| Full name: prostaglandin F receptor | Alias Symbol: FP | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 5737 | HGNC ID: HGNC:9600 | Ensembl Gene: ENSG00000122420 | OMIM ID: 600563 |
| Drug and gene relationship at DGIdb | |||
PTGFR involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04020 | Calcium signaling pathway | |
| hsa04072 | Phospholipase D signaling pathway |
Expression of PTGFR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTGFR | 5737 | 207177_at | -0.0387 | 0.9602 | |
| GSE20347 | PTGFR | 5737 | 207177_at | -0.1023 | 0.3472 | |
| GSE23400 | PTGFR | 5737 | 207177_at | -0.1701 | 0.0034 | |
| GSE26886 | PTGFR | 5737 | 207177_at | -0.1461 | 0.0971 | |
| GSE29001 | PTGFR | 5737 | 207177_at | -0.1112 | 0.5220 | |
| GSE38129 | PTGFR | 5737 | 207177_at | -0.7686 | 0.0062 | |
| GSE45670 | PTGFR | 5737 | 207177_at | -0.5582 | 0.0108 | |
| GSE53622 | PTGFR | 5737 | 88558 | -0.1874 | 0.1714 | |
| GSE53624 | PTGFR | 5737 | 88558 | 0.1526 | 0.0455 | |
| GSE63941 | PTGFR | 5737 | 207177_at | -3.3654 | 0.0000 | |
| GSE77861 | PTGFR | 5737 | 207177_at | -0.0185 | 0.8684 | |
| GSE97050 | PTGFR | 5737 | A_33_P3358183 | -0.1215 | 0.7761 | |
| SRP133303 | PTGFR | 5737 | RNAseq | -0.0167 | 0.9637 | |
| SRP159526 | PTGFR | 5737 | RNAseq | 1.8013 | 0.0042 | |
| SRP219564 | PTGFR | 5737 | RNAseq | 1.0417 | 0.2824 | |
| TCGA | PTGFR | 5737 | RNAseq | -0.7840 | 0.0058 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by PTGFR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTGFR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTGFR | 5737 | 0 | 7 | 23 | |
| GSE20123 | PTGFR | 5737 | 0 | 7 | 23 | |
| GSE43470 | PTGFR | 5737 | 4 | 2 | 37 | |
| GSE46452 | PTGFR | 5737 | 0 | 1 | 58 | |
| GSE47630 | PTGFR | 5737 | 8 | 6 | 26 | |
| GSE54993 | PTGFR | 5737 | 0 | 0 | 70 | |
| GSE54994 | PTGFR | 5737 | 6 | 3 | 44 | |
| GSE60625 | PTGFR | 5737 | 0 | 0 | 11 | |
| GSE74703 | PTGFR | 5737 | 3 | 2 | 31 | |
| GSE74704 | PTGFR | 5737 | 0 | 4 | 16 | |
| TCGA | PTGFR | 5737 | 8 | 24 | 64 |
Total number of gains: 29; Total number of losses: 56; Total Number of normals: 403.
Somatic mutations of PTGFR:
Generating mutation plots.
Highly correlated genes for PTGFR:
Showing top 20/506 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTGFR | MRGPRF | 0.793801 | 3 | 0 | 3 |
| PTGFR | TMEM140 | 0.740541 | 3 | 0 | 3 |
| PTGFR | PEAK1 | 0.704111 | 4 | 0 | 3 |
| PTGFR | VCAM1 | 0.703383 | 3 | 0 | 3 |
| PTGFR | SYNC | 0.699929 | 6 | 0 | 5 |
| PTGFR | C11orf96 | 0.695508 | 3 | 0 | 3 |
| PTGFR | FRZB | 0.695199 | 6 | 0 | 5 |
| PTGFR | MYEF2 | 0.691765 | 3 | 0 | 3 |
| PTGFR | WFDC1 | 0.691051 | 7 | 0 | 6 |
| PTGFR | RPS6KA6 | 0.689667 | 4 | 0 | 3 |
| PTGFR | FMOD | 0.681268 | 3 | 0 | 3 |
| PTGFR | PDE5A | 0.680278 | 8 | 0 | 6 |
| PTGFR | SCUBE3 | 0.680099 | 3 | 0 | 3 |
| PTGFR | TAGLN3 | 0.675907 | 3 | 0 | 3 |
| PTGFR | TMEM100 | 0.673694 | 7 | 0 | 6 |
| PTGFR | GMPR | 0.671803 | 4 | 0 | 4 |
| PTGFR | PCDH9 | 0.671548 | 7 | 0 | 6 |
| PTGFR | AMPH | 0.669784 | 5 | 0 | 4 |
| PTGFR | PID1 | 0.669094 | 7 | 0 | 6 |
| PTGFR | SHC4 | 0.666028 | 4 | 0 | 3 |
For details and further investigation, click here
