| Full name: tetratricopeptide repeat domain 12 | Alias Symbol: FLJ13859|FLJ20535|TPARM | ||
| Type: protein-coding gene | Cytoband: 11q23.2 | ||
| Entrez ID: 54970 | HGNC ID: HGNC:23700 | Ensembl Gene: ENSG00000149292 | OMIM ID: 610732 |
| Drug and gene relationship at DGIdb | |||
Expression of TTC12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC12 | 54970 | 219587_at | -0.2368 | 0.3653 | |
| GSE20347 | TTC12 | 54970 | 219587_at | -0.1871 | 0.0327 | |
| GSE23400 | TTC12 | 54970 | 219587_at | -0.1477 | 0.0022 | |
| GSE26886 | TTC12 | 54970 | 219587_at | 0.1616 | 0.6491 | |
| GSE29001 | TTC12 | 54970 | 219587_at | -0.2906 | 0.2731 | |
| GSE38129 | TTC12 | 54970 | 219587_at | -0.2594 | 0.0025 | |
| GSE45670 | TTC12 | 54970 | 219587_at | -0.1434 | 0.4118 | |
| GSE53622 | TTC12 | 54970 | 65703 | 0.0922 | 0.3420 | |
| GSE53624 | TTC12 | 54970 | 65703 | 0.3189 | 0.0011 | |
| GSE63941 | TTC12 | 54970 | 219587_at | 0.7384 | 0.1917 | |
| GSE77861 | TTC12 | 54970 | 1554531_at | -0.0111 | 0.9361 | |
| GSE97050 | TTC12 | 54970 | A_23_P24535 | -0.0611 | 0.7535 | |
| SRP007169 | TTC12 | 54970 | RNAseq | 0.3021 | 0.6432 | |
| SRP064894 | TTC12 | 54970 | RNAseq | -0.4695 | 0.0036 | |
| SRP133303 | TTC12 | 54970 | RNAseq | -0.8469 | 0.0000 | |
| SRP159526 | TTC12 | 54970 | RNAseq | -0.3980 | 0.2679 | |
| SRP193095 | TTC12 | 54970 | RNAseq | -0.4985 | 0.0010 | |
| SRP219564 | TTC12 | 54970 | RNAseq | -0.6670 | 0.1322 | |
| TCGA | TTC12 | 54970 | RNAseq | -0.2522 | 0.0066 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TTC12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC12 | 54970 | 0 | 13 | 17 | |
| GSE20123 | TTC12 | 54970 | 0 | 13 | 17 | |
| GSE43470 | TTC12 | 54970 | 2 | 6 | 35 | |
| GSE46452 | TTC12 | 54970 | 3 | 26 | 30 | |
| GSE47630 | TTC12 | 54970 | 2 | 19 | 19 | |
| GSE54993 | TTC12 | 54970 | 10 | 0 | 60 | |
| GSE54994 | TTC12 | 54970 | 5 | 19 | 29 | |
| GSE60625 | TTC12 | 54970 | 0 | 3 | 8 | |
| GSE74703 | TTC12 | 54970 | 1 | 4 | 31 | |
| GSE74704 | TTC12 | 54970 | 0 | 9 | 11 | |
| TCGA | TTC12 | 54970 | 5 | 49 | 42 |
Total number of gains: 28; Total number of losses: 161; Total Number of normals: 299.
Somatic mutations of TTC12:
Generating mutation plots.
Highly correlated genes for TTC12:
Showing top 20/133 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC12 | DCDC1 | 0.837501 | 3 | 0 | 3 |
| TTC12 | FBRSL1 | 0.835346 | 3 | 0 | 3 |
| TTC12 | SPACA3 | 0.816056 | 3 | 0 | 3 |
| TTC12 | OR2T27 | 0.811778 | 3 | 0 | 3 |
| TTC12 | PLA2G2C | 0.801966 | 3 | 0 | 3 |
| TTC12 | CHST10 | 0.801034 | 3 | 0 | 3 |
| TTC12 | TRPM8 | 0.793305 | 3 | 0 | 3 |
| TTC12 | MRGPRG | 0.787175 | 3 | 0 | 3 |
| TTC12 | LHX9 | 0.784771 | 3 | 0 | 3 |
| TTC12 | TNNI2 | 0.782992 | 3 | 0 | 3 |
| TTC12 | BBC3 | 0.780685 | 3 | 0 | 3 |
| TTC12 | INSC | 0.778386 | 3 | 0 | 3 |
| TTC12 | TXNDC2 | 0.777566 | 3 | 0 | 3 |
| TTC12 | STRC | 0.774167 | 3 | 0 | 3 |
| TTC12 | CNOT3 | 0.770772 | 3 | 0 | 3 |
| TTC12 | FOXA3 | 0.766026 | 3 | 0 | 3 |
| TTC12 | C2CD4D | 0.762295 | 3 | 0 | 3 |
| TTC12 | C19orf71 | 0.759875 | 3 | 0 | 3 |
| TTC12 | WDR87 | 0.75952 | 3 | 0 | 3 |
| TTC12 | NPPB | 0.756745 | 3 | 0 | 3 |
For details and further investigation, click here
