| Full name: synaptotagmin 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 6861 | HGNC ID: HGNC:11513 | Ensembl Gene: ENSG00000129990 | OMIM ID: 600782 |
| Drug and gene relationship at DGIdb | |||
Expression of SYT5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYT5 | 6861 | 206162_x_at | -0.1505 | 0.4507 | |
| GSE20347 | SYT5 | 6861 | 206162_x_at | 0.0291 | 0.6678 | |
| GSE23400 | SYT5 | 6861 | 206161_s_at | -0.1135 | 0.0011 | |
| GSE26886 | SYT5 | 6861 | 206162_x_at | 0.2567 | 0.1050 | |
| GSE29001 | SYT5 | 6861 | 206161_s_at | -0.0311 | 0.8433 | |
| GSE38129 | SYT5 | 6861 | 206162_x_at | 0.0173 | 0.8163 | |
| GSE45670 | SYT5 | 6861 | 206161_s_at | 0.0339 | 0.7289 | |
| GSE53622 | SYT5 | 6861 | 161470 | 0.7891 | 0.0025 | |
| GSE53624 | SYT5 | 6861 | 161470 | 0.7603 | 0.0000 | |
| GSE63941 | SYT5 | 6861 | 206162_x_at | 0.0895 | 0.7522 | |
| GSE77861 | SYT5 | 6861 | 206162_x_at | -0.0059 | 0.9735 | |
| GSE97050 | SYT5 | 6861 | A_23_P78849 | 0.1086 | 0.5806 | |
| SRP133303 | SYT5 | 6861 | RNAseq | -0.1287 | 0.6112 | |
| SRP159526 | SYT5 | 6861 | RNAseq | 0.1113 | 0.8362 | |
| SRP193095 | SYT5 | 6861 | RNAseq | 0.0982 | 0.5347 | |
| SRP219564 | SYT5 | 6861 | RNAseq | 0.1469 | 0.7909 | |
| TCGA | SYT5 | 6861 | RNAseq | -0.7692 | 0.2393 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SYT5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYT5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYT5 | 6861 | 3 | 4 | 23 | |
| GSE20123 | SYT5 | 6861 | 3 | 3 | 24 | |
| GSE43470 | SYT5 | 6861 | 3 | 11 | 29 | |
| GSE46452 | SYT5 | 6861 | 45 | 1 | 13 | |
| GSE47630 | SYT5 | 6861 | 8 | 6 | 26 | |
| GSE54993 | SYT5 | 6861 | 17 | 4 | 49 | |
| GSE54994 | SYT5 | 6861 | 4 | 13 | 36 | |
| GSE60625 | SYT5 | 6861 | 9 | 0 | 2 | |
| GSE74703 | SYT5 | 6861 | 3 | 7 | 26 | |
| GSE74704 | SYT5 | 6861 | 3 | 1 | 16 | |
| TCGA | SYT5 | 6861 | 19 | 14 | 63 |
Total number of gains: 117; Total number of losses: 64; Total Number of normals: 307.
Somatic mutations of SYT5:
Generating mutation plots.
Highly correlated genes for SYT5:
Showing top 20/482 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYT5 | ZNF483 | 0.770527 | 3 | 0 | 3 |
| SYT5 | FBXL18 | 0.728255 | 3 | 0 | 3 |
| SYT5 | PNLIPRP1 | 0.716392 | 3 | 0 | 3 |
| SYT5 | APOBEC1 | 0.701345 | 3 | 0 | 3 |
| SYT5 | SSTR3 | 0.698321 | 5 | 0 | 5 |
| SYT5 | SARDH | 0.691053 | 5 | 0 | 5 |
| SYT5 | PRKCG | 0.690216 | 3 | 0 | 3 |
| SYT5 | TDRD1 | 0.685693 | 3 | 0 | 3 |
| SYT5 | ADRA2B | 0.684994 | 3 | 0 | 3 |
| SYT5 | OBSL1 | 0.683443 | 3 | 0 | 3 |
| SYT5 | PPP1R12C | 0.680834 | 3 | 0 | 3 |
| SYT5 | ISLR2 | 0.679229 | 3 | 0 | 3 |
| SYT5 | HPCA | 0.679018 | 3 | 0 | 3 |
| SYT5 | CXCR5 | 0.677646 | 3 | 0 | 3 |
| SYT5 | MSH4 | 0.676042 | 3 | 0 | 3 |
| SYT5 | CDH23 | 0.674691 | 3 | 0 | 3 |
| SYT5 | MED14OS | 0.673071 | 3 | 0 | 3 |
| SYT5 | CRYGC | 0.672395 | 3 | 0 | 3 |
| SYT5 | EDDM3A | 0.666941 | 3 | 0 | 3 |
| SYT5 | GSN-AS1 | 0.666862 | 3 | 0 | 3 |
For details and further investigation, click here
