| Full name: HYLS1 centriolar and ciliogenesis associated | Alias Symbol: FLJ32915 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 219844 | HGNC ID: HGNC:26558 | Ensembl Gene: ENSG00000198331 | OMIM ID: 610693 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HYLS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HYLS1 | 219844 | 227687_at | 0.5814 | 0.1241 | |
| GSE26886 | HYLS1 | 219844 | 227687_at | -0.1273 | 0.6857 | |
| GSE45670 | HYLS1 | 219844 | 227687_at | 0.4848 | 0.0317 | |
| GSE53622 | HYLS1 | 219844 | 26140 | 0.5783 | 0.0000 | |
| GSE53624 | HYLS1 | 219844 | 26140 | 0.7291 | 0.0000 | |
| GSE63941 | HYLS1 | 219844 | 227687_at | 0.2258 | 0.7726 | |
| GSE77861 | HYLS1 | 219844 | 227687_at | 0.5130 | 0.2461 | |
| GSE97050 | HYLS1 | 219844 | A_23_P127522 | 0.4492 | 0.1702 | |
| SRP007169 | HYLS1 | 219844 | RNAseq | 0.6979 | 0.2386 | |
| SRP008496 | HYLS1 | 219844 | RNAseq | 0.4668 | 0.2326 | |
| SRP064894 | HYLS1 | 219844 | RNAseq | 0.3280 | 0.1081 | |
| SRP133303 | HYLS1 | 219844 | RNAseq | 0.2563 | 0.1588 | |
| SRP159526 | HYLS1 | 219844 | RNAseq | 0.3691 | 0.3247 | |
| SRP193095 | HYLS1 | 219844 | RNAseq | -0.3909 | 0.0053 | |
| SRP219564 | HYLS1 | 219844 | RNAseq | -0.2248 | 0.6522 | |
| TCGA | HYLS1 | 219844 | RNAseq | 0.0891 | 0.3900 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HYLS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HYLS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HYLS1 | 219844 | 0 | 13 | 17 | |
| GSE20123 | HYLS1 | 219844 | 0 | 13 | 17 | |
| GSE43470 | HYLS1 | 219844 | 2 | 7 | 34 | |
| GSE46452 | HYLS1 | 219844 | 3 | 26 | 30 | |
| GSE47630 | HYLS1 | 219844 | 2 | 19 | 19 | |
| GSE54993 | HYLS1 | 219844 | 10 | 0 | 60 | |
| GSE54994 | HYLS1 | 219844 | 5 | 19 | 29 | |
| GSE60625 | HYLS1 | 219844 | 0 | 3 | 8 | |
| GSE74703 | HYLS1 | 219844 | 1 | 5 | 30 | |
| GSE74704 | HYLS1 | 219844 | 0 | 9 | 11 | |
| TCGA | HYLS1 | 219844 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of HYLS1:
Generating mutation plots.
Highly correlated genes for HYLS1:
Showing top 20/1080 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HYLS1 | TM2D3 | 0.812865 | 3 | 0 | 3 |
| HYLS1 | RCN2 | 0.81183 | 3 | 0 | 3 |
| HYLS1 | CTBP2 | 0.798247 | 3 | 0 | 3 |
| HYLS1 | ZNF567 | 0.782588 | 3 | 0 | 3 |
| HYLS1 | MED23 | 0.774415 | 3 | 0 | 3 |
| HYLS1 | RNASEH2B | 0.770139 | 3 | 0 | 3 |
| HYLS1 | ZFYVE27 | 0.766778 | 3 | 0 | 3 |
| HYLS1 | PPP2R1B | 0.753838 | 3 | 0 | 3 |
| HYLS1 | DSCC1 | 0.751093 | 4 | 0 | 4 |
| HYLS1 | FAM98B | 0.74712 | 3 | 0 | 3 |
| HYLS1 | TDG | 0.742853 | 3 | 0 | 3 |
| HYLS1 | NIPAL3 | 0.732138 | 3 | 0 | 3 |
| HYLS1 | EIF3C | 0.730012 | 3 | 0 | 3 |
| HYLS1 | FAM185A | 0.725625 | 3 | 0 | 3 |
| HYLS1 | CCDC14 | 0.723802 | 3 | 0 | 3 |
| HYLS1 | COPS3 | 0.722107 | 3 | 0 | 3 |
| HYLS1 | EP400 | 0.7206 | 4 | 0 | 3 |
| HYLS1 | JTB | 0.717097 | 5 | 0 | 5 |
| HYLS1 | THADA | 0.716001 | 3 | 0 | 3 |
| HYLS1 | AAAS | 0.71517 | 3 | 0 | 3 |
For details and further investigation, click here
