| Full name: aspartate beta-hydroxylase | Alias Symbol: CASQ2BP1|BAH|JCTN|HAAH | ||
| Type: protein-coding gene | Cytoband: 8q12.3 | ||
| Entrez ID: 444 | HGNC ID: HGNC:757 | Ensembl Gene: ENSG00000198363 | OMIM ID: 600582 |
| Drug and gene relationship at DGIdb | |||
Expression of ASPH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASPH | 444 | 209135_at | 0.4783 | 0.4629 | |
| GSE20347 | ASPH | 444 | 209135_at | 0.6628 | 0.0013 | |
| GSE23400 | ASPH | 444 | 210896_s_at | 0.4397 | 0.0000 | |
| GSE26886 | ASPH | 444 | 209135_at | 0.1792 | 0.2421 | |
| GSE29001 | ASPH | 444 | 209135_at | 0.4231 | 0.0595 | |
| GSE38129 | ASPH | 444 | 209135_at | 0.5562 | 0.0032 | |
| GSE45670 | ASPH | 444 | 209135_at | 0.2278 | 0.2305 | |
| GSE53622 | ASPH | 444 | 62122 | 0.3230 | 0.0000 | |
| GSE53624 | ASPH | 444 | 62122 | 0.4736 | 0.0000 | |
| GSE63941 | ASPH | 444 | 209135_at | -1.7158 | 0.0741 | |
| GSE77861 | ASPH | 444 | 209135_at | 0.3099 | 0.1551 | |
| GSE97050 | ASPH | 444 | A_24_P295245 | 0.1279 | 0.7085 | |
| SRP007169 | ASPH | 444 | RNAseq | 0.1021 | 0.7996 | |
| SRP008496 | ASPH | 444 | RNAseq | 0.8278 | 0.0202 | |
| SRP064894 | ASPH | 444 | RNAseq | 0.4431 | 0.0641 | |
| SRP133303 | ASPH | 444 | RNAseq | 0.4619 | 0.0494 | |
| SRP159526 | ASPH | 444 | RNAseq | 0.5167 | 0.2027 | |
| SRP193095 | ASPH | 444 | RNAseq | 0.4903 | 0.0081 | |
| SRP219564 | ASPH | 444 | RNAseq | 0.2002 | 0.4870 | |
| TCGA | ASPH | 444 | RNAseq | -0.1051 | 0.0799 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ASPH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASPH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASPH | 444 | 13 | 1 | 16 | |
| GSE20123 | ASPH | 444 | 13 | 1 | 16 | |
| GSE43470 | ASPH | 444 | 15 | 3 | 25 | |
| GSE46452 | ASPH | 444 | 20 | 2 | 37 | |
| GSE47630 | ASPH | 444 | 23 | 1 | 16 | |
| GSE54993 | ASPH | 444 | 1 | 18 | 51 | |
| GSE54994 | ASPH | 444 | 30 | 0 | 23 | |
| GSE60625 | ASPH | 444 | 0 | 4 | 7 | |
| GSE74703 | ASPH | 444 | 13 | 2 | 21 | |
| GSE74704 | ASPH | 444 | 9 | 0 | 11 | |
| TCGA | ASPH | 444 | 46 | 6 | 44 |
Total number of gains: 183; Total number of losses: 38; Total Number of normals: 267.
Somatic mutations of ASPH:
Generating mutation plots.
Highly correlated genes for ASPH:
Showing top 20/473 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASPH | TGOLN2 | 0.800179 | 3 | 0 | 3 |
| ASPH | CEP250 | 0.793411 | 3 | 0 | 3 |
| ASPH | UBR1 | 0.767676 | 3 | 0 | 3 |
| ASPH | TMEM65 | 0.74629 | 3 | 0 | 3 |
| ASPH | PHF3 | 0.743655 | 3 | 0 | 3 |
| ASPH | SNRNP48 | 0.741607 | 3 | 0 | 3 |
| ASPH | CDC42SE2 | 0.738262 | 3 | 0 | 3 |
| ASPH | IL18RAP | 0.738058 | 3 | 0 | 3 |
| ASPH | PPP1R21 | 0.735369 | 3 | 0 | 3 |
| ASPH | IMMP1L | 0.729573 | 3 | 0 | 3 |
| ASPH | CISD2 | 0.727821 | 3 | 0 | 3 |
| ASPH | CEP70 | 0.725239 | 3 | 0 | 3 |
| ASPH | PHRF1 | 0.724132 | 3 | 0 | 3 |
| ASPH | RBM22 | 0.721725 | 3 | 0 | 3 |
| ASPH | LYAR | 0.718957 | 3 | 0 | 3 |
| ASPH | AGTRAP | 0.717832 | 3 | 0 | 3 |
| ASPH | ZFYVE26 | 0.708203 | 3 | 0 | 3 |
| ASPH | FEZ1 | 0.706222 | 3 | 0 | 3 |
| ASPH | SLC4A8 | 0.703131 | 3 | 0 | 3 |
| ASPH | SLC22A5 | 0.703059 | 4 | 0 | 3 |
For details and further investigation, click here
