| Full name: nucleoporin 107 | Alias Symbol: NUP84 | ||
| Type: protein-coding gene | Cytoband: 12q15 | ||
| Entrez ID: 57122 | HGNC ID: HGNC:29914 | Ensembl Gene: ENSG00000111581 | OMIM ID: 607617 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUP107:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUP107 | 57122 | 218768_at | 0.7017 | 0.0370 | |
| GSE20347 | NUP107 | 57122 | 218768_at | 1.2368 | 0.0000 | |
| GSE23400 | NUP107 | 57122 | 218768_at | 1.2206 | 0.0000 | |
| GSE26886 | NUP107 | 57122 | 218768_at | 0.5072 | 0.0538 | |
| GSE29001 | NUP107 | 57122 | 218768_at | 1.2152 | 0.0001 | |
| GSE38129 | NUP107 | 57122 | 218768_at | 1.3246 | 0.0000 | |
| GSE45670 | NUP107 | 57122 | 218768_at | 0.5859 | 0.0006 | |
| GSE53622 | NUP107 | 57122 | 78159 | 0.6755 | 0.0000 | |
| GSE53624 | NUP107 | 57122 | 78159 | 1.0080 | 0.0000 | |
| GSE63941 | NUP107 | 57122 | 218768_at | 1.3606 | 0.0439 | |
| GSE77861 | NUP107 | 57122 | 218768_at | 1.0969 | 0.0016 | |
| GSE97050 | NUP107 | 57122 | A_23_P14062 | 0.3758 | 0.2219 | |
| SRP007169 | NUP107 | 57122 | RNAseq | 1.3787 | 0.0007 | |
| SRP008496 | NUP107 | 57122 | RNAseq | 1.3093 | 0.0000 | |
| SRP064894 | NUP107 | 57122 | RNAseq | 0.8827 | 0.0003 | |
| SRP133303 | NUP107 | 57122 | RNAseq | 1.4490 | 0.0000 | |
| SRP159526 | NUP107 | 57122 | RNAseq | 1.2303 | 0.0010 | |
| SRP193095 | NUP107 | 57122 | RNAseq | 0.6928 | 0.0000 | |
| TCGA | NUP107 | 57122 | RNAseq | 0.3918 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by NUP107 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUP107:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUP107 | 57122 | 6 | 1 | 23 | |
| GSE20123 | NUP107 | 57122 | 6 | 0 | 24 | |
| GSE43470 | NUP107 | 57122 | 5 | 0 | 38 | |
| GSE46452 | NUP107 | 57122 | 12 | 0 | 47 | |
| GSE47630 | NUP107 | 57122 | 10 | 1 | 29 | |
| GSE54993 | NUP107 | 57122 | 0 | 8 | 62 | |
| GSE54994 | NUP107 | 57122 | 7 | 1 | 45 | |
| GSE60625 | NUP107 | 57122 | 0 | 0 | 11 | |
| GSE74703 | NUP107 | 57122 | 5 | 0 | 31 | |
| GSE74704 | NUP107 | 57122 | 5 | 0 | 15 | |
| TCGA | NUP107 | 57122 | 23 | 8 | 65 |
Total number of gains: 79; Total number of losses: 19; Total Number of normals: 390.
Somatic mutations of NUP107:
Generating mutation plots.
Highly correlated genes for NUP107:
Showing top 20/2021 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUP107 | NEDD1 | 0.810287 | 7 | 0 | 7 |
| NUP107 | UBR1 | 0.794373 | 3 | 0 | 3 |
| NUP107 | ISY1 | 0.786578 | 3 | 0 | 3 |
| NUP107 | CCT2 | 0.783638 | 13 | 0 | 13 |
| NUP107 | C12orf57 | 0.773929 | 3 | 0 | 3 |
| NUP107 | GINS1 | 0.764576 | 12 | 0 | 12 |
| NUP107 | NCAPG2 | 0.763372 | 11 | 0 | 10 |
| NUP107 | TTL | 0.759792 | 7 | 0 | 7 |
| NUP107 | DTX4 | 0.751905 | 3 | 0 | 3 |
| NUP107 | RACGAP1 | 0.750541 | 11 | 0 | 10 |
| NUP107 | SNX13 | 0.749831 | 3 | 0 | 3 |
| NUP107 | TCF3 | 0.749324 | 11 | 0 | 11 |
| NUP107 | KIF23 | 0.748785 | 12 | 0 | 12 |
| NUP107 | KIF14 | 0.747094 | 12 | 0 | 12 |
| NUP107 | BLM | 0.746859 | 12 | 0 | 12 |
| NUP107 | MCM6 | 0.743518 | 13 | 0 | 11 |
| NUP107 | SNRPG | 0.743132 | 12 | 0 | 10 |
| NUP107 | ECT2 | 0.742102 | 12 | 0 | 12 |
| NUP107 | DNAJC2 | 0.741628 | 12 | 0 | 11 |
| NUP107 | CPSF6 | 0.740542 | 13 | 0 | 12 |
For details and further investigation, click here
