| Full name: kelch repeat and BTB domain containing 7 | Alias Symbol: DKFZP434E2318 | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 84078 | HGNC ID: HGNC:25266 | Ensembl Gene: ENSG00000120696 | OMIM ID: 617739 |
| Drug and gene relationship at DGIdb | |||
Expression of KBTBD7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KBTBD7 | 84078 | 223412_at | 0.7549 | 0.2312 | |
| GSE26886 | KBTBD7 | 84078 | 229298_at | -0.1654 | 0.6240 | |
| GSE45670 | KBTBD7 | 84078 | 223412_at | 0.2143 | 0.3440 | |
| GSE53622 | KBTBD7 | 84078 | 8486 | 0.0181 | 0.8986 | |
| GSE53624 | KBTBD7 | 84078 | 8486 | 0.0864 | 0.5058 | |
| GSE63941 | KBTBD7 | 84078 | 223412_at | -0.5918 | 0.2234 | |
| GSE77861 | KBTBD7 | 84078 | 223412_at | 0.2338 | 0.4475 | |
| GSE97050 | KBTBD7 | 84078 | A_23_P25605 | -0.0328 | 0.9261 | |
| SRP007169 | KBTBD7 | 84078 | RNAseq | -0.2871 | 0.5201 | |
| SRP008496 | KBTBD7 | 84078 | RNAseq | -0.1513 | 0.6034 | |
| SRP064894 | KBTBD7 | 84078 | RNAseq | 0.2379 | 0.2952 | |
| SRP133303 | KBTBD7 | 84078 | RNAseq | -0.2797 | 0.1341 | |
| SRP159526 | KBTBD7 | 84078 | RNAseq | 0.0627 | 0.8083 | |
| SRP193095 | KBTBD7 | 84078 | RNAseq | -0.2631 | 0.0108 | |
| SRP219564 | KBTBD7 | 84078 | RNAseq | 0.1340 | 0.6600 | |
| TCGA | KBTBD7 | 84078 | RNAseq | -0.1180 | 0.1269 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KBTBD7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KBTBD7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KBTBD7 | 84078 | 0 | 14 | 16 | |
| GSE20123 | KBTBD7 | 84078 | 0 | 13 | 17 | |
| GSE43470 | KBTBD7 | 84078 | 3 | 13 | 27 | |
| GSE46452 | KBTBD7 | 84078 | 0 | 33 | 26 | |
| GSE47630 | KBTBD7 | 84078 | 2 | 27 | 11 | |
| GSE54993 | KBTBD7 | 84078 | 12 | 2 | 56 | |
| GSE54994 | KBTBD7 | 84078 | 1 | 16 | 36 | |
| GSE60625 | KBTBD7 | 84078 | 0 | 3 | 8 | |
| GSE74703 | KBTBD7 | 84078 | 3 | 10 | 23 | |
| GSE74704 | KBTBD7 | 84078 | 0 | 10 | 10 | |
| TCGA | KBTBD7 | 84078 | 7 | 40 | 49 |
Total number of gains: 28; Total number of losses: 181; Total Number of normals: 279.
Somatic mutations of KBTBD7:
Generating mutation plots.
Highly correlated genes for KBTBD7:
Showing top 20/522 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KBTBD7 | SLC25A44 | 0.767748 | 3 | 0 | 3 |
| KBTBD7 | KBTBD6 | 0.761245 | 9 | 0 | 9 |
| KBTBD7 | KLHL8 | 0.759371 | 3 | 0 | 3 |
| KBTBD7 | NUDT3 | 0.751901 | 3 | 0 | 3 |
| KBTBD7 | MRPL9 | 0.751544 | 3 | 0 | 3 |
| KBTBD7 | ZMAT3 | 0.7492 | 3 | 0 | 3 |
| KBTBD7 | UBTD2 | 0.743451 | 3 | 0 | 3 |
| KBTBD7 | SNX30 | 0.743419 | 3 | 0 | 3 |
| KBTBD7 | DNAJC11 | 0.740526 | 3 | 0 | 3 |
| KBTBD7 | TMED8 | 0.736595 | 3 | 0 | 3 |
| KBTBD7 | FAM20B | 0.731783 | 4 | 0 | 4 |
| KBTBD7 | OCRL | 0.727694 | 3 | 0 | 3 |
| KBTBD7 | DIS3L | 0.727567 | 3 | 0 | 3 |
| KBTBD7 | RPL8 | 0.723349 | 3 | 0 | 3 |
| KBTBD7 | AZIN1 | 0.719202 | 4 | 0 | 3 |
| KBTBD7 | CRNKL1 | 0.716507 | 3 | 0 | 3 |
| KBTBD7 | VPS72 | 0.716347 | 3 | 0 | 3 |
| KBTBD7 | USP22 | 0.713751 | 4 | 0 | 3 |
| KBTBD7 | RPUSD4 | 0.711786 | 3 | 0 | 3 |
| KBTBD7 | TMEM117 | 0.711002 | 3 | 0 | 3 |
For details and further investigation, click here
