| Full name: component of oligomeric golgi complex 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q42.2 | ||
| Entrez ID: 22796 | HGNC ID: HGNC:6546 | Ensembl Gene: ENSG00000135775 | OMIM ID: 606974 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COG2 | 22796 | 203073_at | 0.7183 | 0.0501 | |
| GSE20347 | COG2 | 22796 | 203073_at | 0.5095 | 0.0000 | |
| GSE23400 | COG2 | 22796 | 203073_at | 0.3386 | 0.0000 | |
| GSE26886 | COG2 | 22796 | 203073_at | 0.9682 | 0.0003 | |
| GSE29001 | COG2 | 22796 | 203073_at | 0.5946 | 0.0111 | |
| GSE38129 | COG2 | 22796 | 203073_at | 0.6001 | 0.0000 | |
| GSE45670 | COG2 | 22796 | 203073_at | 0.3067 | 0.0396 | |
| GSE53622 | COG2 | 22796 | 17709 | 0.3885 | 0.0000 | |
| GSE53624 | COG2 | 22796 | 17709 | 0.4618 | 0.0000 | |
| GSE63941 | COG2 | 22796 | 203073_at | 0.1481 | 0.7195 | |
| GSE77861 | COG2 | 22796 | 203073_at | 0.5176 | 0.0320 | |
| GSE97050 | COG2 | 22796 | A_23_P160809 | 0.4137 | 0.1633 | |
| SRP007169 | COG2 | 22796 | RNAseq | 0.3294 | 0.4349 | |
| SRP008496 | COG2 | 22796 | RNAseq | 0.4395 | 0.1350 | |
| SRP064894 | COG2 | 22796 | RNAseq | 0.3203 | 0.0019 | |
| SRP133303 | COG2 | 22796 | RNAseq | 0.3442 | 0.0075 | |
| SRP159526 | COG2 | 22796 | RNAseq | 0.4585 | 0.1341 | |
| SRP193095 | COG2 | 22796 | RNAseq | 0.0024 | 0.9846 | |
| SRP219564 | COG2 | 22796 | RNAseq | 0.7120 | 0.0549 | |
| TCGA | COG2 | 22796 | RNAseq | -0.0701 | 0.1767 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COG2 | 22796 | 11 | 0 | 19 | |
| GSE20123 | COG2 | 22796 | 11 | 0 | 19 | |
| GSE43470 | COG2 | 22796 | 8 | 1 | 34 | |
| GSE46452 | COG2 | 22796 | 4 | 2 | 53 | |
| GSE47630 | COG2 | 22796 | 15 | 0 | 25 | |
| GSE54993 | COG2 | 22796 | 0 | 6 | 64 | |
| GSE54994 | COG2 | 22796 | 17 | 0 | 36 | |
| GSE60625 | COG2 | 22796 | 0 | 0 | 11 | |
| GSE74703 | COG2 | 22796 | 8 | 1 | 27 | |
| GSE74704 | COG2 | 22796 | 5 | 0 | 15 | |
| TCGA | COG2 | 22796 | 45 | 3 | 48 |
Total number of gains: 124; Total number of losses: 13; Total Number of normals: 351.
Somatic mutations of COG2:
Generating mutation plots.
Highly correlated genes for COG2:
Showing top 20/1953 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COG2 | C1orf131 | 0.821059 | 8 | 0 | 8 |
| COG2 | METTL23 | 0.794181 | 6 | 0 | 6 |
| COG2 | FLVCR1 | 0.773089 | 7 | 0 | 7 |
| COG2 | GORAB | 0.761765 | 7 | 0 | 7 |
| COG2 | PYCR2 | 0.760365 | 3 | 0 | 3 |
| COG2 | HERC2 | 0.757054 | 3 | 0 | 3 |
| COG2 | ZNF512 | 0.756887 | 3 | 0 | 3 |
| COG2 | KTI12 | 0.756455 | 3 | 0 | 3 |
| COG2 | ANAPC1 | 0.751851 | 3 | 0 | 3 |
| COG2 | SLC35B2 | 0.746285 | 3 | 0 | 3 |
| COG2 | NVL | 0.742031 | 13 | 0 | 12 |
| COG2 | B3GALT6 | 0.741448 | 5 | 0 | 5 |
| COG2 | ZC3H12C | 0.739012 | 3 | 0 | 3 |
| COG2 | DESI2 | 0.738594 | 10 | 0 | 9 |
| COG2 | HNRNPUL1 | 0.737213 | 3 | 0 | 3 |
| COG2 | CCDC15 | 0.736961 | 3 | 0 | 3 |
| COG2 | C12orf57 | 0.735864 | 4 | 0 | 4 |
| COG2 | SNRPE | 0.733037 | 10 | 0 | 9 |
| COG2 | LIN9 | 0.730683 | 8 | 0 | 7 |
| COG2 | DCAF7 | 0.72918 | 4 | 0 | 4 |
For details and further investigation, click here
