NAV1

 

Full name: neuron navigator 1 Alias Symbol: FLJ12560|FLJ14203|KIAA1151|MGC14961|POMFIL3|steerin-1|DKFZp781D0314
Type: protein-coding gene Cytoband: 1q32.1
Entrez ID: 89796 HGNC ID: HGNC:15989 Ensembl Gene: ENSG00000134369 OMIM ID: 611628
Drug and gene relationship at DGIdb

 

Expression of NAV1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NAV1 89796 224774_s_at 1.2965 0.0476
GSE26886 NAV1 89796 224772_at 1.5554 0.0016
GSE45670 NAV1 89796 224772_at 0.3990 0.2647
GSE53622 NAV1 89796 8432 0.9766 0.0000
GSE53624 NAV1 89796 8432 1.1549 0.0000
GSE63941 NAV1 89796 224772_at -3.3457 0.0046
GSE77861 NAV1 89796 224771_at 1.5652 0.0237
GSE97050 NAV1 89796 A_33_P3405068 0.5634 0.1646
SRP007169 NAV1 89796 RNAseq 3.8737 0.0000
SRP008496 NAV1 89796 RNAseq 3.8414 0.0000
SRP064894 NAV1 89796 RNAseq 1.1647 0.0000
SRP133303 NAV1 89796 RNAseq 1.0358 0.0005
SRP159526 NAV1 89796 RNAseq 2.0515 0.0004
SRP193095 NAV1 89796 RNAseq 1.6172 0.0000
SRP219564 NAV1 89796 RNAseq 0.2622 0.5241
TCGA NAV1 89796 RNAseq 0.3845 0.0001

Upregulated datasets: 10; Downregulated datasets: 1.  


 

Survival by NAV1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of NAV1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NAV1 89796 11 0 19
GSE20123 NAV1 89796 11 0 19
GSE43470 NAV1 89796 6 0 37
GSE46452 NAV1 89796 3 1 55
GSE47630 NAV1 89796 14 0 26
GSE54993 NAV1 89796 0 6 64
GSE54994 NAV1 89796 15 0 38
GSE60625 NAV1 89796 0 0 11
GSE74703 NAV1 89796 6 0 30
GSE74704 NAV1 89796 5 0 15
TCGA NAV1 89796 44 5 47

Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.  


 

Somatic mutations of NAV1:

 

Generating mutation plots.

 

Highly correlated genes for NAV1:

 

Showing top 20/1193 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NAV1TUBA1B0.774722303
NAV1ZC3H7B0.768336303
NAV1RFTN10.735429303
NAV1THOP10.73283404
NAV1SPON20.731764303
NAV1HSD17B10.729742404
NAV1RCN20.724728404
NAV1CLSTN10.722466504
NAV1RILPL20.72184303
NAV1TGOLN20.720598404
NAV1SLC25A220.719492303
NAV1UBB0.71798303
NAV1HES60.717505303
NAV1XPO60.716072505
NAV1ADCY30.715359505
NAV1DPY19L10.714843808
NAV1RNF260.710087403
NAV1MYO5A0.709853808
NAV1IMPDH10.707273403
NAV1PYCR20.705914303

For details and further investigation, click here