| Full name: ALG14 UDP-N-acetylglucosaminyltransferase subunit | Alias Symbol: MGC19780 | ||
| Type: protein-coding gene | Cytoband: 1p21.3 | ||
| Entrez ID: 199857 | HGNC ID: HGNC:28287 | Ensembl Gene: ENSG00000172339 | OMIM ID: 612866 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ALG14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALG14 | 199857 | 1553954_at | -0.0815 | 0.9188 | |
| GSE26886 | ALG14 | 199857 | 1553954_at | -1.1209 | 0.0001 | |
| GSE45670 | ALG14 | 199857 | 1553954_at | -0.1571 | 0.3619 | |
| GSE53622 | ALG14 | 199857 | 29769 | -0.2377 | 0.0071 | |
| GSE53624 | ALG14 | 199857 | 29769 | -0.0050 | 0.9617 | |
| GSE63941 | ALG14 | 199857 | 1553954_at | -0.4738 | 0.3445 | |
| GSE77861 | ALG14 | 199857 | 1553954_at | -0.9630 | 0.0020 | |
| GSE97050 | ALG14 | 199857 | A_23_P257423 | 0.0974 | 0.7316 | |
| SRP007169 | ALG14 | 199857 | RNAseq | -0.8836 | 0.0184 | |
| SRP008496 | ALG14 | 199857 | RNAseq | -0.9987 | 0.0001 | |
| SRP064894 | ALG14 | 199857 | RNAseq | 0.2053 | 0.3049 | |
| SRP133303 | ALG14 | 199857 | RNAseq | -0.0788 | 0.4501 | |
| SRP159526 | ALG14 | 199857 | RNAseq | -0.6672 | 0.0004 | |
| SRP193095 | ALG14 | 199857 | RNAseq | -0.1824 | 0.0295 | |
| SRP219564 | ALG14 | 199857 | RNAseq | -0.1016 | 0.7601 | |
| TCGA | ALG14 | 199857 | RNAseq | -0.1983 | 0.0069 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ALG14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALG14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALG14 | 199857 | 0 | 8 | 22 | |
| GSE20123 | ALG14 | 199857 | 0 | 8 | 22 | |
| GSE43470 | ALG14 | 199857 | 2 | 6 | 35 | |
| GSE46452 | ALG14 | 199857 | 1 | 1 | 57 | |
| GSE47630 | ALG14 | 199857 | 8 | 5 | 27 | |
| GSE54993 | ALG14 | 199857 | 0 | 1 | 69 | |
| GSE54994 | ALG14 | 199857 | 6 | 3 | 44 | |
| GSE60625 | ALG14 | 199857 | 0 | 0 | 11 | |
| GSE74703 | ALG14 | 199857 | 1 | 5 | 30 | |
| GSE74704 | ALG14 | 199857 | 0 | 5 | 15 | |
| TCGA | ALG14 | 199857 | 7 | 24 | 65 |
Total number of gains: 25; Total number of losses: 66; Total Number of normals: 397.
Somatic mutations of ALG14:
Generating mutation plots.
Highly correlated genes for ALG14:
Showing top 20/906 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALG14 | ZCCHC9 | 0.830458 | 3 | 0 | 3 |
| ALG14 | WNK1 | 0.811856 | 3 | 0 | 3 |
| ALG14 | UGP2 | 0.804597 | 3 | 0 | 3 |
| ALG14 | HERC4 | 0.788108 | 3 | 0 | 3 |
| ALG14 | TMEM117 | 0.780609 | 3 | 0 | 3 |
| ALG14 | TCAIM | 0.775647 | 3 | 0 | 3 |
| ALG14 | EXOC1 | 0.76493 | 4 | 0 | 4 |
| ALG14 | RASSF5 | 0.754777 | 4 | 0 | 4 |
| ALG14 | NHSL1 | 0.747932 | 3 | 0 | 3 |
| ALG14 | SLC35F5 | 0.745929 | 4 | 0 | 4 |
| ALG14 | TMEM167A | 0.741993 | 3 | 0 | 3 |
| ALG14 | SH3PXD2A | 0.735206 | 3 | 0 | 3 |
| ALG14 | CRYBG3 | 0.734688 | 3 | 0 | 3 |
| ALG14 | EI24 | 0.731241 | 3 | 0 | 3 |
| ALG14 | AK3 | 0.725795 | 3 | 0 | 3 |
| ALG14 | MRPL39 | 0.724257 | 5 | 0 | 4 |
| ALG14 | CRK | 0.722781 | 3 | 0 | 3 |
| ALG14 | SRP9 | 0.722071 | 3 | 0 | 3 |
| ALG14 | KDM2B | 0.721935 | 4 | 0 | 3 |
| ALG14 | MAL2 | 0.72096 | 4 | 0 | 3 |
For details and further investigation, click here
