| Full name: transportin 2 | Alias Symbol: IPO3|KPNB2B|FLJ12155|TRN2 | ||
| Type: protein-coding gene | Cytoband: 19p13.13 | ||
| Entrez ID: 30000 | HGNC ID: HGNC:19998 | Ensembl Gene: ENSG00000105576 | OMIM ID: 603002 |
| Drug and gene relationship at DGIdb | |||
Expression of TNPO2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNPO2 | 30000 | 221506_s_at | 0.4635 | 0.2361 | |
| GSE20347 | TNPO2 | 30000 | 221506_s_at | 0.5427 | 0.0006 | |
| GSE23400 | TNPO2 | 30000 | 221506_s_at | 0.3731 | 0.0000 | |
| GSE26886 | TNPO2 | 30000 | 221506_s_at | 0.9842 | 0.0000 | |
| GSE29001 | TNPO2 | 30000 | 221506_s_at | 0.5113 | 0.0777 | |
| GSE38129 | TNPO2 | 30000 | 221506_s_at | 0.3002 | 0.0877 | |
| GSE45670 | TNPO2 | 30000 | 221506_s_at | 0.1682 | 0.2170 | |
| GSE53622 | TNPO2 | 30000 | 19946 | -0.2304 | 0.0001 | |
| GSE53624 | TNPO2 | 30000 | 19946 | 0.0880 | 0.2040 | |
| GSE63941 | TNPO2 | 30000 | 221506_s_at | 0.2267 | 0.5311 | |
| GSE77861 | TNPO2 | 30000 | 221506_s_at | 0.6020 | 0.0123 | |
| GSE97050 | TNPO2 | 30000 | A_33_P3423300 | -0.2353 | 0.2579 | |
| SRP007169 | TNPO2 | 30000 | RNAseq | 0.6954 | 0.0846 | |
| SRP008496 | TNPO2 | 30000 | RNAseq | 0.7582 | 0.0171 | |
| SRP064894 | TNPO2 | 30000 | RNAseq | 0.4202 | 0.0222 | |
| SRP133303 | TNPO2 | 30000 | RNAseq | 0.1424 | 0.3475 | |
| SRP159526 | TNPO2 | 30000 | RNAseq | 0.2203 | 0.5281 | |
| SRP193095 | TNPO2 | 30000 | RNAseq | 0.2304 | 0.0551 | |
| SRP219564 | TNPO2 | 30000 | RNAseq | 0.1998 | 0.6068 | |
| TCGA | TNPO2 | 30000 | RNAseq | 0.0221 | 0.6237 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNPO2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNPO2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNPO2 | 30000 | 4 | 2 | 24 | |
| GSE20123 | TNPO2 | 30000 | 3 | 1 | 26 | |
| GSE43470 | TNPO2 | 30000 | 2 | 6 | 35 | |
| GSE46452 | TNPO2 | 30000 | 47 | 1 | 11 | |
| GSE47630 | TNPO2 | 30000 | 4 | 7 | 29 | |
| GSE54993 | TNPO2 | 30000 | 16 | 3 | 51 | |
| GSE54994 | TNPO2 | 30000 | 6 | 13 | 34 | |
| GSE60625 | TNPO2 | 30000 | 9 | 0 | 2 | |
| GSE74703 | TNPO2 | 30000 | 2 | 4 | 30 | |
| GSE74704 | TNPO2 | 30000 | 0 | 1 | 19 | |
| TCGA | TNPO2 | 30000 | 16 | 13 | 67 |
Total number of gains: 109; Total number of losses: 51; Total Number of normals: 328.
Somatic mutations of TNPO2:
Generating mutation plots.
Highly correlated genes for TNPO2:
Showing top 20/698 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNPO2 | RAD23A | 0.757799 | 9 | 0 | 9 |
| TNPO2 | ZNF558 | 0.748309 | 4 | 0 | 4 |
| TNPO2 | DAB2IP | 0.741231 | 3 | 0 | 3 |
| TNPO2 | IRS2 | 0.739179 | 3 | 0 | 3 |
| TNPO2 | ZNF791 | 0.715563 | 4 | 0 | 4 |
| TNPO2 | CTXN1 | 0.711516 | 3 | 0 | 3 |
| TNPO2 | CYTH3 | 0.710369 | 3 | 0 | 3 |
| TNPO2 | SMKR1 | 0.704506 | 3 | 0 | 3 |
| TNPO2 | ZNF805 | 0.699359 | 3 | 0 | 3 |
| TNPO2 | RPRD2 | 0.696205 | 4 | 0 | 4 |
| TNPO2 | METAP1D | 0.695226 | 3 | 0 | 3 |
| TNPO2 | LRRC49 | 0.69174 | 3 | 0 | 3 |
| TNPO2 | TMEM181 | 0.687478 | 3 | 0 | 3 |
| TNPO2 | CSRNP2 | 0.686649 | 4 | 0 | 3 |
| TNPO2 | ZNF142 | 0.684952 | 3 | 0 | 3 |
| TNPO2 | MTFR2 | 0.680792 | 4 | 0 | 4 |
| TNPO2 | ADNP2 | 0.677675 | 4 | 0 | 4 |
| TNPO2 | PPFIA1 | 0.677614 | 3 | 0 | 3 |
| TNPO2 | B3GALT6 | 0.669918 | 3 | 0 | 3 |
| TNPO2 | ZNF260 | 0.669228 | 3 | 0 | 3 |
For details and further investigation, click here
