | MIER2 | 0.785059 | 3 | 0 | 3 |
| GOSR1 | FXR2 | 0.774122 | 4 | 0 | 4 |
| GOSR1 | BPTF | 0.770661 | 3 | 0 | 3 |
| GOSR1 | IRF2BP2 | 0.770362 | 3 | 0 | 3 |
| GOSR1 | SLC39A3 | 0.767277 | 3 | 0 | 3 |
| GOSR1 | IWS1 | 0.765336 | 4 | 0 | 4 |
| GOSR1 | ZNF397 | 0.759687 | 3 | 0 | 3 |
| GOSR1 | CYHR1 | 0.758197 | 3 | 0 | 3 |
| GOSR1 | CNOT10 | 0.744209 | 3 | 0 | 3 |
| GOSR1 | AP3B2 | 0.741013 | 3 | 0 | 3 |
| GOSR1 | ZNF787 | 0.737831 | 4 | 0 | 3 |
| GOSR1 | SIPA1L2 | 0.737673 | 4 | 0 | 4 |
| GOSR1 | ZNF830 | 0.734746 | 4 | 0 | 4 |
| GOSR1 | CEP95 | 0.729878 | 4 | 0 | 4 |
| GOSR1 | EXOSC8 | 0.727814 | 3 | 0 | 3 |
| GOSR1 | PDRG1 | 0.72468 | 3 | 0 | 3 |
| GOSR1 | TKT | 0.722504 | 3 | 0 | 3 |
For details and further investigation, click here
