Full name: ACD shelterin complex subunit and telomerase recruitment factor	Alias Symbol: Ptop|Pip1|Tpp1|Tint1
Type: protein-coding gene	Cytoband: 16q22.1
Entrez ID: 65057	HGNC ID: HGNC:25070	Ensembl Gene: ENSG00000102977	OMIM ID: 609377
Drug and gene relationship at DGIdb

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Expression of ACD:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	ACD	65057	204617_s_at	0.5782	0.2426	Show
GSE20347	ACD	65057	204617_s_at	1.0455	0.0000	Show
GSE23400	ACD	65057	204617_s_at	0.4391	0.0000	Show
GSE26886	ACD	65057	204617_s_at	1.2947	0.0000	Show
GSE29001	ACD	65057	204617_s_at	0.5134	0.0011	Show
GSE38129	ACD	65057	204617_s_at	0.8905	0.0000	Show
GSE45670	ACD	65057	204617_s_at	0.3559	0.0848	Show
GSE53622	ACD	65057	38898	0.6292	0.0000	Show
GSE53624	ACD	65057	38898	1.0013	0.0000	Show
GSE63941	ACD	65057	204617_s_at	1.3068	0.0149	Show
GSE77861	ACD	65057	204617_s_at	0.5911	0.0151	Show
GSE97050	ACD	65057	A_33_P3359071	0.3310	0.3415	Show
SRP007169	ACD	65057	RNAseq	1.1277	0.0104	Show
SRP008496	ACD	65057	RNAseq	0.8292	0.0533	Show
SRP064894	ACD	65057	RNAseq	0.8650	0.0010	Show
SRP133303	ACD	65057	RNAseq	0.5237	0.0050	Show
SRP159526	ACD	65057	RNAseq	1.2711	0.0106	Show
SRP193095	ACD	65057	RNAseq	1.0131	0.0000	Show
SRP219564	ACD	65057	RNAseq	0.4689	0.1243	Show
TCGA	ACD	65057	RNAseq	0.2778	0.0000	Show

Upregulated datasets: 7; Downregulated datasets: 0.  Download Data

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Survival by ACD expression:

 

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Copy number change of ACD:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	ACD	65057	9	2	19	Show
GSE20123	ACD	65057	9	2	19	Show
GSE43470	ACD	65057	1	9	33	Show
GSE46452	ACD	65057	38	1	20	Show
GSE47630	ACD	65057	11	8	21	Show
GSE54993	ACD	65057	2	4	64	Show
GSE54994	ACD	65057	8	10	35	Show
GSE60625	ACD	65057	4	0	7	Show
GSE74703	ACD	65057	1	6	29	Show
GSE74704	ACD	65057	5	1	14	Show
TCGA	ACD	65057	29	12	55	Show

Total number of gains: 117; Total number of losses: 55; Total Number of normals: 316.  Download Data

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Somatic mutations of ACD:

 

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Highly correlated genes for ACD:

 

Showing top 20/1903 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
ACD	FADS1	0.779526	3	0	3
ACD	FHL3	0.768015	4	0	4
ACD	TCP1	0.762262	3	0	3
ACD	RAB34	0.762003	3	0	3
ACD	RPS19BP1	0.754165	3	0	3
ACD	PYCR2	0.744265	3	0	3
ACD	IRF2BP2	0.74376	3	0	3
ACD	CRTC2	0.74371	4	0	4
ACD	SCNM1	0.737496	3	0	3
ACD	RGS1	0.735481	3	0	3
ACD	PRPS1	0.733851	11	0	10
ACD	COPRS	0.732819	6	0	6
ACD	ZNF417	0.732468	3	0	3
ACD	SSBP4	0.729512	4	0	4
ACD	PFDN2	0.728362	10	0	10
ACD	MMD	0.728163	11	0	11
ACD	USB1	0.726576	10	0	10
ACD	MRGBP	0.726443	10	0	10
ACD	FBXO16	0.720874	3	0	3
ACD	LPCAT1	0.718965	11	0	11

For details and further investigation, click here