ACBD6

 

Full name: acyl-CoA binding domain containing 6 Alias Symbol: MGC2404
Type: protein-coding gene Cytoband: 1q25.2-q25.3
Entrez ID: 84320 HGNC ID: HGNC:23339 Ensembl Gene: ENSG00000230124 OMIM ID: 616352
Drug and gene relationship at DGIdb

 

Expression of ACBD6:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ACBD6 84320 225317_at 0.5185 0.1242
GSE26886 ACBD6 84320 225317_at 1.1908 0.0000
GSE45670 ACBD6 84320 225317_at 0.0594 0.7491
GSE53622 ACBD6 84320 29694 0.5164 0.0000
GSE53624 ACBD6 84320 29694 0.5154 0.0000
GSE63941 ACBD6 84320 225317_at -0.5816 0.0861
GSE77861 ACBD6 84320 225317_at 0.5787 0.0098
GSE97050 ACBD6 84320 A_23_P52127 0.3623 0.1675
SRP007169 ACBD6 84320 RNAseq 0.4554 0.3799
SRP008496 ACBD6 84320 RNAseq 0.5659 0.1782
SRP064894 ACBD6 84320 RNAseq 0.6843 0.0019
SRP133303 ACBD6 84320 RNAseq 0.5858 0.0009
SRP159526 ACBD6 84320 RNAseq 0.9931 0.0000
SRP193095 ACBD6 84320 RNAseq 0.5998 0.0000
SRP219564 ACBD6 84320 RNAseq 0.7125 0.0659
TCGA ACBD6 84320 RNAseq 0.2417 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by ACBD6 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ACBD6:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ACBD6 84320 12 0 18
GSE20123 ACBD6 84320 12 0 18
GSE43470 ACBD6 84320 7 1 35
GSE46452 ACBD6 84320 3 1 55
GSE47630 ACBD6 84320 14 0 26
GSE54993 ACBD6 84320 0 6 64
GSE54994 ACBD6 84320 15 0 38
GSE60625 ACBD6 84320 0 0 11
GSE74703 ACBD6 84320 7 1 28
GSE74704 ACBD6 84320 5 0 15
TCGA ACBD6 84320 40 3 53

Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.  


 

Somatic mutations of ACBD6:

 

Generating mutation plots.

 

Highly correlated genes for ACBD6:

 

Showing top 20/1437 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ACBD6USP210.831207303
ACBD6UBQLN40.830204404
ACBD6ALKBH60.821695404
ACBD6NOL90.81934303
ACBD6BRD90.819314303
ACBD6LTBR0.810314303
ACBD6GNS0.806812303
ACBD6CPT1A0.797161303
ACBD6U2SURP0.793978404
ACBD6KDM5A0.793454303
ACBD6RNF1300.792521303
ACBD6PLCG10.783258303
ACBD6SARS20.77489303
ACBD6ABCD40.772165303
ACBD6NADK0.772089303
ACBD6RAD23A0.769545404
ACBD6MAP3K110.768669404
ACBD6SLC25A290.768052303
ACBD6RIMKLB0.767583303
ACBD6PTOV10.765013303

For details and further investigation, click here