GLDN

 

Full name: gliomedin Alias Symbol: CRG-L2|CLOM|colmedin|UNC-112
Type: protein-coding gene Cytoband: 15q21.2
Entrez ID: 342035 HGNC ID: HGNC:29514 Ensembl Gene: ENSG00000186417 OMIM ID: 608603
Drug and gene relationship at DGIdb

 

Expression of GLDN:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GLDN 342035 230360_at 0.6462 0.4094
GSE26886 GLDN 342035 232649_at 0.2879 0.0215
GSE45670 GLDN 342035 232649_at 0.0526 0.5803
GSE53622 GLDN 342035 87555 -0.4182 0.0109
GSE53624 GLDN 342035 87555 0.2499 0.0838
GSE63941 GLDN 342035 232649_at -0.2501 0.1783
GSE77861 GLDN 342035 232649_at -0.0729 0.4607
GSE97050 GLDN 342035 A_24_P49199 -0.2248 0.6479
SRP007169 GLDN 342035 RNAseq 0.8680 0.2693
SRP064894 GLDN 342035 RNAseq 1.3668 0.0012
SRP133303 GLDN 342035 RNAseq 0.8752 0.0307
SRP159526 GLDN 342035 RNAseq -0.7139 0.1138
SRP193095 GLDN 342035 RNAseq 0.5005 0.0549
SRP219564 GLDN 342035 RNAseq 0.7272 0.2131
TCGA GLDN 342035 RNAseq -0.2287 0.2466

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by GLDN expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GLDN:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GLDN 342035 5 3 22
GSE20123 GLDN 342035 5 3 22
GSE43470 GLDN 342035 5 3 35
GSE46452 GLDN 342035 3 7 49
GSE47630 GLDN 342035 8 10 22
GSE54993 GLDN 342035 4 6 60
GSE54994 GLDN 342035 5 7 41
GSE60625 GLDN 342035 4 0 7
GSE74703 GLDN 342035 5 2 29
GSE74704 GLDN 342035 2 3 15
TCGA GLDN 342035 9 18 69

Total number of gains: 55; Total number of losses: 62; Total Number of normals: 371.  


 

Somatic mutations of GLDN:

 

Generating mutation plots.

 

Highly correlated genes for GLDN:

 

Showing top 20/46 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GLDNGAS6-AS10.690144303
GLDNFRS30.682726303
GLDNCDK200.678337303
GLDNTCF150.666529303
GLDNLINC008800.645319303
GLDNCACNA1H0.634857303
GLDNABHD16B0.627392303
GLDNATF50.627238303
GLDNHTRA30.621068303
GLDNCTXN10.61735303
GLDNOGG10.615243303
GLDNC9orf500.612168303
GLDNCOL19A10.608826503
GLDNIP6K10.607645303
GLDNPTP4A30.605904403
GLDNC2CD4B0.588775303
GLDNCLCF10.585608303
GLDNRAB3A0.58452303
GLDNLENG10.584468303
GLDNTFEB0.584014403

For details and further investigation, click here