| Full name: microRNA 34a | Alias Symbol: hsa-mir-34a | ||
| Type: non-coding RNA | Cytoband: 1p36.22 | ||
| Entrez ID: 407040 | HGNC ID: HGNC:31635 | Ensembl Gene: ENSG00000284357 | OMIM ID: 611172 |
| Drug and gene relationship at DGIdb | |||
Expression of MIR34A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MIR34A | 407040 | 235571_at | -0.2451 | 0.3529 | |
| GSE26886 | MIR34A | 407040 | 235571_at | -0.3535 | 0.0949 | |
| GSE45670 | MIR34A | 407040 | 235571_at | -0.0256 | 0.9018 | |
| GSE63941 | MIR34A | 407040 | 235571_at | -1.6868 | 0.0005 | |
| GSE77861 | MIR34A | 407040 | 235571_at | -0.0600 | 0.6703 |
Upregulated datasets: 0; Downregulated datasets: 1.
Copy number change of MIR34A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MIR34A | 407040 | 1 | 5 | 24 | |
| GSE20123 | MIR34A | 407040 | 1 | 3 | 26 | |
| GSE43470 | MIR34A | 407040 | 6 | 5 | 32 | |
| GSE46452 | MIR34A | 407040 | 7 | 1 | 51 | |
| GSE47630 | MIR34A | 407040 | 8 | 4 | 28 | |
| GSE54993 | MIR34A | 407040 | 3 | 2 | 65 | |
| GSE54994 | MIR34A | 407040 | 12 | 4 | 37 | |
| GSE60625 | MIR34A | 407040 | 0 | 0 | 11 | |
| GSE74703 | MIR34A | 407040 | 5 | 3 | 28 | |
| GSE74704 | MIR34A | 407040 | 1 | 0 | 19 | |
| TCGA | MIR34A | 407040 | 11 | 24 | 61 |
Total number of gains: 55; Total number of losses: 51; Total Number of normals: 382.
Somatic mutations of MIR34A:
Generating mutation plots.
Highly correlated genes for MIR34A:
Showing top 20/47 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MIR34A | BCKDHA | 0.681412 | 3 | 0 | 3 |
| MIR34A | MON2 | 0.678186 | 3 | 0 | 3 |
| MIR34A | BNIP3L | 0.669697 | 3 | 0 | 3 |
| MIR34A | NUCB2 | 0.660083 | 3 | 0 | 3 |
| MIR34A | MIR210HG | 0.652995 | 3 | 0 | 3 |
| MIR34A | MTPN | 0.648795 | 3 | 0 | 3 |
| MIR34A | FANK1 | 0.646123 | 3 | 0 | 3 |
| MIR34A | SS18 | 0.644965 | 3 | 0 | 3 |
| MIR34A | UBAC2 | 0.64458 | 3 | 0 | 3 |
| MIR34A | NDST2 | 0.642839 | 3 | 0 | 3 |
| MIR34A | DHDDS | 0.640849 | 4 | 0 | 4 |
| MIR34A | VAT1 | 0.625476 | 3 | 0 | 3 |
| MIR34A | KSR1 | 0.622473 | 4 | 0 | 4 |
| MIR34A | SLC11A2 | 0.620555 | 3 | 0 | 3 |
| MIR34A | SRPX2 | 0.619081 | 3 | 0 | 3 |
| MIR34A | TESK2 | 0.61251 | 3 | 0 | 3 |
| MIR34A | GPRC5A | 0.600617 | 3 | 0 | 3 |
| MIR34A | NPAS2 | 0.598912 | 3 | 0 | 3 |
| MIR34A | B3GNT6 | 0.598495 | 4 | 0 | 3 |
| MIR34A | MGAT1 | 0.596322 | 3 | 0 | 3 |
For details and further investigation, click here
