| Full name: trans-golgi network protein 2 | Alias Symbol: TGN51|TGN46|TGN48|TGN38|TTGN2 | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 10618 | HGNC ID: HGNC:15450 | Ensembl Gene: ENSG00000152291 | OMIM ID: 603062 |
| Drug and gene relationship at DGIdb | |||
Expression of TGOLN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TGOLN2 | 10618 | 212043_at | -0.1504 | 0.7346 | |
| GSE20347 | TGOLN2 | 10618 | 212043_at | 0.2644 | 0.0649 | |
| GSE23400 | TGOLN2 | 10618 | 212043_at | 0.3392 | 0.0014 | |
| GSE26886 | TGOLN2 | 10618 | 212043_at | 0.6299 | 0.0144 | |
| GSE29001 | TGOLN2 | 10618 | 212043_at | 0.3907 | 0.0109 | |
| GSE38129 | TGOLN2 | 10618 | 212043_at | 0.0832 | 0.6715 | |
| GSE45670 | TGOLN2 | 10618 | 212043_at | -0.2399 | 0.2380 | |
| GSE53622 | TGOLN2 | 10618 | 27504 | 0.0987 | 0.1482 | |
| GSE53624 | TGOLN2 | 10618 | 5979 | 0.0481 | 0.4094 | |
| GSE63941 | TGOLN2 | 10618 | 212043_at | -1.2317 | 0.0376 | |
| GSE77861 | TGOLN2 | 10618 | 212043_at | 0.5435 | 0.0614 | |
| GSE97050 | TGOLN2 | 10618 | A_23_P209933 | 0.0618 | 0.7963 | |
| SRP007169 | TGOLN2 | 10618 | RNAseq | 0.9529 | 0.0126 | |
| SRP008496 | TGOLN2 | 10618 | RNAseq | 1.2674 | 0.0000 | |
| SRP064894 | TGOLN2 | 10618 | RNAseq | 0.2107 | 0.2472 | |
| SRP133303 | TGOLN2 | 10618 | RNAseq | 0.2583 | 0.0039 | |
| SRP159526 | TGOLN2 | 10618 | RNAseq | 0.5212 | 0.0183 | |
| SRP193095 | TGOLN2 | 10618 | RNAseq | 0.1846 | 0.2215 | |
| SRP219564 | TGOLN2 | 10618 | RNAseq | 0.0532 | 0.8838 | |
| TCGA | TGOLN2 | 10618 | RNAseq | -0.1718 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by TGOLN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TGOLN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TGOLN2 | 10618 | 9 | 2 | 19 | |
| GSE20123 | TGOLN2 | 10618 | 9 | 2 | 19 | |
| GSE43470 | TGOLN2 | 10618 | 6 | 2 | 35 | |
| GSE46452 | TGOLN2 | 10618 | 2 | 3 | 54 | |
| GSE47630 | TGOLN2 | 10618 | 7 | 0 | 33 | |
| GSE54993 | TGOLN2 | 10618 | 0 | 6 | 64 | |
| GSE54994 | TGOLN2 | 10618 | 10 | 0 | 43 | |
| GSE60625 | TGOLN2 | 10618 | 0 | 3 | 8 | |
| GSE74703 | TGOLN2 | 10618 | 5 | 1 | 30 | |
| GSE74704 | TGOLN2 | 10618 | 7 | 0 | 13 | |
| TCGA | TGOLN2 | 10618 | 36 | 3 | 57 |
Total number of gains: 91; Total number of losses: 22; Total Number of normals: 375.
Somatic mutations of TGOLN2:
Generating mutation plots.
Highly correlated genes for TGOLN2:
Showing top 20/1157 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TGOLN2 | PET117 | 0.81278 | 3 | 0 | 3 |
| TGOLN2 | ASPH | 0.800179 | 3 | 0 | 3 |
| TGOLN2 | SSH1 | 0.791755 | 3 | 0 | 3 |
| TGOLN2 | GNAI1 | 0.776454 | 3 | 0 | 3 |
| TGOLN2 | CNNM3 | 0.760122 | 3 | 0 | 3 |
| TGOLN2 | SMCR8 | 0.758803 | 3 | 0 | 3 |
| TGOLN2 | TMEM17 | 0.749065 | 3 | 0 | 3 |
| TGOLN2 | PRICKLE2 | 0.730716 | 3 | 0 | 3 |
| TGOLN2 | PRELP | 0.726694 | 3 | 0 | 3 |
| TGOLN2 | BIRC6 | 0.725662 | 3 | 0 | 3 |
| TGOLN2 | KIAA0895L | 0.724455 | 3 | 0 | 3 |
| TGOLN2 | NAV1 | 0.720598 | 4 | 0 | 4 |
| TGOLN2 | TP53I13 | 0.717437 | 3 | 0 | 3 |
| TGOLN2 | TMEM60 | 0.712457 | 4 | 0 | 4 |
| TGOLN2 | MED29 | 0.709807 | 4 | 0 | 3 |
| TGOLN2 | AMMECR1L | 0.707618 | 3 | 0 | 3 |
| TGOLN2 | DPYSL2 | 0.70641 | 12 | 0 | 11 |
| TGOLN2 | CNRIP1 | 0.703658 | 6 | 0 | 6 |
| TGOLN2 | PAQR3 | 0.701979 | 3 | 0 | 3 |
| TGOLN2 | TEX9 | 0.700588 | 3 | 0 | 3 |
For details and further investigation, click here
