| Full name: testis associated actin remodelling kinase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p34.1 | ||
| Entrez ID: 10420 | HGNC ID: HGNC:11732 | Ensembl Gene: ENSG00000070759 | OMIM ID: 604746 |
| Drug and gene relationship at DGIdb | |||
Expression of TESK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TESK2 | 10420 | 205486_at | -0.2075 | 0.6493 | |
| GSE20347 | TESK2 | 10420 | 205486_at | -0.1789 | 0.1406 | |
| GSE23400 | TESK2 | 10420 | 205486_at | -0.0734 | 0.0503 | |
| GSE26886 | TESK2 | 10420 | 205486_at | -0.7983 | 0.0003 | |
| GSE29001 | TESK2 | 10420 | 205486_at | -0.4082 | 0.0300 | |
| GSE38129 | TESK2 | 10420 | 205486_at | -0.1489 | 0.1536 | |
| GSE45670 | TESK2 | 10420 | 205486_at | -0.3182 | 0.0227 | |
| GSE53622 | TESK2 | 10420 | 92235 | -0.6525 | 0.0002 | |
| GSE53624 | TESK2 | 10420 | 92235 | -0.5906 | 0.0000 | |
| GSE63941 | TESK2 | 10420 | 205486_at | 0.2701 | 0.6200 | |
| GSE77861 | TESK2 | 10420 | 205486_at | -0.0612 | 0.8733 | |
| SRP007169 | TESK2 | 10420 | RNAseq | -1.4797 | 0.0000 | |
| SRP008496 | TESK2 | 10420 | RNAseq | -1.6461 | 0.0000 | |
| SRP064894 | TESK2 | 10420 | RNAseq | -0.6643 | 0.0005 | |
| SRP133303 | TESK2 | 10420 | RNAseq | -0.8639 | 0.0000 | |
| SRP159526 | TESK2 | 10420 | RNAseq | -0.8976 | 0.0159 | |
| SRP193095 | TESK2 | 10420 | RNAseq | -0.6303 | 0.0000 | |
| SRP219564 | TESK2 | 10420 | RNAseq | -0.5644 | 0.1974 | |
| TCGA | TESK2 | 10420 | RNAseq | 0.0057 | 0.9505 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TESK2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TESK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TESK2 | 10420 | 4 | 3 | 23 | |
| GSE20123 | TESK2 | 10420 | 4 | 2 | 24 | |
| GSE43470 | TESK2 | 10420 | 7 | 2 | 34 | |
| GSE46452 | TESK2 | 10420 | 2 | 1 | 56 | |
| GSE47630 | TESK2 | 10420 | 9 | 3 | 28 | |
| GSE54993 | TESK2 | 10420 | 0 | 1 | 69 | |
| GSE54994 | TESK2 | 10420 | 13 | 2 | 38 | |
| GSE60625 | TESK2 | 10420 | 0 | 0 | 11 | |
| GSE74703 | TESK2 | 10420 | 6 | 1 | 29 | |
| GSE74704 | TESK2 | 10420 | 2 | 0 | 18 | |
| TCGA | TESK2 | 10420 | 11 | 16 | 69 |
Total number of gains: 58; Total number of losses: 31; Total Number of normals: 399.
Somatic mutations of TESK2:
Generating mutation plots.
Highly correlated genes for TESK2:
Showing top 20/358 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TESK2 | DCAF10 | 0.771103 | 3 | 0 | 3 |
| TESK2 | BTBD7 | 0.726371 | 3 | 0 | 3 |
| TESK2 | SLC18B1 | 0.678495 | 4 | 0 | 4 |
| TESK2 | SPRYD4 | 0.675751 | 3 | 0 | 3 |
| TESK2 | YIPF1 | 0.673797 | 4 | 0 | 4 |
| TESK2 | CAMSAP3 | 0.661102 | 3 | 0 | 3 |
| TESK2 | TMEM144 | 0.655408 | 6 | 0 | 5 |
| TESK2 | TIFA | 0.644542 | 5 | 0 | 5 |
| TESK2 | ALG14 | 0.641865 | 3 | 0 | 3 |
| TESK2 | SYTL1 | 0.625388 | 5 | 0 | 4 |
| TESK2 | RASSF5 | 0.623857 | 5 | 0 | 3 |
| TESK2 | PLEKHA7 | 0.623454 | 5 | 0 | 4 |
| TESK2 | WDR26 | 0.616808 | 4 | 0 | 3 |
| TESK2 | GOLGA4 | 0.616295 | 4 | 0 | 3 |
| TESK2 | CXCL17 | 0.616128 | 5 | 0 | 4 |
| TESK2 | MIR34A | 0.61251 | 3 | 0 | 3 |
| TESK2 | SAMD10 | 0.610905 | 3 | 0 | 3 |
| TESK2 | TINCR | 0.609261 | 6 | 0 | 5 |
| TESK2 | ATG2B | 0.60909 | 3 | 0 | 3 |
| TESK2 | ARPC3 | 0.60644 | 5 | 0 | 4 |
For details and further investigation, click here
