| Full name: TATA-box binding protein like 1 | Alias Symbol: TLP|STUD|TRF2|TLF | ||
| Type: protein-coding gene | Cytoband: 6q23.2 | ||
| Entrez ID: 9519 | HGNC ID: HGNC:11589 | Ensembl Gene: ENSG00000028839 | OMIM ID: 605521 |
| Drug and gene relationship at DGIdb | |||
TBPL1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05166 | HTLV-I infection |
Expression of TBPL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBPL1 | 9519 | 208398_s_at | 0.5314 | 0.1698 | |
| GSE20347 | TBPL1 | 9519 | 208398_s_at | 0.7486 | 0.0077 | |
| GSE23400 | TBPL1 | 9519 | 208398_s_at | 0.6221 | 0.0000 | |
| GSE26886 | TBPL1 | 9519 | 208398_s_at | 0.8996 | 0.0000 | |
| GSE29001 | TBPL1 | 9519 | 208398_s_at | 0.6622 | 0.0715 | |
| GSE38129 | TBPL1 | 9519 | 208398_s_at | 0.7481 | 0.0000 | |
| GSE45670 | TBPL1 | 9519 | 208398_s_at | 0.5535 | 0.0002 | |
| GSE53622 | TBPL1 | 9519 | 155336 | 0.4563 | 0.0000 | |
| GSE53624 | TBPL1 | 9519 | 109110 | 0.7430 | 0.0000 | |
| GSE63941 | TBPL1 | 9519 | 208398_s_at | 0.3260 | 0.4394 | |
| GSE77861 | TBPL1 | 9519 | 208398_s_at | 0.7402 | 0.0104 | |
| GSE97050 | TBPL1 | 9519 | A_33_P3380682 | 0.4677 | 0.1782 | |
| SRP007169 | TBPL1 | 9519 | RNAseq | 0.7011 | 0.0994 | |
| SRP008496 | TBPL1 | 9519 | RNAseq | 0.8313 | 0.0026 | |
| SRP064894 | TBPL1 | 9519 | RNAseq | 0.5038 | 0.0002 | |
| SRP133303 | TBPL1 | 9519 | RNAseq | 0.9451 | 0.0000 | |
| SRP159526 | TBPL1 | 9519 | RNAseq | 0.5179 | 0.0221 | |
| SRP193095 | TBPL1 | 9519 | RNAseq | 0.1833 | 0.0978 | |
| SRP219564 | TBPL1 | 9519 | RNAseq | 0.1430 | 0.6799 | |
| TCGA | TBPL1 | 9519 | RNAseq | 0.1067 | 0.0899 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBPL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBPL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBPL1 | 9519 | 3 | 4 | 23 | |
| GSE20123 | TBPL1 | 9519 | 4 | 3 | 23 | |
| GSE43470 | TBPL1 | 9519 | 5 | 0 | 38 | |
| GSE46452 | TBPL1 | 9519 | 3 | 10 | 46 | |
| GSE47630 | TBPL1 | 9519 | 10 | 4 | 26 | |
| GSE54993 | TBPL1 | 9519 | 3 | 2 | 65 | |
| GSE54994 | TBPL1 | 9519 | 9 | 7 | 37 | |
| GSE60625 | TBPL1 | 9519 | 0 | 1 | 10 | |
| GSE74703 | TBPL1 | 9519 | 4 | 0 | 32 | |
| GSE74704 | TBPL1 | 9519 | 1 | 1 | 18 | |
| TCGA | TBPL1 | 9519 | 12 | 18 | 66 |
Total number of gains: 54; Total number of losses: 50; Total Number of normals: 384.
Somatic mutations of TBPL1:
Generating mutation plots.
Highly correlated genes for TBPL1:
Showing top 20/1786 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBPL1 | INPP5B | 0.787119 | 3 | 0 | 3 |
| TBPL1 | RFX7 | 0.777706 | 3 | 0 | 3 |
| TBPL1 | LRRC58 | 0.762756 | 5 | 0 | 5 |
| TBPL1 | LRRCC1 | 0.761398 | 3 | 0 | 3 |
| TBPL1 | TMTC1 | 0.756971 | 3 | 0 | 3 |
| TBPL1 | SCNM1 | 0.755229 | 3 | 0 | 3 |
| TBPL1 | WTAP | 0.749808 | 6 | 0 | 6 |
| TBPL1 | ZNF680 | 0.747943 | 3 | 0 | 3 |
| TBPL1 | DTNBP1 | 0.747711 | 3 | 0 | 3 |
| TBPL1 | SUN1 | 0.740287 | 3 | 0 | 3 |
| TBPL1 | SLC39A3 | 0.73915 | 4 | 0 | 4 |
| TBPL1 | C12orf57 | 0.734209 | 4 | 0 | 4 |
| TBPL1 | TMEM201 | 0.729759 | 4 | 0 | 4 |
| TBPL1 | PNKP | 0.72817 | 3 | 0 | 3 |
| TBPL1 | PYCR2 | 0.726305 | 3 | 0 | 3 |
| TBPL1 | TMSB15B | 0.725653 | 3 | 0 | 3 |
| TBPL1 | SIX4 | 0.724723 | 7 | 0 | 7 |
| TBPL1 | SF1 | 0.722761 | 4 | 0 | 4 |
| TBPL1 | RBMX | 0.721751 | 3 | 0 | 3 |
| TBPL1 | ZNF317 | 0.719931 | 6 | 0 | 5 |
For details and further investigation, click here
