| Full name: sterile alpha motif domain containing 10 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 140700 | HGNC ID: HGNC:16129 | Ensembl Gene: ENSG00000130590 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SAMD10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SAMD10 | 140700 | 227773_at | -0.2601 | 0.3765 | |
| GSE26886 | SAMD10 | 140700 | 227773_at | -0.0352 | 0.8295 | |
| GSE45670 | SAMD10 | 140700 | 233001_at | -0.0341 | 0.7579 | |
| GSE53622 | SAMD10 | 140700 | 136684 | -1.0073 | 0.0000 | |
| GSE53624 | SAMD10 | 140700 | 136684 | -1.1852 | 0.0000 | |
| GSE63941 | SAMD10 | 140700 | 227773_at | 0.3129 | 0.1820 | |
| GSE77861 | SAMD10 | 140700 | 227773_at | -0.0431 | 0.7783 | |
| GSE97050 | SAMD10 | 140700 | A_33_P3403927 | 0.2653 | 0.2874 | |
| SRP007169 | SAMD10 | 140700 | RNAseq | -3.5466 | 0.0000 | |
| SRP008496 | SAMD10 | 140700 | RNAseq | -3.4976 | 0.0000 | |
| SRP064894 | SAMD10 | 140700 | RNAseq | -1.4659 | 0.0000 | |
| SRP133303 | SAMD10 | 140700 | RNAseq | -1.5982 | 0.0000 | |
| SRP159526 | SAMD10 | 140700 | RNAseq | -1.4058 | 0.0048 | |
| SRP193095 | SAMD10 | 140700 | RNAseq | -1.3595 | 0.0000 | |
| TCGA | SAMD10 | 140700 | RNAseq | -0.2170 | 0.0951 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by SAMD10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SAMD10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SAMD10 | 140700 | 13 | 2 | 15 | |
| GSE20123 | SAMD10 | 140700 | 13 | 2 | 15 | |
| GSE43470 | SAMD10 | 140700 | 11 | 1 | 31 | |
| GSE46452 | SAMD10 | 140700 | 35 | 0 | 24 | |
| GSE47630 | SAMD10 | 140700 | 25 | 1 | 14 | |
| GSE54993 | SAMD10 | 140700 | 0 | 17 | 53 | |
| GSE54994 | SAMD10 | 140700 | 29 | 0 | 24 | |
| GSE60625 | SAMD10 | 140700 | 0 | 0 | 11 | |
| GSE74703 | SAMD10 | 140700 | 10 | 0 | 26 | |
| GSE74704 | SAMD10 | 140700 | 10 | 0 | 10 | |
| TCGA | SAMD10 | 140700 | 44 | 4 | 48 |
Total number of gains: 190; Total number of losses: 27; Total Number of normals: 271.
Somatic mutations of SAMD10:
Generating mutation plots.
Highly correlated genes for SAMD10:
Showing top 20/647 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SAMD10 | UPK3B | 0.781735 | 3 | 0 | 3 |
| SAMD10 | GGT6 | 0.758445 | 4 | 0 | 4 |
| SAMD10 | LTA4H | 0.750045 | 3 | 0 | 3 |
| SAMD10 | KLB | 0.737727 | 3 | 0 | 3 |
| SAMD10 | LMO7 | 0.737725 | 4 | 0 | 4 |
| SAMD10 | PLEKHA7 | 0.735144 | 4 | 0 | 4 |
| SAMD10 | ARHGEF10L | 0.734782 | 3 | 0 | 3 |
| SAMD10 | HEBP2 | 0.728086 | 3 | 0 | 3 |
| SAMD10 | TGM1 | 0.724075 | 3 | 0 | 3 |
| SAMD10 | TMEM238 | 0.72094 | 4 | 0 | 4 |
| SAMD10 | ATG9B | 0.71928 | 4 | 0 | 4 |
| SAMD10 | PHLDB3 | 0.718159 | 3 | 0 | 3 |
| SAMD10 | PLEKHM1 | 0.717656 | 3 | 0 | 3 |
| SAMD10 | ZDHHC13 | 0.714649 | 4 | 0 | 4 |
| SAMD10 | NCCRP1 | 0.713819 | 3 | 0 | 3 |
| SAMD10 | DENND2D | 0.711407 | 4 | 0 | 4 |
| SAMD10 | CDK7 | 0.710081 | 3 | 0 | 3 |
| SAMD10 | EPS8L2 | 0.708577 | 3 | 0 | 3 |
| SAMD10 | CTNNBIP1 | 0.70821 | 4 | 0 | 4 |
| SAMD10 | ZFAND2B | 0.707184 | 3 | 0 | 3 |
For details and further investigation, click here
