| Full name: immunoglobulin superfamily member 3 | Alias Symbol: V8|EWI-3|MGC117164 | ||
| Type: protein-coding gene | Cytoband: 1p13.1 | ||
| Entrez ID: 3321 | HGNC ID: HGNC:5950 | Ensembl Gene: ENSG00000143061 | OMIM ID: 603491 |
| Drug and gene relationship at DGIdb | |||
Expression of IGSF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGSF3 | 3321 | 202421_at | 0.1788 | 0.8713 | |
| GSE20347 | IGSF3 | 3321 | 202421_at | 0.0888 | 0.7010 | |
| GSE23400 | IGSF3 | 3321 | 202421_at | 0.4067 | 0.0001 | |
| GSE26886 | IGSF3 | 3321 | 202421_at | 0.5929 | 0.0065 | |
| GSE29001 | IGSF3 | 3321 | 202421_at | 0.6022 | 0.0111 | |
| GSE38129 | IGSF3 | 3321 | 202421_at | 0.6863 | 0.0059 | |
| GSE45670 | IGSF3 | 3321 | 202421_at | 0.6503 | 0.0013 | |
| GSE53622 | IGSF3 | 3321 | 112097 | 0.6688 | 0.0000 | |
| GSE53624 | IGSF3 | 3321 | 112097 | 0.7550 | 0.0000 | |
| GSE63941 | IGSF3 | 3321 | 202421_at | 4.6130 | 0.0001 | |
| GSE77861 | IGSF3 | 3321 | 202421_at | 0.4755 | 0.0219 | |
| GSE97050 | IGSF3 | A_21_P0011816 | 0.7399 | 0.2828 | ||
| SRP007169 | IGSF3 | 3321 | RNAseq | 1.3782 | 0.0033 | |
| SRP008496 | IGSF3 | 3321 | RNAseq | 1.1108 | 0.0004 | |
| SRP064894 | IGSF3 | 3321 | RNAseq | 0.7961 | 0.0364 | |
| SRP133303 | IGSF3 | 3321 | RNAseq | 0.5211 | 0.0430 | |
| SRP159526 | IGSF3 | 3321 | RNAseq | 0.0549 | 0.8689 | |
| SRP193095 | IGSF3 | 3321 | RNAseq | 0.4709 | 0.0197 | |
| SRP219564 | IGSF3 | 3321 | RNAseq | 0.4884 | 0.5421 | |
| TCGA | IGSF3 | 3321 | RNAseq | 0.3072 | 0.0004 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by IGSF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGSF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGSF3 | 3321 | 0 | 9 | 21 | |
| GSE20123 | IGSF3 | 3321 | 0 | 9 | 21 | |
| GSE43470 | IGSF3 | 3321 | 0 | 5 | 38 | |
| GSE46452 | IGSF3 | 3321 | 2 | 1 | 56 | |
| GSE47630 | IGSF3 | 3321 | 9 | 5 | 26 | |
| GSE54993 | IGSF3 | 3321 | 0 | 1 | 69 | |
| GSE54994 | IGSF3 | 3321 | 10 | 2 | 41 | |
| GSE60625 | IGSF3 | 3321 | 0 | 0 | 11 | |
| GSE74703 | IGSF3 | 3321 | 0 | 4 | 32 | |
| GSE74704 | IGSF3 | 3321 | 0 | 5 | 15 | |
| TCGA | IGSF3 | 3321 | 14 | 28 | 54 |
Total number of gains: 35; Total number of losses: 69; Total Number of normals: 384.
Somatic mutations of IGSF3:
Generating mutation plots.
Highly correlated genes for IGSF3:
Showing top 20/405 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGSF3 | CDCA7L | 0.684133 | 3 | 0 | 3 |
| IGSF3 | PPP1R35 | 0.681275 | 3 | 0 | 3 |
| IGSF3 | EML6 | 0.672133 | 4 | 0 | 3 |
| IGSF3 | PAK6 | 0.670134 | 3 | 0 | 3 |
| IGSF3 | RCC2 | 0.660434 | 5 | 0 | 5 |
| IGSF3 | PPP1R14C | 0.655823 | 8 | 0 | 7 |
| IGSF3 | TRAF3 | 0.653096 | 4 | 0 | 3 |
| IGSF3 | CHST13 | 0.649515 | 3 | 0 | 3 |
| IGSF3 | TMEM238 | 0.645202 | 3 | 0 | 3 |
| IGSF3 | PLAGL2 | 0.644728 | 4 | 0 | 4 |
| IGSF3 | ENOX2 | 0.643488 | 4 | 0 | 4 |
| IGSF3 | NOL9 | 0.642198 | 3 | 0 | 3 |
| IGSF3 | CDH1 | 0.642137 | 7 | 0 | 5 |
| IGSF3 | COL7A1 | 0.640481 | 8 | 0 | 8 |
| IGSF3 | IRF6 | 0.639513 | 9 | 0 | 6 |
| IGSF3 | TENM2 | 0.638982 | 5 | 0 | 5 |
| IGSF3 | BSG | 0.637752 | 4 | 0 | 3 |
| IGSF3 | MIR142 | 0.633869 | 3 | 0 | 3 |
| IGSF3 | MARVELD3 | 0.631621 | 5 | 0 | 5 |
| IGSF3 | GRHL2 | 0.629962 | 6 | 0 | 4 |
For details and further investigation, click here
