POLR3F

 

Full name: RNA polymerase III subunit F Alias Symbol: RPC39|RPC6
Type: protein-coding gene Cytoband: 20p11.23
Entrez ID: 10621 HGNC ID: HGNC:15763 Ensembl Gene: ENSG00000132664 OMIM ID: 617455
Drug and gene relationship at DGIdb

 

Expression of POLR3F:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 POLR3F 10621 205218_at 0.4961 0.2643
GSE20347 POLR3F 10621 205218_at 0.2713 0.0955
GSE23400 POLR3F 10621 205218_at 0.0735 0.0014
GSE26886 POLR3F 10621 205218_at -0.0505 0.8888
GSE29001 POLR3F 10621 205218_at 0.2525 0.4543
GSE38129 POLR3F 10621 205218_at 0.3785 0.0014
GSE45670 POLR3F 10621 205218_at 0.2152 0.2715
GSE53622 POLR3F 10621 134743 0.4529 0.0000
GSE53624 POLR3F 10621 134743 0.5426 0.0000
GSE63941 POLR3F 10621 205218_at -0.6634 0.1187
GSE77861 POLR3F 10621 205218_at 0.4264 0.0343
GSE97050 POLR3F 10621 A_23_P166122 0.2399 0.3791
SRP007169 POLR3F 10621 RNAseq 0.2417 0.5858
SRP008496 POLR3F 10621 RNAseq 0.3148 0.2823
SRP064894 POLR3F 10621 RNAseq 0.4281 0.0061
SRP133303 POLR3F 10621 RNAseq 0.4517 0.0001
SRP159526 POLR3F 10621 RNAseq 0.2360 0.2758
SRP193095 POLR3F 10621 RNAseq 0.2096 0.0569
SRP219564 POLR3F 10621 RNAseq -0.1003 0.6855
TCGA POLR3F 10621 RNAseq 0.0852 0.1774

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by POLR3F expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of POLR3F:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 POLR3F 10621 12 2 16
GSE20123 POLR3F 10621 12 2 16
GSE43470 POLR3F 10621 11 1 31
GSE46452 POLR3F 10621 27 1 31
GSE47630 POLR3F 10621 17 4 19
GSE54993 POLR3F 10621 0 15 55
GSE54994 POLR3F 10621 26 2 25
GSE60625 POLR3F 10621 0 0 11
GSE74703 POLR3F 10621 8 1 27
GSE74704 POLR3F 10621 7 2 11
TCGA POLR3F 10621 44 10 42

Total number of gains: 164; Total number of losses: 40; Total Number of normals: 284.  

 

Somatic mutations of POLR3F:

 

Generating mutation plots.

 

Highly correlated genes for POLR3F:

 

Showing top 20/993 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
POLR3FC18orf540.766109505
POLR3FNCOA30.751276303
POLR3FKLHL150.748996303
POLR3FRIOK20.744222303
POLR3FKLHL80.738921303
POLR3FALG10.738747303
POLR3FMMS22L0.735568303
POLR3FBOLA30.724691404
POLR3FTRUB10.724343404
POLR3FZNF3970.723651303
POLR3FSLC35A50.720242404
POLR3FKIF18A0.719654807
POLR3FPEX130.719145303
POLR3FGMCL10.714394303
POLR3FL3MBTL30.714135303
POLR3FHAUS10.713777403
POLR3FNF10.712984303
POLR3FNXT10.71133210010
POLR3FXRN20.710746605
POLR3FPDRG10.708934606

For details and further investigation, click here