| Full name: transmembrane protein 104 | Alias Symbol: FLJ20255|FLJ00021 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 54868 | HGNC ID: HGNC:25984 | Ensembl Gene: ENSG00000109066 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM104:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM104 | 54868 | 220097_s_at | 0.6605 | 0.0355 | |
| GSE20347 | TMEM104 | 54868 | 220097_s_at | 0.1515 | 0.0800 | |
| GSE23400 | TMEM104 | 54868 | 220097_s_at | 0.1964 | 0.0000 | |
| GSE26886 | TMEM104 | 54868 | 220097_s_at | 0.7092 | 0.0001 | |
| GSE29001 | TMEM104 | 54868 | 220097_s_at | 0.5749 | 0.0105 | |
| GSE38129 | TMEM104 | 54868 | 220097_s_at | 0.0946 | 0.3273 | |
| GSE45670 | TMEM104 | 54868 | 220097_s_at | 0.5064 | 0.0001 | |
| GSE53622 | TMEM104 | 54868 | 88732 | 0.8358 | 0.0000 | |
| GSE53624 | TMEM104 | 54868 | 88732 | 1.0410 | 0.0000 | |
| GSE63941 | TMEM104 | 54868 | 220097_s_at | -0.6459 | 0.0103 | |
| GSE77861 | TMEM104 | 54868 | 220097_s_at | 0.2946 | 0.0261 | |
| GSE97050 | TMEM104 | 54868 | A_24_P284324 | 0.4395 | 0.1476 | |
| SRP007169 | TMEM104 | 54868 | RNAseq | 0.6205 | 0.2275 | |
| SRP008496 | TMEM104 | 54868 | RNAseq | 0.1514 | 0.7072 | |
| SRP064894 | TMEM104 | 54868 | RNAseq | 1.2827 | 0.0000 | |
| SRP133303 | TMEM104 | 54868 | RNAseq | 0.8215 | 0.0002 | |
| SRP159526 | TMEM104 | 54868 | RNAseq | 0.4591 | 0.0859 | |
| SRP193095 | TMEM104 | 54868 | RNAseq | 0.7089 | 0.0000 | |
| SRP219564 | TMEM104 | 54868 | RNAseq | 1.5201 | 0.0088 | |
| TCGA | TMEM104 | 54868 | RNAseq | 0.1049 | 0.0483 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by TMEM104 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM104:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM104 | 54868 | 6 | 2 | 22 | |
| GSE20123 | TMEM104 | 54868 | 6 | 2 | 22 | |
| GSE43470 | TMEM104 | 54868 | 5 | 3 | 35 | |
| GSE46452 | TMEM104 | 54868 | 33 | 0 | 26 | |
| GSE47630 | TMEM104 | 54868 | 8 | 1 | 31 | |
| GSE54993 | TMEM104 | 54868 | 2 | 5 | 63 | |
| GSE54994 | TMEM104 | 54868 | 10 | 4 | 39 | |
| GSE60625 | TMEM104 | 54868 | 6 | 0 | 5 | |
| GSE74703 | TMEM104 | 54868 | 5 | 1 | 30 | |
| GSE74704 | TMEM104 | 54868 | 4 | 1 | 15 | |
| TCGA | TMEM104 | 54868 | 32 | 10 | 54 |
Total number of gains: 117; Total number of losses: 29; Total Number of normals: 342.
Somatic mutations of TMEM104:
Generating mutation plots.
Highly correlated genes for TMEM104:
Showing top 20/498 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM104 | PCBP4 | 0.763551 | 3 | 0 | 3 |
| TMEM104 | ZMYND15 | 0.73688 | 3 | 0 | 3 |
| TMEM104 | FBXL8 | 0.735209 | 3 | 0 | 3 |
| TMEM104 | TANGO2 | 0.725749 | 5 | 0 | 5 |
| TMEM104 | LRWD1 | 0.723638 | 3 | 0 | 3 |
| TMEM104 | BOP1 | 0.713449 | 3 | 0 | 3 |
| TMEM104 | CDC34 | 0.712879 | 3 | 0 | 3 |
| TMEM104 | RFX8 | 0.706663 | 3 | 0 | 3 |
| TMEM104 | RAP2C-AS1 | 0.704799 | 3 | 0 | 3 |
| TMEM104 | APTX | 0.702522 | 6 | 0 | 5 |
| TMEM104 | ATAD3C | 0.701569 | 4 | 0 | 4 |
| TMEM104 | PLBD2 | 0.696596 | 7 | 0 | 7 |
| TMEM104 | UHRF1 | 0.69543 | 6 | 0 | 6 |
| TMEM104 | PRR19 | 0.689118 | 3 | 0 | 3 |
| TMEM104 | CHTF18 | 0.687919 | 4 | 0 | 4 |
| TMEM104 | B4GALNT3 | 0.687193 | 3 | 0 | 3 |
| TMEM104 | FBRSL1 | 0.686048 | 5 | 0 | 4 |
| TMEM104 | TOX2 | 0.685136 | 3 | 0 | 3 |
| TMEM104 | CXorf56 | 0.684238 | 4 | 0 | 4 |
| TMEM104 | RASGRF2 | 0.676917 | 3 | 0 | 3 |
For details and further investigation, click here
