| Full name: TRAF interacting protein with forkhead associated domain | Alias Symbol: MGC20791|T2BP|T6BP|TIFAA | ||
| Type: protein-coding gene | Cytoband: 4q25 | ||
| Entrez ID: 92610 | HGNC ID: HGNC:19075 | Ensembl Gene: ENSG00000145365 | OMIM ID: 609028 |
| Drug and gene relationship at DGIdb | |||
Expression of TIFA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TIFA | 92610 | 226117_at | -0.3556 | 0.5107 | |
| GSE26886 | TIFA | 92610 | 226117_at | -1.8471 | 0.0000 | |
| GSE45670 | TIFA | 92610 | 226117_at | -0.8908 | 0.0056 | |
| GSE53622 | TIFA | 92610 | 20779 | -0.9105 | 0.0000 | |
| GSE53624 | TIFA | 92610 | 20779 | -0.9889 | 0.0000 | |
| GSE63941 | TIFA | 92610 | 226117_at | 0.7959 | 0.0986 | |
| GSE77861 | TIFA | 92610 | 226117_at | -1.8519 | 0.0003 | |
| GSE97050 | TIFA | 92610 | A_23_P352619 | -0.5930 | 0.1860 | |
| SRP007169 | TIFA | 92610 | RNAseq | -2.0201 | 0.0000 | |
| SRP008496 | TIFA | 92610 | RNAseq | -1.9727 | 0.0000 | |
| SRP064894 | TIFA | 92610 | RNAseq | -1.0095 | 0.0000 | |
| SRP133303 | TIFA | 92610 | RNAseq | -0.7583 | 0.0017 | |
| SRP159526 | TIFA | 92610 | RNAseq | -0.7819 | 0.0588 | |
| SRP193095 | TIFA | 92610 | RNAseq | -1.2700 | 0.0000 | |
| SRP219564 | TIFA | 92610 | RNAseq | -1.0003 | 0.0103 | |
| TCGA | TIFA | 92610 | RNAseq | -0.0976 | 0.1920 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by TIFA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TIFA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TIFA | 92610 | 1 | 13 | 16 | |
| GSE20123 | TIFA | 92610 | 1 | 13 | 16 | |
| GSE43470 | TIFA | 92610 | 0 | 14 | 29 | |
| GSE46452 | TIFA | 92610 | 1 | 36 | 22 | |
| GSE47630 | TIFA | 92610 | 0 | 20 | 20 | |
| GSE54993 | TIFA | 92610 | 9 | 0 | 61 | |
| GSE54994 | TIFA | 92610 | 1 | 10 | 42 | |
| GSE60625 | TIFA | 92610 | 0 | 3 | 8 | |
| GSE74703 | TIFA | 92610 | 0 | 12 | 24 | |
| GSE74704 | TIFA | 92610 | 0 | 7 | 13 | |
| TCGA | TIFA | 92610 | 8 | 35 | 53 |
Total number of gains: 21; Total number of losses: 163; Total Number of normals: 304.
Somatic mutations of TIFA:
Generating mutation plots.
Highly correlated genes for TIFA:
Showing top 20/1419 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TIFA | MKRN2 | 0.819676 | 4 | 0 | 4 |
| TIFA | BBIP1 | 0.808435 | 4 | 0 | 4 |
| TIFA | RPL14 | 0.806882 | 3 | 0 | 3 |
| TIFA | TPRG1 | 0.800606 | 6 | 0 | 6 |
| TIFA | SFTA2 | 0.794031 | 4 | 0 | 4 |
| TIFA | PLEKHA7 | 0.791327 | 8 | 0 | 8 |
| TIFA | TJP3 | 0.787436 | 6 | 0 | 6 |
| TIFA | NAGK | 0.78254 | 7 | 0 | 7 |
| TIFA | CCNG2 | 0.779788 | 7 | 0 | 7 |
| TIFA | SCP2 | 0.779401 | 7 | 0 | 7 |
| TIFA | MSL3 | 0.77376 | 3 | 0 | 3 |
| TIFA | PADI1 | 0.771287 | 4 | 0 | 4 |
| TIFA | FCER1A | 0.760991 | 6 | 0 | 6 |
| TIFA | USP6NL | 0.758845 | 7 | 0 | 6 |
| TIFA | KLB | 0.758505 | 6 | 0 | 6 |
| TIFA | ANXA9 | 0.758316 | 7 | 0 | 7 |
| TIFA | LEPROT | 0.756744 | 3 | 0 | 3 |
| TIFA | ACAA1 | 0.755961 | 5 | 0 | 5 |
| TIFA | ACOX3 | 0.755961 | 7 | 0 | 7 |
| TIFA | SPNS2 | 0.755944 | 5 | 0 | 5 |
For details and further investigation, click here
