ZNF558

 

Full name: zinc finger protein 558 Alias Symbol: FLJ30932
Type: protein-coding gene Cytoband: 19p13.2
Entrez ID: 148156 HGNC ID: HGNC:26422 Ensembl Gene: ENSG00000167785 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ZNF558:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF558 148156 227810_at 0.2713 0.4258
GSE26886 ZNF558 148156 227810_at 0.9990 0.0000
GSE45670 ZNF558 148156 227810_at 0.5073 0.0031
GSE53622 ZNF558 148156 42929 0.4965 0.0000
GSE53624 ZNF558 148156 42929 0.6358 0.0000
GSE63941 ZNF558 148156 227810_at -0.1697 0.7446
GSE77861 ZNF558 148156 227810_at 0.3037 0.1237
GSE97050 ZNF558 148156 A_23_P28015 -0.1903 0.5574
SRP007169 ZNF558 148156 RNAseq 1.2858 0.0079
SRP008496 ZNF558 148156 RNAseq 1.7732 0.0000
SRP064894 ZNF558 148156 RNAseq 0.8123 0.0017
SRP133303 ZNF558 148156 RNAseq 0.1469 0.3566
SRP159526 ZNF558 148156 RNAseq 0.3243 0.2377
SRP193095 ZNF558 148156 RNAseq 0.3018 0.0121
SRP219564 ZNF558 148156 RNAseq 1.1721 0.0551
TCGA ZNF558 148156 RNAseq 0.0425 0.4508

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by ZNF558 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF558:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF558 148156 4 3 23
GSE20123 ZNF558 148156 3 2 25
GSE43470 ZNF558 148156 2 5 36
GSE46452 ZNF558 148156 47 1 11
GSE47630 ZNF558 148156 5 7 28
GSE54993 ZNF558 148156 16 2 52
GSE54994 ZNF558 148156 6 14 33
GSE60625 ZNF558 148156 9 0 2
GSE74703 ZNF558 148156 2 4 30
GSE74704 ZNF558 148156 0 2 18
TCGA ZNF558 148156 10 19 67

Total number of gains: 104; Total number of losses: 59; Total Number of normals: 325.  


 

Somatic mutations of ZNF558:

 

Generating mutation plots.

 

Highly correlated genes for ZNF558:

 

Showing top 20/1389 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF558FAM168A0.858608303
ZNF558PRR120.827853303
ZNF558GDE10.816132303
ZNF558RAVER10.790797303
ZNF558NDUFB40.777033303
ZNF558ZFYVE90.771237303
ZNF558INPP5B0.764147303
ZNF558PEX100.759642303
ZNF558TGFB1I10.750506303
ZNF558TNPO20.748309404
ZNF558SLC38A60.740627505
ZNF558ANO60.737585303
ZNF558CEP3500.734884404
ZNF558PMF10.733793303
ZNF558FMR10.733254303
ZNF558TADA10.721908303
ZNF558GATAD2B0.721132303
ZNF558CAMKK10.717355303
ZNF558TRPM40.716447403
ZNF558MCMBP0.713651303

For details and further investigation, click here