| Full name: homeobox D13 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 3239 | HGNC ID: HGNC:5136 | Ensembl Gene: ENSG00000128714 | OMIM ID: 142989 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of HOXD13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXD13 | 3239 | 236681_at | 1.0376 | 0.0856 | |
| GSE20347 | HOXD13 | 3239 | 207398_at | 0.1065 | 0.1653 | |
| GSE23400 | HOXD13 | 3239 | 207398_at | -0.0231 | 0.5724 | |
| GSE26886 | HOXD13 | 3239 | 236681_at | 1.5577 | 0.0000 | |
| GSE29001 | HOXD13 | 3239 | 207398_at | 0.0651 | 0.6092 | |
| GSE38129 | HOXD13 | 3239 | 207398_at | 0.1333 | 0.0639 | |
| GSE45670 | HOXD13 | 3239 | 236681_at | 0.9467 | 0.0017 | |
| GSE53622 | HOXD13 | 3239 | 12713 | 3.8471 | 0.0000 | |
| GSE53624 | HOXD13 | 3239 | 12713 | 4.9151 | 0.0000 | |
| GSE63941 | HOXD13 | 3239 | 236681_at | 0.8959 | 0.2039 | |
| GSE77861 | HOXD13 | 3239 | 236681_at | 0.4090 | 0.0250 | |
| SRP007169 | HOXD13 | 3239 | RNAseq | 6.1477 | 0.0000 | |
| SRP008496 | HOXD13 | 3239 | RNAseq | 4.9697 | 0.0000 | |
| SRP133303 | HOXD13 | 3239 | RNAseq | 4.0280 | 0.0000 | |
| SRP159526 | HOXD13 | 3239 | RNAseq | 8.0065 | 0.0000 | |
| TCGA | HOXD13 | 3239 | RNAseq | 3.4936 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by HOXD13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXD13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXD13 | 3239 | 9 | 0 | 21 | |
| GSE20123 | HOXD13 | 3239 | 9 | 0 | 21 | |
| GSE43470 | HOXD13 | 3239 | 5 | 1 | 37 | |
| GSE46452 | HOXD13 | 3239 | 1 | 4 | 54 | |
| GSE47630 | HOXD13 | 3239 | 4 | 4 | 32 | |
| GSE54993 | HOXD13 | 3239 | 0 | 5 | 65 | |
| GSE54994 | HOXD13 | 3239 | 11 | 4 | 38 | |
| GSE60625 | HOXD13 | 3239 | 0 | 3 | 8 | |
| GSE74703 | HOXD13 | 3239 | 4 | 1 | 31 | |
| GSE74704 | HOXD13 | 3239 | 5 | 0 | 15 | |
| TCGA | HOXD13 | 3239 | 28 | 5 | 63 |
Total number of gains: 76; Total number of losses: 27; Total Number of normals: 385.
Somatic mutations of HOXD13:
Generating mutation plots.
Highly correlated genes for HOXD13:
Showing top 20/1112 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXD13 | TMEM63B | 0.782006 | 3 | 0 | 3 |
| HOXD13 | PLXNA1 | 0.745636 | 6 | 0 | 6 |
| HOXD13 | KHSRP | 0.740443 | 5 | 0 | 5 |
| HOXD13 | MTBP | 0.733319 | 4 | 0 | 4 |
| HOXD13 | NOP14 | 0.728687 | 4 | 0 | 3 |
| HOXD13 | ALKBH6 | 0.717649 | 4 | 0 | 4 |
| HOXD13 | COLGALT1 | 0.716198 | 6 | 0 | 6 |
| HOXD13 | U2SURP | 0.701825 | 5 | 0 | 5 |
| HOXD13 | MARK4 | 0.701654 | 4 | 0 | 3 |
| HOXD13 | KLHL35 | 0.699271 | 3 | 0 | 3 |
| HOXD13 | UBAP2L | 0.698228 | 4 | 0 | 4 |
| HOXD13 | UBE2Q1 | 0.693973 | 3 | 0 | 3 |
| HOXD13 | DNAJB11 | 0.692353 | 5 | 0 | 4 |
| HOXD13 | GTSE1 | 0.684922 | 7 | 0 | 7 |
| HOXD13 | CHD1L | 0.681785 | 5 | 0 | 4 |
| HOXD13 | STK3 | 0.680351 | 6 | 0 | 6 |
| HOXD13 | DTX3 | 0.679536 | 3 | 0 | 3 |
| HOXD13 | RHPN2 | 0.679505 | 4 | 0 | 3 |
| HOXD13 | SLC26A11 | 0.677507 | 3 | 0 | 3 |
| HOXD13 | PNPT1 | 0.67415 | 5 | 0 | 5 |
For details and further investigation, click here
