| Full name: transmembrane 7 superfamily member 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12p11.23 | ||
| Entrez ID: 51768 | HGNC ID: HGNC:23049 | Ensembl Gene: ENSG00000064115 | OMIM ID: 605181 |
| Drug and gene relationship at DGIdb | |||
Expression of TM7SF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TM7SF3 | 51768 | 222477_s_at | -0.0741 | 0.8820 | |
| GSE20347 | TM7SF3 | 51768 | 217974_at | 0.1128 | 0.7554 | |
| GSE23400 | TM7SF3 | 51768 | 217974_at | -0.1138 | 0.0288 | |
| GSE26886 | TM7SF3 | 51768 | 222477_s_at | -0.3558 | 0.3961 | |
| GSE29001 | TM7SF3 | 51768 | 217974_at | 0.1131 | 0.8107 | |
| GSE38129 | TM7SF3 | 51768 | 217974_at | 0.0751 | 0.7924 | |
| GSE45670 | TM7SF3 | 51768 | 222477_s_at | 0.0180 | 0.9403 | |
| GSE53622 | TM7SF3 | 51768 | 85610 | -0.1431 | 0.1722 | |
| GSE53624 | TM7SF3 | 51768 | 85610 | -0.3008 | 0.0073 | |
| GSE63941 | TM7SF3 | 51768 | 222477_s_at | -0.0837 | 0.8903 | |
| GSE77861 | TM7SF3 | 51768 | 222477_s_at | -0.1621 | 0.6725 | |
| GSE97050 | TM7SF3 | 51768 | A_23_P47857 | -0.3273 | 0.4380 | |
| SRP007169 | TM7SF3 | 51768 | RNAseq | -0.4338 | 0.1662 | |
| SRP008496 | TM7SF3 | 51768 | RNAseq | 0.0953 | 0.7968 | |
| SRP064894 | TM7SF3 | 51768 | RNAseq | -0.3367 | 0.0324 | |
| SRP133303 | TM7SF3 | 51768 | RNAseq | -0.0925 | 0.6893 | |
| SRP159526 | TM7SF3 | 51768 | RNAseq | -0.2997 | 0.0641 | |
| SRP193095 | TM7SF3 | 51768 | RNAseq | -0.3264 | 0.0374 | |
| SRP219564 | TM7SF3 | 51768 | RNAseq | -0.1311 | 0.7528 | |
| TCGA | TM7SF3 | 51768 | RNAseq | -0.0529 | 0.4319 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TM7SF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TM7SF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TM7SF3 | 51768 | 10 | 1 | 19 | |
| GSE20123 | TM7SF3 | 51768 | 10 | 1 | 19 | |
| GSE43470 | TM7SF3 | 51768 | 9 | 4 | 30 | |
| GSE46452 | TM7SF3 | 51768 | 10 | 1 | 48 | |
| GSE47630 | TM7SF3 | 51768 | 14 | 0 | 26 | |
| GSE54993 | TM7SF3 | 51768 | 0 | 9 | 61 | |
| GSE54994 | TM7SF3 | 51768 | 10 | 3 | 40 | |
| GSE60625 | TM7SF3 | 51768 | 0 | 1 | 10 | |
| GSE74703 | TM7SF3 | 51768 | 9 | 3 | 24 | |
| GSE74704 | TM7SF3 | 51768 | 5 | 1 | 14 | |
| TCGA | TM7SF3 | 51768 | 43 | 6 | 47 |
Total number of gains: 120; Total number of losses: 30; Total Number of normals: 338.
Somatic mutations of TM7SF3:
Generating mutation plots.
Highly correlated genes for TM7SF3:
Showing top 20/136 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TM7SF3 | GBGT1 | 0.772255 | 3 | 0 | 3 |
| TM7SF3 | RWDD2A | 0.762851 | 3 | 0 | 3 |
| TM7SF3 | CD200 | 0.759138 | 3 | 0 | 3 |
| TM7SF3 | BBS4 | 0.728153 | 3 | 0 | 3 |
| TM7SF3 | SULT1C2 | 0.725067 | 3 | 0 | 3 |
| TM7SF3 | ZNF862 | 0.719333 | 3 | 0 | 3 |
| TM7SF3 | LRMP | 0.718298 | 3 | 0 | 3 |
| TM7SF3 | TTC17 | 0.715403 | 4 | 0 | 3 |
| TM7SF3 | ANAPC16 | 0.714774 | 4 | 0 | 4 |
| TM7SF3 | SLC35B3 | 0.712415 | 3 | 0 | 3 |
| TM7SF3 | SPATA2 | 0.711793 | 3 | 0 | 3 |
| TM7SF3 | ANXA6 | 0.710657 | 3 | 0 | 3 |
| TM7SF3 | FAM160B1 | 0.707245 | 3 | 0 | 3 |
| TM7SF3 | CELF2 | 0.691147 | 3 | 0 | 3 |
| TM7SF3 | HYLS1 | 0.686178 | 3 | 0 | 3 |
| TM7SF3 | EIF3E | 0.684239 | 3 | 0 | 3 |
| TM7SF3 | CREB3 | 0.681656 | 3 | 0 | 3 |
| TM7SF3 | ATXN7L3B | 0.675388 | 4 | 0 | 3 |
| TM7SF3 | CAMK1 | 0.67135 | 3 | 0 | 3 |
| TM7SF3 | SNX25 | 0.669168 | 4 | 0 | 4 |
For details and further investigation, click here
