| Full name: C-X-C motif chemokine ligand 17 | Alias Symbol: Dcip1|UNQ473|DMC|VCC1 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 284340 | HGNC ID: HGNC:19232 | Ensembl Gene: ENSG00000189377 | OMIM ID: 611387 |
| Drug and gene relationship at DGIdb | |||
Expression of CXCL17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CXCL17 | 284340 | 226960_at | -1.1302 | 0.3292 | |
| GSE26886 | CXCL17 | 284340 | 226960_at | -3.6225 | 0.0000 | |
| GSE45670 | CXCL17 | 284340 | 226960_at | -0.6994 | 0.2289 | |
| GSE53622 | CXCL17 | 284340 | 15563 | -2.8032 | 0.0000 | |
| GSE53624 | CXCL17 | 284340 | 15563 | -3.1324 | 0.0000 | |
| GSE63941 | CXCL17 | 284340 | 226960_at | 0.9038 | 0.4040 | |
| GSE77861 | CXCL17 | 284340 | 226960_at | -2.8012 | 0.0047 | |
| GSE97050 | CXCL17 | 284340 | A_23_P50269 | -0.4862 | 0.2850 | |
| SRP007169 | CXCL17 | 284340 | RNAseq | -4.4684 | 0.0000 | |
| SRP008496 | CXCL17 | 284340 | RNAseq | -4.8541 | 0.0000 | |
| SRP064894 | CXCL17 | 284340 | RNAseq | -3.3925 | 0.0000 | |
| SRP133303 | CXCL17 | 284340 | RNAseq | -2.6999 | 0.0000 | |
| SRP159526 | CXCL17 | 284340 | RNAseq | -3.8826 | 0.0000 | |
| SRP193095 | CXCL17 | 284340 | RNAseq | -2.3679 | 0.0000 | |
| SRP219564 | CXCL17 | 284340 | RNAseq | -2.0088 | 0.1339 | |
| TCGA | CXCL17 | 284340 | RNAseq | -1.1481 | 0.0045 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by CXCL17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CXCL17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CXCL17 | 284340 | 5 | 5 | 20 | |
| GSE20123 | CXCL17 | 284340 | 4 | 4 | 22 | |
| GSE43470 | CXCL17 | 284340 | 5 | 11 | 27 | |
| GSE46452 | CXCL17 | 284340 | 47 | 1 | 11 | |
| GSE47630 | CXCL17 | 284340 | 8 | 6 | 26 | |
| GSE54993 | CXCL17 | 284340 | 17 | 4 | 49 | |
| GSE54994 | CXCL17 | 284340 | 7 | 12 | 34 | |
| GSE60625 | CXCL17 | 284340 | 9 | 0 | 2 | |
| GSE74703 | CXCL17 | 284340 | 5 | 7 | 24 | |
| GSE74704 | CXCL17 | 284340 | 4 | 2 | 14 | |
| TCGA | CXCL17 | 284340 | 13 | 16 | 67 |
Total number of gains: 124; Total number of losses: 68; Total Number of normals: 296.
Somatic mutations of CXCL17:
Generating mutation plots.
Highly correlated genes for CXCL17:
Showing top 20/1421 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CXCL17 | CLIC3 | 0.80569 | 5 | 0 | 5 |
| CXCL17 | ZDHHC13 | 0.800847 | 7 | 0 | 7 |
| CXCL17 | ALDH9A1 | 0.799284 | 7 | 0 | 7 |
| CXCL17 | FAM3D | 0.78828 | 9 | 0 | 9 |
| CXCL17 | ATP13A4 | 0.787863 | 8 | 0 | 7 |
| CXCL17 | APOBEC1 | 0.78767 | 3 | 0 | 3 |
| CXCL17 | GDPD3 | 0.785025 | 7 | 0 | 7 |
| CXCL17 | SLC13A4 | 0.780738 | 6 | 0 | 6 |
| CXCL17 | BLNK | 0.777156 | 7 | 0 | 7 |
| CXCL17 | SFTA2 | 0.777038 | 4 | 0 | 4 |
| CXCL17 | SLC35C1 | 0.775397 | 6 | 0 | 6 |
| CXCL17 | C5orf66-AS1 | 0.773161 | 6 | 0 | 5 |
| CXCL17 | GPT2 | 0.764189 | 7 | 0 | 7 |
| CXCL17 | CEACAM6 | 0.76313 | 9 | 0 | 9 |
| CXCL17 | LMO7 | 0.762859 | 7 | 0 | 7 |
| CXCL17 | ACAA1 | 0.761829 | 5 | 0 | 5 |
| CXCL17 | KLB | 0.760332 | 6 | 0 | 6 |
| CXCL17 | HLF | 0.760211 | 4 | 0 | 4 |
| CXCL17 | OPHN1 | 0.758013 | 4 | 0 | 4 |
| CXCL17 | NIPAL1 | 0.757023 | 3 | 0 | 3 |
For details and further investigation, click here
