| Full name: transmembrane protein 238 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 388564 | HGNC ID: HGNC:40042 | Ensembl Gene: ENSG00000233493 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM238:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM238 | 388564 | 229938_at | -0.0696 | 0.7192 | |
| GSE26886 | TMEM238 | 388564 | 229938_at | 0.7720 | 0.0000 | |
| GSE45670 | TMEM238 | 388564 | 229938_at | 0.0441 | 0.6662 | |
| GSE53622 | TMEM238 | 388564 | 108617 | -0.5088 | 0.0000 | |
| GSE53624 | TMEM238 | 388564 | 108617 | -0.4380 | 0.0000 | |
| GSE63941 | TMEM238 | 388564 | 229938_at | 0.3551 | 0.0297 | |
| GSE77861 | TMEM238 | 388564 | 229938_at | -0.0263 | 0.8772 | |
| GSE97050 | TMEM238 | 388564 | A_33_P3362153 | 0.4158 | 0.2157 | |
| SRP007169 | TMEM238 | 388564 | RNAseq | -2.1482 | 0.0003 | |
| SRP008496 | TMEM238 | 388564 | RNAseq | -1.7799 | 0.0000 | |
| SRP064894 | TMEM238 | 388564 | RNAseq | -1.0773 | 0.0154 | |
| SRP133303 | TMEM238 | 388564 | RNAseq | -0.5182 | 0.1118 | |
| SRP159526 | TMEM238 | 388564 | RNAseq | -1.3288 | 0.0118 | |
| SRP193095 | TMEM238 | 388564 | RNAseq | -0.9384 | 0.0001 | |
| SRP219564 | TMEM238 | 388564 | RNAseq | -0.2438 | 0.7254 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TMEM238 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TMEM238:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM238 | 388564 | 3 | 4 | 23 | |
| GSE20123 | TMEM238 | 388564 | 3 | 3 | 24 | |
| GSE43470 | TMEM238 | 388564 | 3 | 11 | 29 | |
| GSE46452 | TMEM238 | 388564 | 45 | 1 | 13 | |
| GSE47630 | TMEM238 | 388564 | 8 | 6 | 26 | |
| GSE54993 | TMEM238 | 388564 | 17 | 4 | 49 | |
| GSE54994 | TMEM238 | 388564 | 4 | 13 | 36 | |
| GSE60625 | TMEM238 | 388564 | 9 | 0 | 2 | |
| GSE74703 | TMEM238 | 388564 | 3 | 7 | 26 | |
| GSE74704 | TMEM238 | 388564 | 3 | 1 | 16 | |
| TCGA | TMEM238 | 388564 | 20 | 14 | 62 |
Total number of gains: 118; Total number of losses: 64; Total Number of normals: 306.
Somatic mutations of TMEM238:
Generating mutation plots.
Highly correlated genes for TMEM238:
Showing top 20/123 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM238 | SAMD10 | 0.72094 | 4 | 0 | 4 |
| TMEM238 | AP2S1 | 0.695061 | 3 | 0 | 3 |
| TMEM238 | IGLL1 | 0.685175 | 3 | 0 | 3 |
| TMEM238 | SMPD3 | 0.68164 | 3 | 0 | 3 |
| TMEM238 | C10orf95 | 0.669917 | 3 | 0 | 3 |
| TMEM238 | AP1G2 | 0.668042 | 4 | 0 | 4 |
| TMEM238 | TFR2 | 0.662256 | 3 | 0 | 3 |
| TMEM238 | XPO5 | 0.657013 | 3 | 0 | 3 |
| TMEM238 | B4GALT7 | 0.655382 | 3 | 0 | 3 |
| TMEM238 | ZNF296 | 0.655281 | 5 | 0 | 4 |
| TMEM238 | LINC01191 | 0.651762 | 3 | 0 | 3 |
| TMEM238 | MARVELD2 | 0.646907 | 4 | 0 | 4 |
| TMEM238 | IGSF3 | 0.645202 | 3 | 0 | 3 |
| TMEM238 | OSTM1-AS1 | 0.623969 | 3 | 0 | 3 |
| TMEM238 | SYT5 | 0.621297 | 4 | 0 | 4 |
| TMEM238 | KCNK1 | 0.61943 | 4 | 0 | 4 |
| TMEM238 | SLC25A42 | 0.618861 | 3 | 0 | 3 |
| TMEM238 | ANKRD18A | 0.618626 | 4 | 0 | 3 |
| TMEM238 | UCN2 | 0.618264 | 4 | 0 | 3 |
| TMEM238 | NFKBIB | 0.616205 | 6 | 0 | 5 |
For details and further investigation, click here
