| Full name: baculoviral IAP repeat containing 6 | Alias Symbol: BRUCE | ||
| Type: protein-coding gene | Cytoband: 2p22.3 | ||
| Entrez ID: 57448 | HGNC ID: HGNC:13516 | Ensembl Gene: ENSG00000115760 | OMIM ID: 605638 |
| Drug and gene relationship at DGIdb | |||
Expression of BIRC6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BIRC6 | 57448 | 233093_s_at | 0.1582 | 0.4605 | |
| GSE26886 | BIRC6 | 57448 | 233093_s_at | 0.9027 | 0.0000 | |
| GSE45670 | BIRC6 | 57448 | 233093_s_at | -0.0371 | 0.7264 | |
| GSE53622 | BIRC6 | 57448 | 118837 | -0.6131 | 0.0000 | |
| GSE53624 | BIRC6 | 57448 | 118837 | -0.3921 | 0.0000 | |
| GSE63941 | BIRC6 | 57448 | 233093_s_at | -0.5249 | 0.1971 | |
| GSE77861 | BIRC6 | 57448 | 233093_s_at | 0.1623 | 0.3319 | |
| GSE97050 | BIRC6 | 57448 | A_33_P3314902 | -0.4283 | 0.1372 | |
| SRP007169 | BIRC6 | 57448 | RNAseq | 0.2443 | 0.4654 | |
| SRP008496 | BIRC6 | 57448 | RNAseq | 0.3576 | 0.0323 | |
| SRP064894 | BIRC6 | 57448 | RNAseq | -0.1426 | 0.5790 | |
| SRP133303 | BIRC6 | 57448 | RNAseq | 0.0682 | 0.4395 | |
| SRP159526 | BIRC6 | 57448 | RNAseq | -0.1307 | 0.5968 | |
| SRP193095 | BIRC6 | 57448 | RNAseq | 0.0757 | 0.3133 | |
| SRP219564 | BIRC6 | 57448 | RNAseq | -0.2695 | 0.2918 | |
| TCGA | BIRC6 | 57448 | RNAseq | -0.0804 | 0.0547 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BIRC6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BIRC6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BIRC6 | 57448 | 10 | 1 | 19 | |
| GSE20123 | BIRC6 | 57448 | 9 | 1 | 20 | |
| GSE43470 | BIRC6 | 57448 | 2 | 1 | 40 | |
| GSE46452 | BIRC6 | 57448 | 2 | 4 | 53 | |
| GSE47630 | BIRC6 | 57448 | 8 | 0 | 32 | |
| GSE54993 | BIRC6 | 57448 | 0 | 5 | 65 | |
| GSE54994 | BIRC6 | 57448 | 10 | 1 | 42 | |
| GSE60625 | BIRC6 | 57448 | 0 | 3 | 8 | |
| GSE74703 | BIRC6 | 57448 | 2 | 0 | 34 | |
| GSE74704 | BIRC6 | 57448 | 9 | 1 | 10 | |
| TCGA | BIRC6 | 57448 | 36 | 3 | 57 |
Total number of gains: 88; Total number of losses: 20; Total Number of normals: 380.
Somatic mutations of BIRC6:
Generating mutation plots.
Highly correlated genes for BIRC6:
Showing top 20/212 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BIRC6 | QSER1 | 0.867273 | 3 | 0 | 3 |
| BIRC6 | INVS | 0.801665 | 3 | 0 | 3 |
| BIRC6 | CPSF3 | 0.765131 | 4 | 0 | 4 |
| BIRC6 | CYB5D1 | 0.753165 | 3 | 0 | 3 |
| BIRC6 | ANKRD13C | 0.752812 | 3 | 0 | 3 |
| BIRC6 | DIP2A | 0.749569 | 3 | 0 | 3 |
| BIRC6 | NGRN | 0.749207 | 3 | 0 | 3 |
| BIRC6 | A4GALT | 0.747477 | 3 | 0 | 3 |
| BIRC6 | SEL1L3 | 0.74745 | 3 | 0 | 3 |
| BIRC6 | SRXN1 | 0.747048 | 3 | 0 | 3 |
| BIRC6 | CDC42EP3 | 0.74563 | 3 | 0 | 3 |
| BIRC6 | YTHDC2 | 0.738225 | 3 | 0 | 3 |
| BIRC6 | LYRM4 | 0.736551 | 3 | 0 | 3 |
| BIRC6 | CCNT1 | 0.734991 | 3 | 0 | 3 |
| BIRC6 | CPT1A | 0.734984 | 3 | 0 | 3 |
| BIRC6 | CTDSP1 | 0.734579 | 3 | 0 | 3 |
| BIRC6 | CEP120 | 0.734138 | 3 | 0 | 3 |
| BIRC6 | ZACN | 0.730777 | 3 | 0 | 3 |
| BIRC6 | TGOLN2 | 0.725662 | 3 | 0 | 3 |
| BIRC6 | PDGFC | 0.724849 | 3 | 0 | 3 |
For details and further investigation, click here
